Director, Real-World Evidence & Health Outcomes, mRNA Vaccines

Position Summary The CPO organization partners closely with R&D and Commercial to translate cutting-edge science into measurable health outcomes, grounded in the patient voice and external insights from healthcare systems and decision-makers worldwide. Joining CPO means working across the full product lifecycle and collaborating with diverse expert teams – from Patients & External Environment and Medical Planning to Data Generation, Scientific Communications, Medical Impact, Proactive Risk Ownership and Integrated Evidence Strategy – to ensure robust evidence, clear medical insight and responsible risk ownership shape strategy and execution at scale. It’s a highly visible, purpose-driven environment where your expertise can directly influence how innovative therapies are developed, communicated and used to improve lives around the world. The Director, Real-World Evidence & Health Outcomes (RWE-HO), mRNA Vaccines will provide scientific and strategic leadership for the development and delivery of real-world evidence supporting GSK's mRNA vaccine portfolio, with a primary focus on influenza. The role will shape evidence generation across late-stage development, launch and post-marketing phases, with particular responsibility for post-marketing vaccine effectiveness studies in the United States. Working in a global, cross-functional environment, the Director will translate recommendation and access evidence needs into scientifically rigorous and operationally feasible research. The role requires deep expertise in US vaccine effectiveness research, influenza epidemiology, real-world data and causal methods, together with the ability to influence asset strategy and lead complex external collaborations. Responsibilities This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Lead and contribute to the integrated RWE-HO strategy for mRNA influenza vaccines, aligned with clinical development, medical, regulatory and commercialization priorities.
• Translate strategic evidence gaps into clear research questions and fit-for-purpose study designs across pre-launch, launch and post-marketing phases.
• Provide expert scientific input to governance decisions, investment choices, evidence prioritization and risk mitigation.
• Lead the design, implementation and interpretation of post-marketing influenza vaccine effectiveness studies in the United States and other geographies.
• Ensure studies meet appropriate standards of scientific rigor, transparency, reproducibility and fitness for their intended decision-making purpose.
• Build productive collaborations with US academic investigators, healthcare systems, data partners and vaccine effectiveness research networks.
• Partner effectively with Clinical Development, Epidemiology, Medical Affairs, Regulatory, Safety, Biostatistics, Market Access, Data Science and Commercial teams.
• Lead multiple complex projects, budgets and external research collaborations, ensuring quality, timely delivery and appropriate escalation of risks.
• Influence senior stakeholders without direct authority and communicate complex epidemiological concepts in a clear, decision-focused manner.
• Mentor colleagues and contribute to strengthening RWE-HO capabilities, standards and innovation across the organization.

Why You? Basic Qualifications: We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• PhD, ScD, DrPH, MD, PharmD, MPH or equivalent advanced degree in epidemiology, public health, pharmacoepidemiology, health outcomes research or a related quantitative discipline.
• 5+ years experience in real-world evidence, epidemiology or health outcomes research within the pharmaceutical or vaccine industry, academia, public health or a comparable environment.
• Experience designing, conducting and interpreting post-marketing vaccine studies in the United States.
• Research experience with vaccine effectiveness studies.
• Experience using large US healthcare databases, including administrative claims, electronic health records or linked real-world datasets.
• Experience leading complex studies from concept through delivery, interpretation and scientific dissemination.
• Demonstrated effectiveness in global, cross-functional matrix teams and in managing internal and external stakeholders.

Preferred Qualifications: If you have the following characteristics, it would be a plus:

• Direct experience with influenza vaccine effectiveness studies in the United States.
• Experience with US Medicare, commercial claims, EHR and linked claims/EHR data.
• Knowledge of US influenza vaccination recommendations, vaccine delivery and healthcare systems.
• Experience studying severe influenza, hospitalization, cardiovascular complications or other downstream outcomes.
• Experience leading global evidence-generation plans or multi-country observational studies.

What success looks like The successful candidate will combine deep technical expertise with strategic asset-level thinking. They will design credible US post-marketing studies, anticipate the methodological challenges specific to influenza, and convert complex evidence needs into practical solutions. They will be a trusted scientific partner who can influence decisions, build external credibility and deliver evidence that supports the value and appropriate use of GSK's mRNA vaccines. Are you ready to help shape the future of vaccination with meaningful evidence that impacts patient care? If this role speaks to your passion and experience, we encourage you to apply and grow with us at GSK. Your contribution matters. #LI-GSK Skills Cross-Functional Leadership, Digital Fluency, Enterprise Thinking, Evidence Based Decision Making, Flexible Mindset, High Impact Communication, Launch Excellence, Patient Journey

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $203,775 to $339,625. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit [GSK US Benefits Summary]( to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - [View email address on joinrs.com](mailto:View email address on joinrs.com) GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at [