Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Registered Nurse (RN) - PRN

TRITAL Systems

About the Role

We are seeking skilled, compassionate, and dependable Registered Nurses for PRN assignments at hospitals and healthcare facilities in Columbia, Missouri.

We are recruiting qualified RNs across multiple clinical specialties. Candidates will be considered based on their nursing experience, demonstrated competencies, current credentials, and ability to meet the requirements of their assigned units.
Nursing Specialties We Are Hiring For
  • RN - Neuro Stepdown/SDU: Provide neurological monitoring and intermediate-level care for patients requiring increased observation and nursing intervention.
  • RN - Medical-Surgical (Med-Surg): Deliver nursing care to patients with medical conditions, postoperative needs, and varying levels of acuity.
  • RN - Operating Room (OR): Provide perioperative nursing care and support safe surgical procedures.
  • RN - PACU (Pediatric): Provide postoperative recovery care and monitoring for pediatric patients following anesthesia.
  • RN - Progressive Care Unit (PCU): Care for patients requiring intermediate-level monitoring and nursing interventions.
  • RN - Pediatric Intensive Care Unit (PICU): Provide specialized critical care for critically ill or injured infants, children, and adolescents.
  • RN - Pre-Op: Perform preoperative assessments, prepare patients for procedures, and support surgical readiness.
  • RN - Telemetry (Tele): Monitor cardiac rhythms, assess patients, and identify changes requiring clinical intervention.
  • RN - OR General: Provide perioperative nursing support for general surgical procedures.
  • RN - OR Circulator: Coordinate intraoperative patient safety, surgical documentation, and collaboration with the surgical team.
  • RN - Intensive Care Unit (ICU): Deliver critical care to unstable and critically ill patients requiring advanced monitoring.
  • RN - Emergency Department/Emergency Room (ED/ER): Provide emergency assessments, triage as assigned, stabilization, and urgent nursing interventions.
  • RN - Behavioral Health Services (BHS): Provide psychiatric and behavioral health nursing care, therapeutic communication, and patient safety monitoring.
Responsibilities

Responsibilities vary by specialty and assigned facility and may include:
  • Assessing patients and developing, implementing, and evaluating individualized nursing care plans.
  • Monitoring vital signs, symptoms, laboratory findings, and changes in clinical condition.
  • Administering medications and treatments according to provider orders and facility policies.
  • Recognizing clinical deterioration and escalating concerns promptly.
  • Performing nursing procedures within the RN scope of practice and demonstrated competency.
  • Maintaining accurate patient records and electronic health documentation.
  • Collaborating with physicians, nurses, and interdisciplinary healthcare teams.
  • Educating patients and families regarding treatment, recovery, medications, and discharge instructions.
  • Following infection prevention, medication safety, patient identification, and confidentiality standards.
  • Participating in shift handoffs, care coordination, and transitions of care.
  • Responding to emergencies and following applicable rapid response and escalation procedures.
  • Maintaining a safe, respectful, and patient-centered care environment.
OR nurses may perform perioperative duties and surgical safety procedures. Pre-Op and PACU nurses support surgical preparation and recovery. ICU, PICU, PCU, SDU, and Telemetry nurses provide care appropriate to patient acuity and monitoring needs. ED/ER and BHS nurses follow their respective emergency and behavioral health protocols.

Schedule and Work Environment

This is a PRN position offering shifts based on facility staffing requirements, patient census, unit needs, and confirmed availability. Shifts may include days, evenings, nights, weekends, and holidays.

Candidates should be comfortable working in fast-paced clinical environments, managing changing patient needs, following facility-specific protocols, and collaborating with multidisciplinary teams.

PRN scheduling does not guarantee a specific number of hours or shifts. Nurses are expected to maintain reliable attendance, communicate availability, and fulfill accepted assignments.

