Regional Director, GU Oncology Sales

Location: East US Region

Natera is seeking an experienced Regional Director to build, lead, and develop a team of Clinical Oncology Specialists focused on Genitourinary (GU) cancers across the Eastern United States.

This specialized sales team will drive adoption of Natera’s Signatera™ molecular residual disease (MRD) test , with a primary focus on Urologic Oncology. Key call points include Urologic Oncologists, GU Surgical Oncologists, Radiation Oncologists, Medical Oncologists, Pathologists, and other healthcare providers involved in the diagnosis, treatment, and ongoing management of patients with genitourinary cancers.

Signatera is a personalized, tumor-informed circulating tumor DNA (ctDNA) assay designed to detect molecular residual disease and monitor disease recurrence. Across GU cancers, including bladder, renal cell carcinoma, and testicular cancers, Signatera provides highly specific molecular insights that can help clinicians better assess recurrence risk, monitor disease status, and inform individualized patient management strategies.

The Regional Director will drive sales performance, ensure sales goals and management objectives are achieved or exceeded, and collaborate with cross-functional teams to develop and execute business strategies aligned with Natera Oncology's broader corporate objectives.

Key Responsibilities

• Hire, coach, develop, and lead a team of approximately 10 Clinical Oncology Specialists focused on GU cancers, driving Signatera adoption and achieving regional sales objectives.
• Establish a strong field leadership presence through strategic business planning, coaching, CRM utilization, Core Oncology Sales collaboration, and regular field engagement.
• Develop and execute regional sales strategies targeting Urologic Oncologists, GU Surgical Oncologists, Medical Oncologists, Pathologists, and other key stakeholders across academic and community oncology settings.
• Build and strengthen relationships with Key Opinion Leaders (KOLs) specializing in GU cancers, particularly within major academic medical centers, leading urology practices, and community oncology networks.
• Drive awareness, education, and adoption of Signatera within GU Oncology, with an emphasis on bladder, kidney, and testicular cancers.
• Develop expertise in Natera's molecular diagnostics technology, clinical evidence, and service offerings, effectively representing the company with KOL physicians, academic and community medical directors, and executive-level stakeholders.
• Oversee recruitment, hiring, onboarding, training, and performance development of GU Clinical Oncology Specialists.
• Conduct regular field visits with sales professionals to provide coaching, reinforce clinical and commercial knowledge, and support individual and team performance.
• Collaborate closely with Natera's Core Oncology Sales team and cross-functional partners to align account strategies, expand market opportunities, and maximize commercial effectiveness.
• Monitor market trends, competitive dynamics, and evolving clinical evidence in GU Oncology to identify opportunities for growth and regional expansion.
• Develop and execute regional business plans aligned with sales objectives, market opportunities, and available resources.
• Optimize regional and territory alignment to maximize market coverage, sales productivity, and return on investment.
• Establish best practices for territory management, strategic account planning, physician engagement, and sales execution.
• Attend relevant local, regional, and national oncology and urology conferences, industry meetings, and training sessions.
• Support career development and succession planning by providing ongoing mentorship and leadership development opportunities.
• Ensure all employees complete required training related to HIPAA/PHI privacy, company policies, compliance, and security within 30 days of hire.
• Support Signatera and Natera's broader Oncology portfolio as needed.

Qualifications

• Bachelor's degree in Business, Marketing, Life Sciences, or a related field required; MBA preferred.
• Minimum of 10 years of successful sales experience within Oncology, Molecular Diagnostics, Clinical Diagnostics, Urology, Medical Devices, or the diagnostic laboratory industry.
• Minimum of 5 years of sales leadership experience, preferably within Oncology, Specialty Diagnostics, or a related healthcare market.
• Experience in Genitourinary (GU) Oncology, Urologic Oncology, Urology, or GU Surgical Oncology strongly preferred.
• Experience selling into academic medical centers, large healthcare systems, and/or community oncology practices preferred.
• Experience launching new products, developing specialized markets, or leading teams through periods of significant growth preferred.
• An equivalent combination of academic and professional experience will be considered.
• Ability to travel up to 75%.

Knowledge, Skills, and Abilities

• Strong leadership and coaching skills with the ability to recruit, develop, motivate, and retain high-performing sales teams.
• Strategic mindset with the ability to translate business objectives into actionable regional sales plans.
• Understanding of the GU Oncology landscape, including key physician specialties, treatment pathways, and market dynamics.
• Knowledge of molecular diagnostics, ctDNA, MRD testing, and precision oncology preferred.
• Ability to establish and maintain strong relationships with Key Opinion Leaders (KOLs), physician stakeholders, and healthcare executives.
• Strong business acumen with the ability to analyze market opportunities, competitive trends, and sales performance to drive growth.
• Excellent communication, presentation, negotiation, and interpersonal skills.
• Collaborative approach to working with cross-functional teams, including Core Oncology Sales, Marketing, and Medical Affairs.
• Strong problem-solving skills, sound judgment, and the ability to navigate complex business environments.
• Results-oriented leadership style with a strong sense of accountability, urgency, and adaptability.
• Strong organizational and time management skills.
• Proficiency in Microsoft PowerPoint, Excel, Gmail, and Salesforce.com.

Why Join Natera?

Join Natera and play a pivotal role in advancing precision oncology for patients with genitourinary cancers.

This is an exciting opportunity to lead a specialized sales team at the forefront of molecular diagnostics, driving adoption of innovative MRD technology across the GU Oncology landscape.

As Regional Director, you will have the opportunity to build and develop a high-performing team, establish strategic partnerships with leading Urologic Oncologists and cancer centers, and help expand access to Signatera's personalized approach to cancer monitoring.

Compensation & Benefits

The total on-target earnings package includes a competitive base salary and uncapped quarterly commissions. Additional compensation includes a car allowance and Restricted Stock Units (RSUs).

The compensation package listed is for 1st year OTE, which are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. On-target earnings (OTE) represent the total potential income an employee can earn by achieving 100% of their performance goals. It combines a base salary with commissions and serves as an estimated figure rather than a guaranteed amount, providing a guideline based on average performance outcomes.

On-target earnings (OTE)

$240,000—$280,000 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

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Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page