Associate Principal Scientist, Immunology Discovery
Merck
Merck seeks an Associate Principal Scientist in Immunology Discovery to lead early-to-late stage drug discovery programs for inflammatory and autoimmune diseases. The role involves directing cross-functional teams, designing innovative research strategies, and advancing therapeutic candidates from discovery through clinical development in San Diego.
Responsibilities
- Define and execute drug discovery immunology project strategies across multiple programs
- Lead cross-functional teams to advance therapeutic candidates from early discovery to clinical stage
- Present program recommendations and strategic decisions to senior governance committees
- Design, execute, and interpret complex in vitro and ex vivo immunology studies independently
- Identify and implement innovative approaches and technologies to increase program efficiency and productivity
Requirements
- Ph.D. in immunology, cell biology, or related biomedical science with 5+ years experience
- Demonstrated leadership of early-to-late stage discovery programs in matrixed environments
- Strong immunology background with knowledge of immune-mediated diseases in gastroenterology, rheumatology, or dermatology
- Expertise in cell culture, flow cytometry, immunoassays, and molecular biology techniques
- Proficiency with data analysis tools including Excel, GraphPad Prism, and FlowJo
- Strong cross-functional collaboration and mentoring abilities
- Excellent communication of complex data and program strategies to diverse audiences
$142.4k - $224.1k
...improving the lives of patients. The Discovery Immunology organization is developing and advancing... ...needs. We are seeking anAssociate Principal Scientistwith strong background in Immunology... ...mentorship to less experienced scientists to ensure a culture of scientific rigor...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$142.4k - $224.1k
...Associate Principal Scientist position in immunology discovery at Merck focused on leading translational research activities. The role involves designing experiments with primary immune cells and patient samples, developing disease models, and generating decision-enabling...Principal$142.4k - $224.1k
...Job Description The Associate Principal Scientist will lead translational discovery activities through strong expertise in immune cell biology, human disease... ...experiments to validate therapeutic targets in immunology, inflammation, and autoimmunity. Develop disease...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- Associate Principal Scientist, Medicinal ChemistryWe are seeking an accomplished medicinal chemist and project leader to drive drug discovery programs from Hit-to-Lead through Development Candidate nomination. The individual will define and execute medicinal chemistry strategy...PrincipalSummer holidayLocal area
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...ABOUT THE ROLE We are seeking a Scientist I (Ph.D. or equivalent, with approximately... ...test therapeutic molecules emerging from discovery biologics workstreams. You will closely... ...in protein sciences, analytics, and immunology to support lead discovery, characterization...Full timeRelocation packageFlexible hours$165k - $185k
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...Summary: We are seeking a Discovery Program Leader (DPL) to... ...meetings focused primarily on immunology and oncology . This position... ...and assess potential risks associated with therapeutic targets or... ...experience as a non-clinical safety scientist (e.g. Toxicology, Pathology...PrincipalFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work- ...people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in... ..., Instagram, X and YouTube. Job Description The Principal Scientist, In Vivo Preclinical Development will play a key role in the...PrincipalContract workLocal area
- ...OPPORTUNITY We are seeking a highly motivated Senior Scientist to join our R&D Operations team and advance... ...at the cutting edge of antibody engineering, immunology and immune‑oncology contributing to groundbreaking drug discovery. KEY RESPONSIBILITIES Design and Execute...PrincipalFull timeFlexible hours
$45 - $55 per hour
...Senior / Associate Scientist, Translational Comp: $45 - $55/hr DOE Status: Contractor Must be in San Diego... ...translational researcher to drive biomarker discovery and translational studies across oncology, immunology, and in vivo pharmacology programs. You'll run...For contractors- ...The Role We are seeking an exceptionally driven, discovery-minded Senior Scientist / Principal Scientist to lead mRNA molecule design and platform innovation... ...provide day-to-day scientific direction to research associates and junior scientists, with potential oversight of...PrincipalFull time
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...SUMMARYWe are seeking a highly skilled and motivated Senior Associate Scientist to join the Chemistry team at Iambic Therapeutics headquarters... ..., and software engineers throughout all stages of discovery, from hit identification and lead optimization through candidate...Flexible hours$102k - $128k
JOB SUMMARYWe are seeking a motivated and hands-on Senior Associate Scientist I/II, Purification Sciences to support small-molecule drug discovery. This individual will perform chromatography-based purification, with a focus on preparative LC and preparative SFC, supporting...Flexible hours$102k - $128k
JOB SUMMARYWe are seeking a motivated and detail-oriented Sr. Associate Scientist to join our Discovery Chemistry team at Iambic Therapeutics in San Diego, CA. In this role, the successful candidate will apply hands-on synthetic chemistry skills to execute high-throughput...Flexible hours- ...Job Title: Principal Scientist, In Vitro Pharmacology Department: Pharmacology Reporting to: Senior Director, Pharmacology Location... ...investors, Sirius is dual headquartered in San Diego, where discovery center is located, and Shanghai, where translational...PrincipalFull time
- ...Job Title: Principal Scientist, In Vivo Pharmacology Department: Pharmacology Reporting to: Senior Director, Pharmacology Location... ...investors, Sirius is dual headquartered in San Diego, where discovery center is located, and Shanghai, where translational medicine...PrincipalFull time
- ...Formulation & Analytical Support Scientist (Contract) Location: San Diego, CA (on-site) | Type: Contract, approx. 6 months, extension... ...or toxicology studies. Background supporting small-molecule discovery or pharmaceutical development. Familiarity with formulation...Contract work
$88k - $136k
...Description: This position is for an in vitro/in vivo Associate Scientist reporting to the Senior Director of Pharmacology. We seek an... ...rigor and excellent communication skills to support our drug discovery programs. Initially, the position will have a strong focus on...Full timeRelocation packageFlexible hours- Neomorph is seeking an experienced associate scientist with a passion for drug discovery and extensive experience with BSL2/2+ practices and routine molecular and cell biology techniques. The role will be critically involved in supporting Neomorph's internal pipeline through...Summer holidayLocal area
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...a vibrant global community of talented scientists and researchers from over 30 countries.... ...learn, innovate, and make breakthrough discoveries that improve human health.Together, we... ...target identification. We are seeking an Associate Scientist to work on exciting projects...Local areaWorldwideRelocationFlexible hoursShift work$144.4k - $216.6k
...technology and full automation to accelerate Vertex’s internal drug discovery pipeline. These instruments are tailored to specific project... ...available.We are seeking an experienced and innovative Principal Scientist with expertise in optical design, microscopy, and functional...PrincipalFull timeSummer workFlexible hours$105k - $169.05k
...recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development... ...the medicines of tomorrow. About Immunology Our expertise in Innovative Medicine... ...for the best talent for a Senior Scientist to join the Discovery Immunology group...Full timeLocal areaImmediate start$155k - $175k
...We are a stealth mode early stage immunology company, specifically inflammation and auto... ...interviews. Role Description The Senior Scientist will lead the design, execution, and... ...of 8+ years of experience in drug discovery in pharma or biotech required. • Bachelors...Full timeLocal area
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