Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior ML Scientist, Frontier LLMs for Drug Discovery

$158.1k - $293.5k

Genentech, Inc.

At Genentech Computational Sciences (gCS) Prescient Design, we are revolutionizing drug discovery with cutting-edge machine learning techniques. We are seeking talented engineers with a passion for building large-scale, distributed machine learning algorithms and systems that will transform the drug discovery process.

gCS Prescient Design is seeking an exceptional Senior Machine Learning Engineer to develop our LLM and AI product and enable the next generation of foundational research in machine learning for scientific discovery. We are looking for someone who is not only passionate about technical problem-solving but also has a proven track record of delivering innovative solutions in machine learning. The ideal candidate should have extensive experience in leading and managing a team of engineers and scientists, and be able to foster a culture of innovation, collaboration, and excellence across the broader gCS organization.

The group provides a dynamic and challenging environment for multidisciplinary research including access to heterogeneous data sources, close links to top academic institutions around the world, as well as collaborations with internal Genentech and Roche teams.

In this role, you will:

  • Participate in cutting-edge research in machine learning and methods development for scientific discovery, including large language models and drug discovery.
  • Develop and deploy machine learning models in production environments, working closely with other engineers to ensure scalability and reliability
  • Solve core engineering challenges including the design, implementation, and scaling of our machine learning algorithms.
  • Collaborate closely with cross-functional teams across both Prescient Design and gRED to solve complex problems in the life sciences.

Qualifications

  • MS or PhD in Computer Science, Statistics, related field or equivalent experience
  • 6+ years of industry experience in machine learning
  • Demonstrated success in technical leadership and in managing teams of machine learning engineers
  • Experience developing and deploying machine learning models in production environments
  • Strong programming skills in Python or another relevant language
  • Experience with deep learning frameworks such as PyTorch
  • An extensive track record of delivering innovative solutions in machine learning
  • Strong communication skills, with the ability to effectively communicate technical concepts to both technical and non-technical audiences as well as interfacing with scientific and engineering leadership
  • Experience collaborating with external scientific partners, such as academic institutions or industry research groups
  • A passion for solving complex technical problems and a commitment to staying up-to-date with the latest developments in machine learning.

gCS

Who We Are

Genentech, a member of the Roche Group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

The expected salary range for this position based on the primary location of South San Francisco or New York City is $158,100 - 293,500 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Genentech is an equal-opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

#J-18808-Ljbffr
Vacancy posted 5 hours ago
Similar jobs that could be interesting for youBased on the Senior ML Scientist, Frontier LLMs for Drug Discovery in Los Angeles, CA vacancy
  • $158.1k - $293.5k

     ...Prescient Design, we are revolutionizing drug discovery with cutting‑edge machine learning...  ...Prescient Design is seeking an exceptional Senior Machine Learning Engineer to develop...  ...leading and managing a team of engineers and scientists, and be able to foster a culture of... 
    Senior

    Genentech, Inc.

    Los Angeles, CA
    6 hours ago
  • Relativity is seeking a Staff Applied Scientist to tackle the hardest document-vision problems...  ...for flagship AI systems and mentor senior scientists, working across engineering and...  ...environment. You bring 6+ years of applied AI/ML and a PhD or Master’s in a quantitative... 
    Senior

    Relativity

    Los Angeles, CA
    3 days ago
  • $175k - $200k

    Launch Potato is seeking a Data Scientist to lead the data science engine for insurance. You will be responsible for building models that...  ...years of experience in applied data science, particularly with ML solutions in AWS. Offered salary ranges from $175,000 to $200,00... 
    Senior
    Remote work

    Launch Potato

    Los Angeles, CA
    2 days ago
  • A cutting-edge identity verification firm in Los Angeles is seeking a Staff Applied ML Scientist to develop core products aimed at identifying fraud in financial risk. The ideal candidate has 6+ years of relevant experience or a PhD, with strong capabilities in data science... 
    Senior
    Remote job

    SentiLink

    Los Angeles, CA
    2 days ago
  • $166.55k - $266.48k

    As an Applied Scientist on our Global Insights and Analytics team, you will play a key role in researching and developing cutting edge machine...  ..., by thoroughly understanding model diagnostics, focusing on ML engineering aspects to deploy scalable solution and summarize... 
    Senior
    Work experience placement

    Capital Group

    Los Angeles, CA
    2 days ago
  • $200k - $240k

     ...or in‑office by design. For example, our engineering team in India works primarily from our Gurugram office. Role As a Senior Applied ML Scientist at SentiLink, you will build our core products: models that identify fraudsters and also advance our growing suite of products... 
    Senior
    Work experience placement
    Live in
    Work at office
    Remote work
    Home office
    Flexible hours

