Principal Scientist

Company Description HexemBio is a biotechnology company developing regenerative therapies based on the Synthetic Human Yolk Sac, a platform designed to rejuvenate aging blood stem cells by recreating their original developmental environment. By restoring the regenerative capacity of a patient’s own hematopoietic stem cells, the company aims to enable new approaches to extending human healthspan. To learn more, visit hexemb.io. Role Description We are hiring a senior scientist to perform process development for our stem cell programs as an early member of the team.This is a hands on role with real ownership. You will design and run the work at the bench, define the process, and work directly with the founders. What you will do Develop, optimize, and document scalable culture processes for pluripotent stem cell derived material and primary hematopoietic cells Perform in process controls, critical process parameters, and release assays, and drive them from bench scale toward clinical scale Execute and troubleshoot at the bench, including differentiation, expansion, harvest, and formulation steps Design characterization and potency assays and interpret data that shapes program and regulatory decisions Support technology transfer to CDMO partners and contribute to CMC sections of regulatory filings Train and mentor junior scientists at the bench Work with leadership to set research priorities and scientific direction What we are looking for PhD or MD PhD in stem cell biology, cell biology, bioengineering, or a related field 3 or more years of industry experience in cell therapy or regenerative medicine process development Demonstrated track record in pluripotent stem cell work through publications, patents, or comparable accomplishments Hands on expertise across cell culture at scale, flow cytometry, colony forming unit assays, qPCR, and standard molecular biology Working familiarity with cGMP concepts, in process controls, assay qualification, and documentation practices Genuine bench expertise, and the intent to keep doing it Willingness to work around the timepoint demands of primary and pluripotent cell culture, including occasional weekend or off hours work Track record of moving fast without losing rigor in an early stage environment where priorities shift Foundational role at a stage early enough that your work defines the platform and the process Direct collaboration with the founders and an advisory network that includes leaders in synthetic biology, drug delivery, and FDA regulatory strategy Competitive salary, meaningful equity, and benefits. #J-18808-Ljbffr