Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Founding Software Engineer

$150k - $250k

Tamarind Bio

About Tamarind Bio We enable any scientist to access AI-powered drug discovery. Thousands of scientists from large pharma companies, top biotechs, and academic institutions use Tamarind to design protein drugs, improve industrial enzymes, and create cutting edge molecules that weren’t feasible until now. New AI models are quickly eclipsing physics-based tools in computational drug discovery. Scientists often struggle to fine-tune, deploy, and scale these models, leaving breakthroughs on the table. Tamarind provides a simple interface to the vast array of tools being released daily. About The Role We’re hiring three exceptional Founding Software Engineers to help us scale the computational biology platform that powers our drug discovery pipeline. In this role, you’ll collaborate closely with the founders to design, build, and scale our infrastructure, APIs, and web interface. You’ll own major pieces of our stack end-to-end — from architecture to deployment — and ship features that directly impact scientists and customers. You’ll be responsible for maintaining and expanding the core systems that underpin our computational biology tooling, ensuring reliability, scalability, and performance as we grow. This is a deeply collaborative and customer-facing role. You’ll work directly with users to understand their needs, translate feedback into product improvements, and deliver elegant solutions that accelerate their research. Techstack: Python, React, AWS (EC2, S3, DynamoDB), Docker, CUDA, Conda, TensorFlow/PyTorch; notebooks; bash/Slurm; APIs & web apps. Week in the Life Partner with founders on product decisions, scope experiments, and ship quickly Build/operate services (infra ML web) and iterate with customer feedback Mix of coding, design reviews, and practical deployment work Onsite expectation: Team currently onsite in SF ~5 days/week. Ideal Qualifications Adaptability and openness to work on diverse problems (e.g. batch HPC scaling, frontend development, automated fine-tuning…) AWS DevOps (DynamoDB, EC2, S3, docker, etc.) and MLOps (CUDA, Conda, Tensorflow, PyTorch) Front-end development (React/Vercel) Willingness to learn about biology-ML models Located in the SF Bay Area or able to relocate to the Bay Area Pluses Experience with AI/ML models across various architectures and environments Technology Our technology sits at the intersection of DevOps, MLOps, and Computational Biology. We deal with problems ranging from scaling ML inference on AWS for hundreds of GPUs to dissecting pdb files with Biopython. We deploy a wide range of open source ML models for customers, navigating between Docker containers, Colab notebooks, bash scripts, slurm jobs, and more. Our Interview Process We keep our process focused, transparent, and designed to give both sides a clear sense of fit. Recruiter Screen (15–30 minutes) — Virtual Meet with our recruiter to dive into your background, interests, and what you’re looking for next. We’ll also walk you through the company, team, and role. Technical Interview (90 minutes) — Virtual Co-Founder Interview (30 minutes): A conversation with Deniz Kavi (CEO & Co-founder) about product, collaboration, and how you approach building in an early-stage environment. Technical Deep Dive (60 minutes): A live coding and problem-solving session with Sherry Liu (CTO & Co-founder) or a member of our engineering team. Onsite (1 day) — San Francisco Spend a day with us working on a mini project and meeting the team. Compensation Range: $150K – $250K #J-18808-Ljbffr

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Founding Software Engineer in San Francisco, CA vacancy
  • $200k - $300k

     ...Job Description for Founding Software Engineer This position is provided by DGC Search. Your actual compensation will depend on your skills and experience — consult with your recruiter for more details. Base pay range $200,000.00/yr - $300,000.00/yr Direct message the... 
    Suggested
    Full time

    DGC Search

    San Francisco, CA
    3 days ago
  •  ...which is leading the charge in transforming observability for today's data-driven world is looking for seasoned software engineer to join them as a founding engineer. As the founding engineer you will lead the design and development of their Telemetry Data Management Platform... 
    Suggested
    Flexible hours

    Xcede

    San Francisco, CA
    1 day ago
  •  ...We’re searching for a founding engineer(s) who brings a mix of rapid iteration, meticulous craftsmanship, and an eagerness to dive into the...  ...1-3 (or more) years of experience building professional software with a very high quality bar. Ideally, you have demonstrable... 
    Suggested

    Decipher

    San Francisco, CA
    1 day ago
  •  ...Founding Low-Level Software Engineer Join Hire Hangar and work with fast-growing global companies while building a long-term career. Role Overview: We are seeking a Founding Low-Level Software Engineer to join an early-stage AI video infrastructure startup. The... 
    Suggested