Ideal Candidate

The ideal candidate is clinically competent, compassionate, adaptable, and committed to safe, high-quality patient care. They demonstrate sound clinical judgment, effective communication, accurate documentation, and the ability to respond appropriately to changing patient conditions.

Applicants should identify their relevant specialties, clinical experience, current certifications, and shift availability. All required credentials and specialty competencies must be verified before placement.

Requirements

Required Qualifications
  • Current, active Registered Nurse (RN) license valid for practice in Missouri, or other legally accepted authorization to practice in Missouri.
  • Nursing education that meets applicable licensure requirements.
  • Relevant clinical experience and demonstrated competency for the assigned specialty.
  • Current Basic Life Support (BLS) certification as required by the facility.
  • Strong clinical assessment, critical-thinking, communication, and documentation skills.
  • Knowledge of medication safety, infection prevention, patient confidentiality, and facility protocols.
  • Ability to recognize clinical deterioration and respond appropriately.
  • Willingness to complete required onboarding, competency assessments, background checks, and credential verification.
  • Ability to meet the essential functions of the position, with reasonable accommodation where applicable.
  • Reliable transportation to assigned facilities in Columbia, Missouri.
  • Reliable attendance and availability for accepted PRN shifts.
Specialty-Specific Qualifications
  • Neuro Stepdown/SDU, PCU, and Telemetry: Relevant monitoring experience; ACLS certification when required.
  • Medical-Surgical: Medical-surgical or acute care nursing experience.
  • OR General and OR Circulator: Perioperative experience, sterile technique, and surgical safety knowledge.
  • Pediatric PACU: Pediatric post-anesthesia recovery experience and PALS certification when required.
  • PICU: Pediatric critical care experience and applicable pediatric life-support certifications.
  • Pre-Op: Experience with preoperative assessment, patient preparation, and perioperative safety.
  • ICU: Critical care nursing experience and ACLS certification when required.
  • ED/ER: Emergency nursing experience and applicable emergency care certifications, as required by the facility.
  • BHS: Behavioral health nursing experience and knowledge of therapeutic communication, de-escalation, and patient safety.
Preferred Qualifications
  • Previous PRN, float pool, travel nursing, or multi-facility experience.
  • Specialty certifications such as CCRN, CEN, CNOR, PCCN, or other relevant credentials, where applicable.
  • Familiarity with electronic health records and clinical documentation systems.
  • Strong teamwork, adaptability, and professional communication skills.
  • Availability for additional shifts, including weekends and holidays.
Certification and experience requirements vary by specialty and facility. All applicable Missouri license requirements, credentials, and unit-specific competencies must be verified before placement.

Benefits

Why Consider This PRN Opportunity?
  • Flexible scheduling: PRN shifts based on facility needs and your availability.
  • Specialty-focused assignments: Opportunities aligned with your clinical experience and competencies.
  • Professional development: Maintain and expand your nursing experience across eligible specialties.
  • Collaborative environment: Work alongside physicians, nurses, and multidisciplinary healthcare teams.
  • Varied clinical experience: Potential assignments across acute care, critical care, perioperative, emergency, and behavioral health settings.
  • Additional shifts: Opportunities may be available based on staffing requirements.
  • Meaningful patient care: Contribute to patient safety, recovery, and quality outcomes.

Benefits, compensation, and additional opportunities depend on the employer, facility, and assignment. PRN positions may not include the same benefits as full-time positions.
Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Registered Nurse (RN) - PRN in Columbia, MO vacancy
  •  ...lasting relationships with your patients? If those pique your interest, then KabaFusion might be the place for you! Why do Registered Nurses want to work here? At KabaFusion, we are committed to building a culture of collaboration and teamwork where we put the needs... 
    Relief
    Flexible hours
    Shift work

    KabaFusion

    Columbia, MO
    1 day ago
  •  ...TOPS Surgical Specialty Hospital is hiring a PRN PACU Registered Nurse! Welcome to TOPS Surgical Specialty Hospital! TOPS Surgical Specialty...  ...compassionate PRN PACU Registered Nurse to join our team. As a PACU RN you will play a crucial role in delivering exceptional... 
    Relief

