Research Associate, Formulation Development (Contract)

GENERAL SUMMARY

4DMT is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients. The Company’s lead product candidate 4D-150 is designed to be a backbone therapy forming the foundation of treatment of blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF (aflibercept and anti-VEGF-C) with a single, safe, intravitreal injection, which substantially reduces the treatment burden associated with current bolus injections. The Company’s lead indication for 4D-150 is wet age-related macular degeneration, which is currently in Phase 3 development, and second indication is diabetic macular edema. The Company’s second product candidate is 4D-710, which is the first known genetic medicine to demonstrate successful delivery and expression of the CFTR transgene in the lungs of people with cystic fibrosis after aerosol delivery

MAJOR DUTIES & RESPONSIBILITIES:

Execute high-throughput, plate-based formulation screening, including formulation preparation, stability studies, sample testing, data analysis, and documentation. Support prefilled-syringe and other container/device compatibility assessments. Formulation analytics including but not limited to Size-Exclusion Multi-Angle Light Scattering, Differential Scanning Fluorimetry, Dynamic Light Scattering, pH and osmo testing. Collaboration with Upstream PD, Downstream PD and AD/QC

QUALIFICATIONS:

Education: Bachelors of Science Degree Experience: 0+ years of experience within the Biotech or similar industry Strong foundational laboratory skills, including accurate pipetting, solution preparation, weighing, basic laboratory calculations, and data organization using Excel. Hands‑on laboratory experience gained through academic research, internships, or industry. Experience with preformulation, formulation development, stability studies, drug‑product process development, or downstream process development is preferred. Experience with biologics, including proteins, antibodies, or AAV/gene therapy, is a plus. Other Qualifications/Skills: Applicant should possess a general competency in Microsoft based applications (e.g., Word, Excel, PowerPoint) Prior experience with statistical tools (e.g., JMP) or Prefilled Syringe development is preferred, but not required Travel: This role does not require travel outside of the main office. However, may provide opportunities to travel in future (e.g., to attend conferences or oversee outsourced activities) Physical Requirements and Working Conditions: Physical Activity - Repetitive motions: Making substantial movements (motions) of the wrists, hands, and/or fingers. Fingering: Picking, pinching, typing or otherwise working, primarily with fingers rather than with whole hand or arm as in handling. Talking: Expressing or exchanging ideas by means of the spoken word. Physical Requirements - Lifting up to 20 lbs, bending, lifting, twisting, ability to wear Personal Protective Equipment such as lab coat, goggles/glasses, and nitrile gloves Working Conditions - The worker is not substantially exposed to adverse environmental conditions (as in typical office or administrative work). Hourly compensation range: $39.00 - $45.00 / HOUR Please note, the base salary compensation range and actual salary offered to the final candidate depends on various factors: candidate’s geographical location, relevant work experience, skills, and years of experience. 4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran, and any other category protected under applicable federal, state, provincial and local laws. Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities #J-18808-Ljbffr Initial Therapeutics, Inc.