    Hire Hangar

    San Francisco, CA
    3 days ago
  •  ...personalized AI assistant that understands everything about you and automatically arranges your trip for you. We're looking for a founding engineer to join the our team of 3-4. You'll tackle everything from optimizing LLM performance and building evals to integrating APIs... 
    Suggested
    Work at office
    Remote work
    Work from home
    Flexible hours
    Night shift

    Stardrift

    San Francisco, CA
    1 day ago
  •  ...simple interface to the vast array of tools being released daily. About the Role We're hiring three exceptional Founding Software Engineers to help us scale the computational biology platform that powers our drug discovery pipeline. In this role, you'll... 
    Relocation

    Tamarind Bio, Inc

    San Francisco, CA
    2 days ago
  • $150k - $200k

     ...Join to apply for the Founding Software Engineer role at Attune (YC X25) Join to apply for the Founding Software Engineer role at Attune (YC X25) Get AI-powered advice on this job and more exclusive features. This range is provided by Attune (YC X25). Your actual pay... 
    Full time

    Attune (YC X25)

    San Francisco, CA
    3 days ago
  • $160k - $210k

     ...We're building an AI-native platform to fix that, and 80+ practices are already running on it. THE ROLE This is a true founding-engineer seat. You'll work directly with therapists, ship real features that land in production, and own problems end-to-end - from the... 
    Relocation package

    Strategic Employment

    San Francisco, CA
    3 days ago
  • $90k - $120k

     ...Join to apply for the Founding Software Engineer role at Canvas AI (YC F24) Join to apply for the Founding Software Engineer role at Canvas AI (YC F24) This range is provided by Canvas AI (YC F24). Your actual pay will be based on your skills and experience — talk with... 
    Full time

    Canvas AI (YC F24)

    San Francisco, CA
    1 day ago
  • $130k - $200k

     ...About the Role A well-funded, seed-stage B2B SaaS startup in the supply chain integrations space is looking for a Founding Software Engineer to help shape the architecture, culture, and product direction of an agentic integrations platform. This is a high-ownership... 
    Work at office
    Visa sponsorship

    Clera

    San Francisco, CA
    17 hours ago
  •  ...Founding Software Engineer As a Founding Software Engineer, you'll have end-to-end ownership over projects pushing the frontier of AI evaluation. This isn't a narrow role. One week you might prototype a new RL environment from a research paper, the next you'll deploy... 
    Work at office
    Visa sponsorship

    RainesDev

    San Francisco, CA
    2 days ago
  •  ...beginning. You have the opportunity to: Join Onton as a Founding Engineer and set the foundation for our Engineering Team Design,...  ...heart who shares our values and is passionate about making software tools accessible to all, we want to hear from you. Onton... 
    Full time
    Work at office
    Local area
    Remote work
    Relocation
    3 days per week

    Onton

    San Francisco, CA
    4 days ago
  • $150k - $300k

     ...Future Leaders Wanted About the Role: We are seeking a Founding AI Engineer to join our early-stage, high-growth AI startup. This...  ...at Goliath Partners by 2x Sign in to set job alerts for “Software Engineer” roles. Mountain View, CA $145,000.00-$170,000.0... 
    Full time
    Summer work
    Internship

    Goliath Partners LP

    San Francisco, CA
    3 days ago
  • $5,000 per month

     ...database and PgDog is building its future. This isn’t an easy task, but it’s exciting and full of opportunities. As our first founding engineer, you will define the company. You’ll be given full autonomy and responsibility to build our products, including 0-to-1 projects... 
    Work at office
    Remote work

    PgDog

    San Francisco, CA
    1 day ago
  •  ...We’re seeking a Founding Software Engineer for an early staged AI & LLM startup based in San Francisco. About the Role Hands on experience developing technology using Python A builder of business logic with Web Framework such as Django and MySQL Experienced in Nginx,... 

    HMBL

    San Francisco, CA
    4 days ago
  •  ...interface for how enterprise employees interact with computers. Founded by two second-time founders, they're creating an AI agent that...  ...San Francisco. 2+ years of experience building production-level software Strong CS fundamentals and full-stack development experience... 
    Full time
    Immediate start

    Greylock Partners

    San Francisco, CA
    1 day ago
  •  ...customer support to order intake to lead qualifications. We are growing revenue like crazy and looking to hire a couple founding software engineers to help us stay afloat of current customer demand and also build out systems for the future. We are very excited about the... 
    Work experience placement
    Work at office

    Simple AI

    San Francisco, CA
    1 day ago
  •  ...stealth startup within the WealthTech space who specializes in building AI Native Portfolio Management tools in search for a Founding Engineer to join their organization. We are looking for an individual who has deep experience across the broader FinTech space (wealthtech... 