    United Surgical Partners

    Columbia, MO
    1 day ago
  • $38 - $49 per hour

     ...CenterPointe Hospital is looking for compassionate nurses to provide exceptional patient care at...  ...to apply! Responsibilities REGISTERED NURSE ESSENTIAL FUNCTIONS Provide and...  ...Must possess a current Registered Nurse (RN) license as required by Missouri or be... 
    Relief
    Flexible hours
    Shift work

    Acadiana Treatment Center

    Columbia, MO
    3 days ago
  • $33 - $45 per hour

     ...Registered Nurse Career Opportunity Sign-On Bonus of $7,500.00 for full-time position Full-Time, Part-Time and PRN openings Salary Range - $33 - $45 per hour based on experience All...  ...patients. Qualifications Valid RN licensures as required by state... 
    Relief
    Hourly pay
    Full time
    Part time
    Relocation package
    All shifts
    Flexible hours
    Shift work
    Night shift
    Day shift

    HealthSouth

    Columbia, MO
    1 day ago
  • $71.64k - $107.46k

     ...number: 1062638 Job category: Nursing Explore opportunities with...  .... Growing together. As the Registered Nurse Case Manager, you will...  ...are hiring for full-time and PRN nurses. We're offering a $7...  ...~ Current and unrestricted RN licensure in the state of practice... 
    Relief
    Minimum wage
    Full time
    Work experience placement
    Local area
    Relocation package

    UnitedHealth Group

    Columbia, MO
    3 days ago
  • ???? PRN Registered Nurse (RN) Pediatric Day Healthcare Center ???? West Palm Beach, FL 2005 Vista Parkway, Suite 110A West Palm Beach, FL 33411 ? No Experience Required | New Grads Welcome ? Daytime Hours Only | No Nights, Weekends, or Holidays... 
    Relief
    Temporary work
    Monday to Friday
    Flexible hours
    Day shift
    2 days per week

    Aveanna Healthcare LLC

    Columbia, MO
    20 hours ago
  • $36.4 per hour

     ...Shift : Monday - Friday days PRN Work Arrangement : On-Site Department : Operating...  ...looking for a dedicated and compassionate Nurse, OR/Recovery to join our esteemed surgical...  ...Missouri Board of Nursing RN or Nurse Licensure Compact multi-state RN.... 
    Relief
    Hourly pay
    Monday to Friday
    Shift work

    University of Missouri Health Care

    Columbia, MO
    1 day ago
  •  ...Registered Nurse Opportunities Looking for a challenging and rewarding job where you'll feel appreciated and respected? We're hiring Full-Time Registered Nurses (RN), days & nights, and PRN and charge nurses for both days & nights as well as for both days & nights... 
    Relief
    Full time
    Local area
    Night shift

    Landmark Hospitals

    Columbia, MO
    4 days ago
  •  ...Gifted Healthcare is an award-winning travel nursing agency that offers nursing contracts at...  ...all overtime hours worked (excluding local, PRN, CA, Govt assignments). Weekly Pay -...  ...and treatment of patients. MedSurg RN job responsibilities include, but are not... 
    Relief
    Hourly pay
    Weekly pay
    Temporary work
    Local area
    Shift work
    Night shift

    Therapia Staffing

    Columbia, MO
    2 days ago
  • $70k - $80k

     ...Sign On Bonus! Full Time, Part Time, & PRN Skilled Nursing Visits Columbia, MO and surrounding...  ...Range: $70,000 - $80,000 As a Phoenix RN, you will be the first point of contact...  ...electronic charting. Requirements Current Registered Nurse or Licensed Practical Nurse... 
    Relief
    Full time
    Part time
    Relocation package