    SentiLink

    Los Angeles, CA
    2 days ago
  • $80.3k - $131.1k

     ...Senior Associate Scientist, R&D Chemistry Job Description We are currently seeking a synthetic organic chemist for the R&D (Research &...  ...in supporting Regeneron small molecule antibody-conjugate drug discovery capabilities, providing an important link with the company... 
    Senior

    Regeneron

    Hawthorne, CA
    a month ago
  •  ...-to-end visibility into AI agents, LLM pipelines, and ML-powered applications — from user interaction through model...  ...here are deep and largely unsolved. As a Research Scientist at AnoSys, you will work at the frontier of this problem space. You will design, prototype, and... 
    Immediate start

    AnoSys Technologies, Inc

    Los Angeles, CA
    4 days ago
  • $228.7k - $306.7k

    Job Posting Title:Senior Principal Machine Learning Engineer, Ad PlatformsReq...  ..., technologists, data scientists, and more - all working to...  ...skills to unblock and guide our ML and Research teams to create scalable...  ...knowledgeDeep expertise in:LLMs and OpenAI GPT models, Claude,... 
    Senior
    Full time

    Hulu

    Santa Monica, CA
    4 days ago
  • $185k

     ...Senior Data ScientistCompany: STEVEN.COMReporting To: Head Of Data...  ...OutcomesDesign, build, and deploy ML models and AI systems powering...  ...datasets.Work hands-on with LLMs and foundation models - fine-...  ...foundation models and applying frontier ML research to real business... 
    Senior

    FlightStory

    Los Angeles, CA
    3 days ago
  • $80.3k - $131.1k

     ...Sr. Associate Scientist (Peptidomimetic Purification), R&D Chemistry We are currently seeking a lab-centric peptide purification...  ...a key role in Regeneron’s peptidomimetic antibody-conjugate drug discovery capabilities to enable seamless combination with the company’... 
    Senior

    Regeneron

    Hawthorne, CA
    more than 2 months ago
  • $163.2k - $220.8k

     ...Wilson Sonsini is looking for a Senior AI Security Engineer to join the...  ...Engineering and Operations, sits at the frontier of AI infrastructure and...  ...jailbreaking, data exfiltration via LLMs, model inversion, and supply chain attacks on AI/ML dependenciesEngineer secure data... 
    Senior
    Full time
    Work experience placement
    Remote work
    Worldwide
    Shift work

    Wilson Sonsini Goodrich & Rosati

    Los Angeles, CA
    5 days ago
  •  ...community.Job SummaryLIGO Laboratory (the Laser Interferometer Gravitational-wave Observatory) seeks a highly motivated and skilled Senior Scientist to join its team with experience in research, design and problem solving in a collaborative environment. LIGO Laboratory is a... 
    Senior

    California Institute of Technology

    Pasadena, CA
    3 days ago
  • $157k - $235k

     ...Engineering, Strategy, and Sales to ensure Snap’s ad products are effective, efficient, and customer‑centric.We’re looking for a Senior Marketing Scientist to join our Marketing Science team at Snap Inc!What you’ll do:Be the primary driver of performance improvement across key... 
    Senior
    Full time
    Work experience placement
    Live in
    Work at office
    Local area

    Snap

    Los Angeles, CA
    3 days ago
  • $167.1k - $226.1k

    We are seeking an Applied Scientist to join Amazon Robotics, Compass Team. In this role, you will own the development of safe legged locomotion...  ...legged locomotion • Publish research at top-tier robotics and ML venues and contribute to Amazon's scientific reputation in... 
    Senior
    Full time
    Temporary work
    Seasonal work
    Local area
    Flexible hours

    Amazon

    Pasadena, CA
    2 days ago
  • Netflix's Creative Technology Research team in Los Angeles seeks a senior machine learning researcher to build foundational image and video generation models for filmmaking. You will own model architecture, train on large distributed systems, and shape data strategies... 
    Senior

    Workman Labs

    Los Angeles, CA
    2 days ago
  • $115k - $135k

     ...Offices globally Our Opportunity We are currently seeking a Senior Geologist for our Civil & Structural Engineering Practice in...  ...multiple group projects and to interact with other engineers, scientists, administrative staff, and clients Degrees, experience, or... 
    Senior
    Work at office
    Remote work
    Flexible hours

    Exponent

    Los Angeles, CA
    1 day ago
  •  ...of a global team of over 50,000 planners, designers, engineers, scientists, digital innovators, program and construction managers and...  ...world. Join us.Job DescriptionAECOM is seeking an experienced Senior Ecologist to join our Southern California Natural Resources Group... 
    Senior
    Contract work
    Work at office
    Local area
    Worldwide
    Flexible hours