    Storm2

    San Francisco, CA
    18 hours ago
  •  ...scale faster. As a cornerstone of this team, we’re hiring 1 founding engineer in-person at our San Francisco office. Your Role As a founding...  ...s Head of Engineering. Skills We’re Looking For 3+ years of software development experience. Comfortable working across the stack... 
    Work at office
    Worldwide
    Shift work

    Kalinda (YC S25)

    San Francisco, CA
    1 day ago
  • $200k - $275k

     ...0,000.00/yr - $275,000.00/yr Managing Recruitment Consultant at Harnham US — Data, AI & Tech → Mid-West & South Atlantic Founding Software Engineer $200,000 to $275,000 + COMPANY A cutting-edge AI company is transforming creative strategy with AI-driven insights, leveraging... 
    Full time

    Harnham

    San Francisco, CA
    4 days ago
  • $130k - $170k

    Founding Engineer Join now to apply for the Founding Engineer role at Nowadays (YC S23) . Base pay range $130,000.00/yr - $170,000.00/yr About Nowadays Nowadays is the first AI platform for planning corporate events. Our AI can contact venues by email and phone to get... 
    Full time
    Work at office

    Nowadays (YC S23)

    San Francisco, CA
    2 days ago
  • $175k - $195k

     ...closed our seed round in November 2025 and our first commercial deployment launches in August. The Role We are hiring a Founding Software Engineer to own the software platform that turns our foundation model and IoT hardware into a usable product. As an early addition... 
    Full time
    Temporary work
    Work at office
    Immediate start

    The Electric Plant Co

    San Francisco, CA
    2 days ago
  • $160k - $220k

     ...About the job Founding Full-Stack Engineer Founding Full-Stack Product Engineer (AI-Native) On-Site | San Francisco | Full-Time $...  ...think clearly, and believe AI-native development changes how software should be built - keep reading. What Youll Own... 
    Full time
    H1b

    Transparent Search Group

    San Francisco, CA
    4 days ago
  •  ...and builders of everything from robots and race cars to software with millions of downloads . We're backed by the founders...  ...century. Dryft is powering the next. THE ROLE As Founding Fullstack Engineer , you'll be the brain behind Dryft's decision... 
    Relocation

    Dryft

    San Francisco, CA
    4 days ago
  • $200k - $300k

     ...Founding Full-Stack Engineer San Francisco | $200k-$300k + 0.2-0.5% Equity Most AI startups are building copilots. Our client is building...  ...built one of the most successful companies in logistics software, scaling it from startup to $500M+ ARR and a multi-billion... 
    Work at office

    Xpertalent

    San Francisco, CA
    5 days ago
  • $8,000 - $10,000 per month

     ...Join Hire Hangar and work with fast‑growing global companies while building a long‑term, remote career. Job Title: Founding Full‑Stack Engineer Location | On‑Site — San Francisco, CA Time Zone | PST Role Overview We are seeking a Founding Full‑Stack Engineer to join the... 
    Remote work

    Hire Hangar

    San Francisco, CA
    4 days ago
  • $175k - $275k

     ...Carma is hiring a Founding Full‑Stack Engineer to own product surfaces end‑to‑end — from ambiguous problem statement to scoped design to shipped enterprise software. Work on a TypeScript end‑to‑end stack (React, NestJS, PostgreSQL + Prisma, AWS). Ship a feature in the... 
    Day shift

    CertifiedDevs

    San Francisco, CA
    1 day ago
  • $100k - $150k

     ...Join to apply for the Founding Full Stack Engineer role at Text.ai (YC X25) 2 days ago Be among the first 25 applicants Join to apply for the Founding...  ...Engineering and Information Technology Industries Software Development Referrals increase your chances of interviewing... 
    Full time

    Text.ai (YC X25)

    San Francisco, CA
    3 days ago
  • $180k - $230k

     ...About the Role A well-funded, early-stage B2B SaaS startup in the AI-powered sales automation space is hiring its first Founding Engineer. You'll join the CTO as a core member of a tiny, high-caliber team and help set the technical culture for everyone who comes after... 
    Remote work

    Clera

    San Francisco, CA
    16 hours ago
  •  ...our clients Location: San Francisco (On-sit) Experience: 2-8 years Stage: Seed - Series B Role Type: Early hire / founding engineer Why This Role Exists You'll help build the core product from the ground up. This is a hands-on role for someone who... 

    Weekday AI

    San Francisco, CA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Founding Software Engineer. Be the first to apply!