    Phoenix Home Care and Hospice

    Columbia, MO
    2 days ago
  • $2,279 - $2,532 per week

     ...Local CVICU Registered Nurse (RN) Job in Columbia, MO $2,279 - $2,532/week CVICU Local 1 Opening 13 weeks 10/04/26 to 01/03/27...  ...assignments for all overtime hours worked (excluding local, PRN, CA, Govt assignments). Weekly Pay We pay you weekly so you... 
    Relief
    Hourly pay
    Weekly pay
    Temporary work
    Local area
    Shift work
    Night shift

    Gifted Healthcare

    Columbia, MO
    4 days ago
  • $1,732 - $2,198 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Columbia, MO Agency: Envista Resources Pay: $1,732 to $2,198 per week Shift...  ...offer a comprehensive range of staffing solutions, including PRN, local contract, correctional, and nationwide travel... 
    Relief
    Full time
    Contract work
    Local area
    Immediate start
    Shift work

    TravelNurseSource

    Columbia, MO
    1 day ago
  • $36.4 per hour

     ...Staff Nurse Inpatient Float Pool Shift: Various shifts requires at least 24 hours (2 12-hour shifts) in a 6-week schedule period with...  ...delivering exceptional patient care. If you are a compassionate RN with a knack for quick thinking and a desire to make a meaningful... 
    Relief
    Hourly pay
    Price work
    Shift work
    Night shift
    Rotating shift
    Weekend work
    Afternoon shift

    University of Missouri Health System

    Columbia, MO
    4 days ago
  • $2,024 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Columbia, MO Agency: PRN Healthcare Pay: $2,024 per week Shift Information: Days - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 8/3/2026 About the Position Your adventure... 
    Relief
    Full time
    Contract work
    Local area
    Shift work

    PRN Healthcare

    Columbia, MO
    1 day ago
  • $2,024 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Columbia, MO Agency: PRN Healthcare Pay: $2,024 per week Shift Information: Days - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 8/3/2026 About the Position TravelNurseSource... 
    Relief
    Daily paid
    Full time
    Contract work
    Locum
    Local area
    Shift work

    TravelNurseSource

    Columbia, MO
    1 day ago
  •  ...during shiftsEmployee recognition and appreciation programsBenefits may vary based on full-time, part-time, or PRN status.Your Role as the Licensed Practical Nurse (LPN)Assisted LivingAs a Licensed Practical Nurse (LPN) in our Assisted Living community, you'll have a... 
    Relief
    Full time
    Part time
    Work at office

    Parkside Memory Care

    Columbia, MO
    20 hours ago
  • $48 per hour

     ...you're tired of having no control over your schedule or just want to earn more money, PRN shifts could be what you're looking for! ShiftKey enables independent Licensed Practical Nurses like you to bid on per diem LPN shifts posted by a vast network of Healthcare... 
    Relief
    Weekly pay
    Daily paid
    Extra income
    Flexible hours
    Shift work
    Night shift

    Shift Key

    Columbia, MO
    1 day ago
  •  ...Registered Nurse "Compassionate Care for Meaningful Lives." Overview Position Type: Full-Time...  ...and compassionate Registered Nurse (RN) to lead our health-related services. In...  ...on medical protocols (seizure, choking, PRN, medication administration, etc.) and specific... 
    Relief
    Full time

    Impact Support Services

    Columbia, MO
    20 hours ago
  • $36.4 per hour

     ...MU Healthcare is looking for a dedicated and compassionate Nurse, OR/Recovery to join our esteemed surgical team. We seek an individual...  .... REQUIRED QUALIFICATIONS Missouri Board of Nursing RN or Nurse Licensure Compact multi-state RN. When primary state of... 
    Relief
    Hourly pay
    Shift work

