Senior Director, Protein Therapeutics PK/PD & Bioanalysis
MSD Malaysia
MSD Malaysia is seeking a Senior Director based at research labs in Boston, MA to lead efforts on protein therapeutics from discovery to first-in-human trials. This position involves overseeing the design and interpretation of pharmacokinetic and immunogenicity studies, mentoring team members, and contributing to global PDMB strategies through collaboration across sites. The ideal candidate will possess a Ph.D. and 7+ years of experience in relevant fields, with a proven track record in leading protein therapeutic discovery efforts. #J-18808-Ljbffr MSD Malaysia
$194.1k - $305.6k
...PDMB) group is seeking a Senior Director to contribute to our company’s protein therapeutic efforts from discovery... ...optimization (PK, distribution, translational... ...pharmacological response (PK/PD), and safety.... ...ADME, Assay Development, Bioanalysis, Bioanalytical Assays,...Senior$194.1k - $305.6k
...strategic thinking and collaborative Senior Director to contribute to our Company's protein therapeutic efforts from discovery through... ...and operational oversight for PK/PD and bioanalytical activities... ...: ADME, Assay Development, Bioanalysis, Bioanalytical Assays,...SeniorFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$177k - $308k
...Development: Build and validate predictive models across key ADMET and PK/PD endpoints — including clearance, permeability, solubility,... ...models for tissue distribution, volume of distribution, plasma protein binding, and blood‑brain barrier penetration. Ensure models are...SeniorFull timeFlexible hours- Regeneron Pharmaceuticals, Inc is seeking a Senior Director to lead Quantitative Pharmacology activities. This role is pivotal in ensuring the success of drug safety initiatives throughout early clinical development and beyond. The ideal candidate will possess a PhD or...Senior
$119.7k - $222.3k
...an enthusiastic and motivated PK Sciences representative to... ...includes small molecules, biologics/therapeutic proteins, antibody drug‑conjugates,... ...nonclinical and clinical PK/PD relationships and development... ...to be considered for Senior Principal Scientist. Extensive...Senior$108.5k - $201.5k
...are seeking an enthusiastic and motivated PK Sciences project team representative to... ...includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies... ...to elucidate the understanding of PK/PD relationships and develop dosing...Full time$212k - $333.19k
...drives portfolio decisions, integrating ADME, PK, PBPK/QSP, and AI‑enabled modeling to... ...Decision Leadership : Owns the DMPK, PK/PD, and modeling strategy across the AIRx portfolio... ...datasets. Experience in at least one therapeutic area represented across the Takeda...SeniorFull timeTemporary workLocal areaRemote work$212k - $333.19k
...drives portfolio decisions, integrating ADME, PK, PBPK/QSP, and AI‑enabled modeling to... ...& Decision Leadership: Owns the DMPK, PK/PD, and modeling strategy across the AIRx portfolio... ...datasets. Experience in at least one therapeutic area represented across the Takeda...SeniorMinimum wageFull timeTemporary workLocal areaRemote work$213k - $280.5k
Vesalius is seeking a Senior/Executive Director-level Head of Biology to lead biological strategy and target validation across our causality‑driven... ...and for shaping preclinical programs across multiple therapeutic areas. The ideal candidate brings deep target validation...Senior$222k - $272k
## Senior Director, Head of DMPK/ADMEApplylocations: Boston, MA, UStime... ...peptides, mAbs, VHHs, and mini‐proteins - and by leading teams... ...Deliver high‐quality nonclinical PK summaries and integrated... ...DMPK, Immunogenicity, Clinical Bioanalysis, Modeling & Simulation, and...SeniorImmediate start$212k - $333.19k
...programs down in large pharma. AI-enabled protein design, internal or externalized wet lab... ...absorption, immunogenicity risk assessment, and PK/PD modeling for dose projection Strong... ...convey complex large molecule science to senior governance audiences and distill...SeniorMinimum wageFull timeTemporary workLocal areaRemote work$177k - $308k
...science in this field, we are seeking a scientific director who is experienced in mechanistic PK, PK/PD, and/or PBPK modeling of novel modalities. We are passionate... ...talent across technical and people‑leader tracks. Therapeutic area expertise within neuroscience. Experience with...SeniorFull timeWorldwide$98.7k - $183.3k
...Summary LI#-Onsite (Lab Based) Internal Title: Senior Scientist II Location: Cambridge This... ...and high performing global discovery bioanalysis team and play a key role as a senior lab... ...bioanalytical support investigating the PK/TK properties of low molecular weight and...SeniorLocal areaRelocation packageShift work$183k - $231k
...antibodies. We are seeking an accomplished protein scientist and people leader to build and... ...into well-characterized, developable therapeutic proteins. This is a rare opportunity to... ...moves from sequence to drug candidate. The Director/Sr. Director of Protein & Cell Sciences...$242k - $403.3k
