Laboratory Technician II-Department of Neurosurgery-RNA Lab

Classification Title:

Laboratory Technician II

Classification Minimum Requirements:Associate's degree in an appropriate area and two years of related experience; or a high school diploma or equivalent and four years of related experience. Appropriate college course work or vocational/technical training may substitute at an equivalent rate for the required experience.

Job Description:

Clinical Trial Sample Processing and Sample Management
Under general supervision:

• Perform human clinical trial biospecimen processing, including peripheral blood mononuclear cell (PBMC) isolation, processing, and cryopreservation, serum processing, CTC processing and tissue banking for all clinical biopsies from patients.
• Process, label, store, and bank clinical research samples according to study protocols and laboratory procedures.
• Maintain accurate electronic and paper records related to sample collection, processing, storage, and shipment.
• Assits with Organizing and tracking clinical specimens to ensure proper chain of custody and sample integrity.
• Assist with maintaining clinical trial documentation and study records.
• Monitor inventory levels and help order supplies required for clinical sample processing activities.
• Follow established SOPs and assist with SOP updates as directed

Clinical Immune Monitoring and Research Support

• Assist with clinical immune-monitoring studies using patient-derived samples.
• Help Prepare and stain samples for flow cytometry analysis.
• Operate laboratory instrumentation, including flow cytometers and related equipment, following established protocols.
• Help with the Processing of patient PBMCs for downstream applications, including singlecell RNA sequencing and bulk RNA analysis.
• Perform RNA extraction and other molecular biology procedures according to established methods.
• Assist with confocal microscopy experiments and routine laboratory assays.
• Record experimental results and maintain laboratory notebooks and electronic data files.
• Update Electronic Teams notebooks and onedrive files with the raw and processed/graphed data results
• For the Research and Development Manager.
• Assist in data compilation, quality control reviews, and preparation of research reports and
  presentations.

Laboratory Operations and Compliance

• Prepare laboratory reagents, buffers, and materials for research clincal immune monitoring activities.
• Maintain inventory of all supplies for assays related to immune monitoring as well as records and stock laboratory supplies.
• Ensure laboratory workspaces remain organized and compliant with laboratory safety standards.
• Participate in biosafety, chemical safety, and regulatory compliance activities.
• Assist with maintaining laboratory clinical batch records and documentation required for 
• inspections and and FDA/NIH audits.
• Maintain the clincal trial notebooks and the electronic teams folders for all clinical processing of
• Samples and keep all records, images and locations of clinical samples up to date weekly.
• Maintain the electronic spreasheets of Clincial patient samples, organized by sample type, (PBMC, Serum,
• Cell free DNA/RNA, CTC and tissue Biopsies) make sure all sampels are recorded and logged at intake during processing and when removed for immune monitoring assays.

  Training and Professional Development

• Attend laboratory meetings, seminars, and training sessions.
• Participate in continuing education opportunities to maintain technical competency.
• Assist with training new laboratory personnel on routine laboratory procedures as directed.

  Administrative and Departmental Support

• Provide support for laboratory inspections, audits, and accreditation activities.
• Assist with preparation of routine laboratory reports, meeting materials, and other administrative 
• documents.
• Participate in departmental activities and collaborative projects as assigned.

Expected Salary:

$22.17-$25.19 per hour

Required Qualifications:Associate's degree in an appropriate area and two years of related experience; or a high school diploma or equivalent and four years of related experience. Appropriate college course work or vocational/technical training may substitute at an equivalent rate for the required experience.

Preferred:

• Masters Degree and experience with Clinical patient sample processing and banking
• Some Experience in flow cytometry, Serum Elisa and other clinical assays.

Special Instructions to Applicants:

For consideration, please complete an application and include a cover letter, resume and the names and email addresses of three to five references. 

To claim veterans' preference, indicate the claim on the application and provide required documentation by uploading a DD-214 (or equivalent certification from the Department of Veteran Affairs) and any additional supporting documentation based on the type of claim.

Application must be submitted by 11:55 p.m. (ET) of the posting end date.

Health Assessment Required:Yes