Medical Director, Breast Cancer Diagnostics - US Medical Affairs

At AstraZeneca, we are united by a bold ambition: to eliminate cancer as a cause of death. Our Oncology team is advancing one of the industry's broadest and deepest pipelines, delivering scientific innovations that are transforming outcomes for patients worldwide. As we continue to pioneer precision medicine, we are seeking a visionary Medical Director, Breast Diagnostics to shape the future of diagnostic strategies across our breast cancer portfolio.

This is a unique opportunity to work at the intersection of oncology, diagnostics, medical affairs, and scientific innovation. You will play a critical role in ensuring patients are accurately identified for the right therapies at the right time while helping advance some of the most exciting, targeted therapies in development and commercialization.

Why AstraZeneca?

Make a Meaningful Impact. Your work will directly influence strategies that enable precision medicine and improve outcomes for patients living with breast cancer. Partner with cross-functional partners in global medical, commercial, clinical development, and regulatory to drive innovation across breast cancer portfolio and future oncology therapies. Join a team where scientific excellence, curiosity, inclusion, and innovation are valued. Work alongside some of the brightest minds in oncology while influencing strategy across the healthcare ecosystem.

About the Role

As Medical Director, Breast Diagnostics, you will lead the development and execution of US diagnostic strategies that support precision patient identification, companion diagnostics, and testing solutions across the breast cancer portfolio. Working within US Medical Affairs, you will collaborate extensively with internal and external stakeholders to ensure diagnostic excellence throughout the patient journey.

You will serve as a scientific leader, driving innovative approaches to testing access, infrastructure, and stakeholder engagement in a rapidly evolving oncology landscape.

Key Responsibilities

• Develop and execute US diagnostic strategies across AstraZeneca's breast oncology portfolio, including current and future small molecule therapies.
• Ensure companion diagnostic and testing readiness to support successful product launches.
• Support diagnostic registration and approval activities where required.
• Build strategic partnerships with pathology organizations, diagnostic companies, laboratory networks, healthcare providers, advocacy groups, and key opinion leaders.
• Utilize medical evidence, real-world evidence, and epidemiology to support education and diagnostic adoption strategies.

Required Qualifications

• Advanced medical or scientific degree (MD, PhD, PharmD, MBBS).
• 3+ years of experience in health care delivery; including US experience and preferably oncology diagnostic or clinical lab experience, pharmaceutical experience is a plus
• Experience with oncology drug launch and/ or diagnostic product (tests) launch planning and evidence generating efforts to support diagnostic test adoption

Preferred Qualifications

• Proven experience with a broad base of external experts including pathologists, oncologists, laboratory professionals and US healthcare providers. A track record of effective management of decision-making bodies and governance
• An understanding of diagnostic FDA environment, clinical laboratory practices including CLIA lab requirements and test implementation
• Proven track record of strategic thinking, judgment and influencing skills, Strong leadership attributes to set direction, generate commitment, balance short and long-term needs, constructively resolve issues
• Proven demonstration of effective cross-functional project team leadership
• Ability to lead and influence through change
• Strong teamwork and collaboration skills

Compensation and Benefits

AstraZeneca is committed to providing competitive, equitable and transparent compensation.

The annual base pay for this position ranges from $186,831 - $280,246 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).

Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.

Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Inclusion & Diversity

AstraZeneca is an equal opportunity employer. We are committed to creating an inclusive environment where everyone can contribute, grow and succeed.

We welcome applications from individuals of all backgrounds and experiences and are committed to providing reasonable accommodation throughout the recruitment process. If you require support or adjustments, please let us know.

Ready to make an impact?

If you're energized by scientific innovation, passionate about improving patient outcomes, and excited by the opportunity to shape the future of breast cancer diagnostics, we'd love to hear from you.

Date Posted

27-Aug-2026

Closing Date

09-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.