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Research Scientist I

Medical College of Wisconsin

Summary The Data Science Institute, in collaboration with the Department of Physiology, at the Medical College of Wisconsin seeks a highly motivated Research Scientist to join a collaborative research team focused on ontology and data curation for diverse research communities. This role supports the Hogan Laboratory in the Data Science Institute and the Rat Genome Database in the Department of Physiology by developing, maintaining, enhancing, and implementing biomedical ontologies in various software, annotation, and data management applications. The incumbent will gain experience in the theory and practice of biomedical, health, and behavioral ontologies, including advanced ontology development workflows. The incumbent will also extract relevant information from published journal articles, research laboratories, and databases and integrate this information with existing data. A key project is the Advancing Prevention Research in Cancer through Ontology Tools (APRICOT) Project funded by the US National Institutes of Health (NIH), working with behavioral scientists and ontologists across three other European sites. This project is developing ontologies and associated tools and resources to be used in reporting behavior research. This position will work on the development of the Ontology for Modeling and Representation of Social Entities (OMRSE) and its interoperability with the Behaviour Change Intervention Ontology (BCIO). The position also is an integral team member of the Rat Genome Database (RGD). RGD is the dedicated NIH-funded knowledgebase for the laboratory rat, along with human and several mammalian disease models; RGD curates multiple genomic data types, comprehensive disease and phenotype annotations, and develops novel tools to effectively mine, analyze and visualize the available data. The incumbent will independently conduct data curation including data acquisition, ontology development, and analysis for research projects whose focus is to provide comprehensive disease, clinical and physiological data to diverse research communities. They will work with technical team members on the development of data analytic tools and pipelines, as well as provide input into database and user interface design. Primary Responsibilities Data curation Perform data acquisition and analysis, including identifying relevant sources of information, extracting clinical, disease, physiological and genetic information from text sources such as published literature and clinical records as well as web-based and other sources. Develop content for web-based research resources. Work with programmers and other curators to develop new and update existing data analysis tools, database design, and web interfaces. Ontology development and implementation Contribute to the development of the Ontology for Modeling and Representation of Social Entities (OMRSE); manage the issue tracker; create periodic releases; lead development meetings. APRICOT project deliverables, including but not limited to developing interoperability between OMRSE and the BCIO and the annotation of Social Determinants of Health instruments and data. Participate in APRICOT meetings, events. Contribute to the development of the Rehabilitation Ontology (REHABO); manage the issue tracker; create periodic releases; lead development meetings. Contribute to ontology and vocabulary development for the Rat Genome Database, including but not limited to the Rat Disease Ontology (RDO) Contribute to the development of the Drug Ontology (DrOn); manage the issue tracker; create periodic releases; lead development meetings. General Responsibilities Mentor graduate students and contribute to training and scientific development within the lab Assist with the development of grant proposals and collaborative research initiatives Coordinate research study activities; lead and manage projects including presenting project updates at meetings Assist in creating workshops, presentations, and educational materials May oversee the work of laboratory personnel, including training and development as well as daily work direction/delegation/prioritizing Other duties as assigned Knowledge - Skills - Abilities Required knowledge: ontology, terminology, controlled vocabularies, data models Technical knowledge: Familiarity with Web Ontology Language, Protege, GitHub, relational database management systems / SQL, public sequence databases, and model organism databases is highly desired Enthusiastic, highly motivated, and proven ability to work independently, manage time effectively, and troubleshoot experiments Strong interest and aptitude for multi-disciplinary collaboration Skills and abilities: writing skills, presentation skills, organization, time management, multi-tasking. Qualifications Minimum Required Education: PhD in Biomedical Informatics, Ontology, Molecular Biology, Physiology, Computer Science, Artificial Intelligence, Biomedical Engineering, Bioinformatics, Biological or Health Sciences or comparable field Preferred Experience: 5 years of research experience Experience reviewing and interpreting scientific literature and research data. Experience using tools for ontology development, annotation, term matching, referent tracking, semantic web. Expertise using public genomic or disease data resources and software tools, data acquisition, integration or standardization; clinical, laboratory or informatics experience. Work experience with collaborating with domain experts to solicit priorities for ontology development and formulating term definitions and axioms. Strong publication record in peer-reviewed journals. Appropriate experience may be substituted for education on an equivalent basis. Master's degree plus an additional minimum of 3 years of relevant research experience may be considered in lieu of a PhD. Physical Requirements Work requires occasionally lifting moderate weight materials, standing, or walking continuously. Work Environment Occasional exposure to dust, noise, temperature changes, or contact with water or other liquids. Work is performed in an environmentally controlled environment. Sensory Acuity Ability to detect and translate speech or other communication required. May occasionally require the ability to distinguish colors and perceive relative distances between objects. Benefits Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental. Along with Flexible Spending options 403B Retirement Package Competitive Vacation and Paid Holidays offered Tuition Reimbursement Paid Parental Leave Employee & Family Assistance Program (EFAP) Pet Insurance On campus Fitness Facility, offering onsite classes Additional discounted rates on items such as: Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc. MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering an inclusive community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic. #J-18808-Ljbffr

Vacancy posted 4 days ago
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