Build Our Future Together In this capacity the Senior Director is accountable for the successful and timely completion of Quantitative Pharmacology... ...to enable their success. Utilizing a mastery level of PK/PD knowledge and strategic leadership skills, effectively...Senior$160.3k - $297.7k
...directly. Summary Job Title: Associate Director and Senior Principal, AI Methods, AI for Research... ...pipeline. From identifying novel therapeutic targets to accelerating clinical translation... ...learning to target identification, protein modelling, or translational research...SeniorFull timeRelocation package$212k - $333.19k
Senior Director, Computational Chemistry Takeda Research is constructing the Discovery Automation... ...with advances in generative AI, protein structure prediction, and ML methods;... ...Regular Time Type: Full time Job Exempt: Yes #J-18808-Ljbffr Initial Therapeutics, Inc.SeniorMinimum wageFull timeTemporary workLocal areaRemote work$212k - $333.19k
Job Description Senior Director, AIRx Medicinal Chemistry Takeda Research is constructing the Discovery Automation... ...based drug design; ability to read and apply protein‑ligand structural data. Experience in one or more therapeutic areas across the Takeda Research portfolio...SeniorMinimum wageFull timeTemporary workLocal areaRemote work$229.5k - $310.5k
...s biocatalysis strategy, build internal protein screening and engineering capabilities,... ...risk assessments, and recommendations to senior stakeholders.Qualifications:PhD in Biochemistry... ...: AlnylamWe are the leader in RNAi therapeutics - a revolutionary approach with the...SeniorFull timeTemporary workLocal areaFlexible hours$202.4k - $323.4k
Director/Senior Director, Molecular Discovery Cambridge, MA USA The Director, Molecular Discovery... ...(potency, selectivity, ADMET, PK, safety) well enough to guide them or define... ...infrastructure. Background across multiple therapeutic areas, giving you breadth in target...SeniorFull timeWork at officeLocal areaFlexible hours$222k - $272k
...capabilities across multiple modalities—peptides, mAbs, VHHs, and mini‑proteins—and by leading teams through complex scientific and... ...risk‑based decision framework. Deliver high‑quality nonclinical PK summaries and integrated DMPK data packages to support project decision...Senior- ..., and healthcare innovators have deep sector expertise across therapeutics, diagnostics, devices and services. They have brought hundreds... ...About the Role We are seeking a highly skilled computational protein scientist to execute complex protein design and modeling work...Senior
$196.7k - $353.4k
Senior Director, Head of Quantitative Systems Pharmacology (QSP) Responsibilities Develop and implement QSP strategy across priority therapeutic areas and modalities. Embed QSP principles into Moderna’s... ...stages. Deep understanding of PK/PD, systems biology, disease pathway...Senior$196.7k - $353.4k
...collaborative, and strategic leader to serve as Senior Director, Head of Quantitative Systems... ...implement QSP strategy across priority therapeutic areas and modalities. Embed QSP principles... ...clinical). Deep understanding of PK/PD, systems biology, disease pathway modeling...SeniorPermanent employment$302k - $350k
...dermatology. Could you be our next Senior Director, Immunology and Translation? The job is... ...week. You will report to the Research Therapeutic Area Lead, Immunology/Transplant and Vaccines... ...of plasma fractionation, recombinant protein technology, and cell and gene therapy...SeniorWork at office3 days per week- Regeneron Pharmaceuticals, Inc in Cambridge, MA is seeking a Director in Pharmacometrics to manage quantitative analyses for research and development programs. This role requires expert knowledge in pharmacokinetics and pharmacodynamics, as well as excellent communication...
$252k - $378k
## Senior Director, US Medical Affairs – NephrologyApplylocations: Boston, MAtime type: Full timeposted on: Posted Todayjob requisition... ...scientific knowledge of nephrology, immunology, or related therapeutic areas, including familiarity with the US treatment landscape...SeniorSummer workRemote workFlexible hoursShift work2 days per week$210k - $280k
...innovators have deep sector expertise across therapeutics, diagnostics, devices and services.... ...delivery platform. The Position The Senior Director/Director Biology will report directly... ...discipline such as chemistry or protein engineering. It is understood that education...SeniorFull timeShift work$210.9k - $379.2k
...patients' lives worldwide. Moderna is seeking a Global Medical Director to lead medical affairs strategy across our Oncology portfolio... ...or immuno‑oncology settings. Deep expertise in oncology therapeutic area required Strong strategic thinking and leadership skills...SeniorPermanent employmentWork at officeWork from homeWorldwide$286.9k
...Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology Translational Medicine in our Research & Development Division is... ...clinical strategy for novel Immunology assets and therapeutics, including authoring initial clinical and biomarker...SeniorFor contractorsWork at officeRemote workWorldwideMonday to FridayMonday to ThursdayShift work3 days per week
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