Logistics & Distribution Senior Manager

Job Description General Summary: The Senior Manager of Cold Chain Logistics Process is responsible for leading the development and implementation of processes and procedures to ensure the success of cold chain logistics operations within Vertex Pharmaceuticals. This position requires close collaboration with logistics service providers, order management teams, quality assurance, packaging engineering, and other stakeholders to ensure adherence to regulatory guidelines and meet business needs. The Senior Manager will be an integral member of the logistics team, working to develop a robust logistics network to support pipeline programs, evaluate and launch logistics and supply chain information systems, and manage all quality systems from open to closure. Key Duties and Responsibilities: Develop and implement standard operating procedures and work instructions with global contract manufacturing organizations and logistics service providers to ensure product quality and business needs are met. Manage quality systems, including deviations, CAPAs, and change controls, from open to closure. Work with logistics leadership to develop a robust logistics network to support pipeline programs, including supplier qualification, shipping validation, and lane selection. Evaluate, build, and launch logistics and supply chain information systems in conjunction with the Supply Chain Process and Systems lead and GIS. Ensure shipments plans are on time and compliant by working with key stakeholders such as Technical Operations, Trade Compliance, QA, and Supply Chain Planning. Define, measure, and communicate key performance indicators and supportive metrics that track the effectiveness of logistics and distribution operations. Participate in quality exceptions and solve complex logistical issues, selecting modes of transport as necessary. Ensure compliance with regulations such as Good Distribution Practices. Lead process redesign workshops and manage process changes. Educate business users responsible for managing and operating business processes. Monitor, measure, and provide feedback on process performance. Facilitate process workshops that involve eliciting process requirements and liaising with users. Coordinate the development of SOWs and POs. Assume business process ownership of new capabilities as required. Review and/or implement changes to controlled documents as needed. Perform other duties as assigned. Knowledge and Skills: Direct experience managing logistics of Cell and Gene Therapy programs and short lead time cold chain operations. Familiarity managing logistics with a network of both internal and external (CDMO) manufacturing sites. Demonstrated ability to work effectively in a collaborative and fast-paced team environment, including business leadership to build alignment. Excellent understanding of Good Distribution Practices in the Pharmaceutical Industry. Working knowledge of Trade Compliance requirements. Fluency and proficiency with standard logistics and distribution activities In-depth analytical skills, strong verbal and written communications skills Demonstrated ability to work effectively in a collaborative and fast-paced team environment, including influencing business leadership to build alignment around a topic/issue Highly skilled in data analysis, manipulation, and presentation, to include software skills with Microsoft Excel, Word, PowerPoint, Visio, and Access Strong understanding of ERP systems; knowledge of Oracle-based systems a plus Education and Experience: Bachelor's degree in engineering or scientific, business or related discipline MS in Engineering, Business Management, Information Technology, Financial Management, or a similar relevant field. Typically requires 6 years of experience or the equivalent combination of education and experience in logistics and distribution Pay Range: $128,600 - $192,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion – you’re always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Remote Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.