    AECOM

    Los Angeles, CA
    2 days ago
  • $120k - $150k

     ...are looking for passionate, driven individuals to join our team focused on Delivering Solutions and Improving Lives.We are seeking a Senior Water Resources/Water Quality Project Manager to join our team of Water Resources experts in Torrance, CA. This senior position is... 
    Senior
    Full time
    Work at office
    Local area
    Remote work

    nv5 global

    Los Angeles, CA
    5 days ago
  •  ...Senior Engineering Geologist (Supervisory)The Los Angeles Regional Water Quality Control Board's Site Cleanup Program has an opening for a Senior Engineering Geologist (Supervisory). The position is in our office at 320 West 4th Street 2nd Floor, Los Angeles, CA 90013... 
    Senior
    Work at office

    California State Jobs

    Los Angeles, CA
    1 day ago
  • $208.25k - $354.02k

     ...can succeed as an Artificial Intelligence Scientist IV at Capital Group.” As an Artificial...  ...applications using Large Language Models (LLMs) and Agentic AI, such as conversational assistants...  ...a talented team of both junior and senior applied scientists, fostering growth and... 
    Full time
    Temporary work
    Work experience placement
    Local area
    Flexible hours

    Capital Group

    Los Angeles, CA
    3 days ago
  • $93.8k - $140.8k

     ...demonstrable experience in southern California and elsewhere. As a Senior-level Biologist with Stantec, you will work in a highly dynamic...  ...’s license and good driving record.A medical physical and/or drug and alcohol screening may be required for some project assignments... 
    Senior
    Full time
    Temporary work
    Part time
    Casual work
    Work at office
    Local area
    Flexible hours
    Night shift

    Stantec

    Los Angeles, CA
    5 days ago
  •  ...StatesCompany: Providence Health & ServicesPosted: 2026-08-12Providence St. Joseph Medical Center in Burbank, CA is seeking a Senior Medical Laboratory Scientist for a full-time role with 8-hour, variable shifts. The incumbent will assist the Clinical Specialist in supervising a... 
    Senior
    Full time
    Shift work

    Providence Health & Services

    Burbank, CA
    2 days ago
  •  ...Merck & Co. is looking for a Senior Medical Science Liaison for Movement Disorders, based in Los Angeles, CA. This role focuses on generating insights in support of Lundbeck’s NeuroRare initiatives in multiple system atrophy. The ideal candidate will establish partnerships... 
    Senior

    Merck & Co.

    Los Angeles, CA
    6 hours ago
  • Senior Medical Laboratory Scientist at Providence St. Joseph Medical Center in Burbank, CA. This position is full-time and will work 8-hour, variable shifts.Providence St. Joseph Medical Center is proud to be Magnet recognized, the nation’s highest recognition for nursing... 
    Senior
    Minimum wage
    Full time
    Local area
    Shift work

    Providence Health & Services

    Burbank, CA
    2 days ago
  •  ...Senior DevOps Platform Engineer Help Us Build Scalable AI Solutions for Life Sciences...  ...power real-world AI workflows across drug discovery, clinical development, and commercial operations...  ...traffic routing. Experience with AI/ML, HPC, or other data- and compute-... 
    Senior
    Full time
    Remote work

    Salt Ai

    Los Angeles, CA
    9 days ago
  • Arcturus in Los Angeles is looking for Senior Scientists/Engineers to innovate in carbon nanomaterials and advanced manufacturing. This role involves executing experiments, analyzing data, and collaborating with technical leads to ensure progress in product development.... 
    Senior

    Arcturus

    Los Angeles, CA
    3 days ago
  • Infinite Computing Systems in Sylmar, CA, is seeking a highly experienced individual to perform validation for sterilization processes using Ethylene Oxide and Radiation methods. This role involves supporting R&D for new products and ensuring compliance with corporate policies...
    Senior

    Infinite Computing Systems

    Los Angeles, CA
    6 days ago
  • Skydrop is seeking a Senior Research Scientist to design quantum algorithms and QEC workflows that underpin product offerings and external demonstrations. You will collaborate with research and engineering teams to produce high‑impact research, publications, and to translate... 
    Senior

    Skydrop

    Los Angeles, CA
    6 days ago
  • $80k - $84k

    The California Institute of Technology is seeking a Payment Services Analyst to manage complex payment requests and ensure compliance with tax regulations. Candidates should hold a Bachelor's degree and have at least 7 years of experience in financial operations. This ...
    Senior

    California Institute of Technology

    Pasadena, CA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior ML Scientist, Frontier LLMs for Drug Discovery. Be the first to apply!