Principal, Biostatistician

Principal, BiostatisticianThe Principal, Biostatistician will own the statistical and quantitative work that connects clinical evidence to the most important decisions Roivant makes across its pipeline. This is not a strategy role — this is a figure-things-out and get-things-done role in a high-stakes environment with substantial ownership. We expect you to get to ground truth on the hardest clinical and scientific questions the company faces, working directly in trial datasets and translating rigorous analysis into recommendations that leadership acts on.The Principal will pressure-test the clinical assumptions underpinning key pipeline and commercial decisions, build the statistical frameworks needed to evaluate evidence across assets, and ensure Roivant has a clear-eyed view of what its data shows. The scope is intentionally broad and is well-suited to a high-potential individual earlier in their career with exceptional upside and a strong desire to take on responsibility.ResponsibilitiesWork directly in ongoing and completed clinical trial datasets (CSRs, patient-level data, interim readouts) to identify efficacy signals, safety patterns, and subgroup effects that inform go/no-go and commercialization decisionsBuild rigorous statistical analyses from scratch: mixed-effects models, longitudinal models, Bayesian frameworks, subgroup analyses, and sensitivity analyses across Roivant's pipeline assetsMonitor emerging safety signals and unexpected findings in real time across ongoing studies; surface and contextualize them for leadership before they become surprisesPressure-test clinical assumptions: challenge endpoint choices, scrutinize statistical analysis plans, and flag where the data does not support the narrativeExecute focused 1-5 day analytical sprints on the highest-priority questions from Roivant and Vant leadershipEvidence Synthesis & Competitive IntelligenceDevelop a deep, differentiated read of the clinical evidence base for Roivant's near-commercial assets: what the data shows, what it does not, and where the science is genuinely uncertainAnalyze competitors' trial data, published and unpublished, with the same rigor applied to Roivant's own: endpoints, patient populations, effect sizes, and durabilitySynthesize findings from literature, registries, claims, and proprietary datasets into coherent evidence narratives that hold up under scrutinyData Infrastructure & Cross-Platform WorkDrive selection and integration of the data sources needed to support portfolio decisions, including claims, labs, clinical trial data, and genomicsHelp build shared analytical infrastructure across Roivant and Vant companiesIdentify opportunities to apply consistent statistical frameworks across assets and therapeutic areasQualificationsAdvanced degree in biostatistics, statistics, epidemiology, or a closely related quantitative field; direct experience in clinical trial statistics strongly preferredHands-on fluency with clinical trial data; you have worked directly in patient-level datasets, not just read summaries of analyses others ranDeep command of statistical methods used in clinical development: mixed-effects models, longitudinal and repeated-measures analyses, Bayesian approaches, multiplicity adjustment, and sensitivity analysesFamiliarity with clinical trial design and regulatory statistical frameworks (ICH E9, estimands, SAP development)Track record of translating rigorous analysis into decisions; your numbers have changed somethingAble to present complex statistical findings clearly to non-technical audiences, including CEO-level stakeholdersIntensely curious, resourceful, and motivated; you run toward hard, ambiguous problemsCompensation & BenefitsThis is a full-time position. The role offers meaningful equity participation and a comprehensive company-sponsored benefits package.Base salary will be determined during the interview process and will vary based on multiple factors, including prior experience, relevant expertise, current business needs, and market conditions. The expected base salary will generally be between $130,000 to $220,000 per year at commencement of employment, but the final salary offered may be outside this range based on individual circumstances.This position is at-will and Roivant reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance and business and market conditions.Roivant Sciences provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.