Principal Investigator / Medical Director - Clinical Research (San Antonio, TX)

Are you an experienced Principal Investigator (PI) or Medical Director (Investigator) looking for a new challenge in clinical research? We are seeking a highly qualified physician leader to join our San Antonio, TX office. This role requires hands-on oversight of clinical trials, ensuring participant safety, regulatory compliance, and collaboration with sponsors and CROs. This is a career-defining opportunity for a physician who is passionate about drug development, clinical trials, and advancing medical science . Key Responsibilities As the Principal Investigator/Medical Director , your role will include: Serving as Principal Investigator (PI) on multiple clinical research studies Providing medical oversight and ensuring patient safety throughout all trial phases Designing and reviewing protocols, amendments, and informed consent documents Ensuring strict adherence to FDA regulations, ICH-GCP guidelines, and IRB requirements Monitoring site performance, trial recruitment, and study timelines Supervising sub-investigators, coordinators, and research staff Collaborating with sponsors, CROs, regulatory agencies, and ethics boards Contributing to scientific publications, presentations, and clinical trial reports Qualifications We are looking for candidates with: MD, DO, or equivalent medical degree with an active medical license Board Certification in a relevant specialty (Oncology, Neurology, Internal Medicine, Endocrinology, or related) Minimum 5-10 years of clinical research experience (industry or academic) Previous role as Principal Investigator or Medical Director in clinical trials Strong knowledge of FDA regulations, Good Clinical Practice (GCP), and ICH guidelines Proven track record in leading multi-site or global clinical studies Preferred Skills Experience with early-phase (Phase I) clinical trials Knowledge of biostatistics, pharmacovigilance, and safety monitoring Ability to mentor junior investigators and research staff Excellent communication and leadership skills Strong scientific writing and publication background What We Offer Joining us as a principal investigator/medical director means: Competitive salary and benefits package Opportunity to lead cutting-edge clinical research in San Antonio Collaborative work with global sponsors and CROs Professional growth with support for conferences, publications, and leadership training Relocation assistance (if applicable) Job Location San Antonio, Texas, USA – Office-Based Application Process To apply, please submit the following documents: Updated Curriculum Vitae (CV) with detailed experience Cover letter explaining your interest in clinical research leadership Record of ongoing or past clinical trials (if available) Contact details of 2-3 professional references Why Join Us? This is not just another job —it’s an opportunity to: Influence the future of clinical research and drug discovery Contribute to life-changing therapies for patients worldwide Lead trials that meet the highest standards of safety, ethics, and compliance FAQs Q1. What is the salary range for a Principal Investigator / Medical Director in San Antonio, TX? Salary typically ranges from $180,000 - $250,000 per year , depending on experience and qualifications. Q2. Do I need prior PI experience? Yes, prior experience as Principal Investigator or Medical Director in clinical trials is required. Q3. Is this a remote role? No, this is an office-based position in San Antonio, Texas . Q4. What therapeutic areas are most relevant? Preferred areas include oncology, neurology, endocrinology, and internal medicine . Your email address will not be published. Required fields are marked * #J-18808-Ljbffr Pharmacareerinsider