    University of Missouri Health Care

    Columbia, MO
    1 day ago
  • $32 - $36 per hour

     ...- $36 / per hour Maxim Healthcare in Columbia is hiring for a Licensed Practical Nurse (LPN) to work with Pediatric and/or Adult patients in their own homes. Full Time, Part Time, PRN positions available. Why Join Maxim: Competitive pay & weekly paychecks Health, dental... 
    Relief
    Hourly pay
    Weekly pay
    Full time
    Temporary work
    Part time
    Relocation package

    Maxim Healthcare Service

    Columbia, MO
    1 day ago
  •  ...urban culture, outdoor beauty, and Midwestern hospitality, travel nurse jobs in Missouri provide the perfect balance of professional opportunity and personal adventure.Your adventure starts here with PRN Healthcare!Take control of your career with a travel contract or local... 
    Relief
    Contract work
    Local area
    Night shift

    PRN Healthcare Services

    Columbia, MO
    3 days ago
  • $2,087 - $2,150 per week

     ...MS/Tele RN Location: Columbia, MO Weekly Rate: $2,087 - 2,150 Shift: Nights,...  ...beauty, and Midwestern hospitality, travel nurse jobs in Missouri provide the perfect balance...  ...and personal adventure. Why PRN Healthcare? Your adventure starts here... 
    Relief
    Contract work
    Local area
    Shift work
    Night shift

    PRN Healthcare Services

    Columbia, MO
    4 days ago
  • $32 - $50 per hour

     ...RN Charge Nurse – Critical Care Looking for a challenging and rewarding career where you'll...  ...multidisciplinary team. If you are an experienced Registered Nurse who enjoys leading others,...  ...time = 3 shifts/week (12-hour shifts). PRN = as little as 1 shift every 2 weeks.... 
    Relief
    Full time
    Local area
    Relocation package
    Shift work
    Night shift
    Weekend work

    Landmark Hospitals

    Columbia, MO
    4 days ago
  •  ...RN Homecare Columbia, Missouri Pay: $32 - $36 / per hour Weekly Pay | Flexible Scheduling...  ...Maxim Healthcare and provide skilled 1:1 nursing care in patients' homes. Enjoy a...  ...Details: Full-time, part-time, and PRN opportunities available Day, evening, and... 
    Relief
    Hourly pay
    Weekly pay
    Full time
    Part time
    Work at office
    Local area
    Flexible hours
    Night shift
    Day shift
    Afternoon shift

    Maxim Health Systems

    Columbia, MO
    3 days ago
  •  ...Centerpointe Columbia Hospital Admissions RN Opportunity We are seeking a dedicated and compassionate Registered Nurse (RN) to join our admissions team at CenterPointe Columbia Hospital. As an Admissions RN, you will play a crucial role in ensuring a smooth and efficient... 
    Relief
    Local area

    Acadiana Treatment Center

    Columbia, MO
    3 days ago
  • $2,783 - $2,853 per week

     ...Interventional Radiology RN Location: Columbia, MO Weekly Rate: $2,783 - 2,853...  ...beauty, and Midwestern hospitality, travel nurse jobs in Missouri provide the perfect balance...  ...adventure. Your adventure starts here with PRN Healthcare! Take control of your career... 
    Relief
    Contract work
    Local area
    Shift work

    PRN Healthcare Services

    Columbia, MO
    20 hours ago
  •  ...unique mix of urban culture, outdoor beauty, and Midwestern hospitality, travel nurse jobs in Missouri provide the perfect balance of professional opportunity and personal adventure.Why Prn Healthcare?Your adventure starts here with PRN Healthcare!Take control of your career... 
    Relief
    Contract work
    Local area

    PRN Healthcare Services

    Columbia, MO
    3 days ago
  •  ...Homecare Nurses Needed for Morning and Afternoon Split Shift in Columbia, MO Morning and...  ...experience required! Full-time, Part-time, and PRN Hours Available Immediately! Flexible...  ...Bonus Program Paid Vacation 24/7 RN Support Health Benefits including Medical... 
    Relief
    Weekly pay
    Daily paid
    Full time
    Part time
    Immediate start
    Flexible hours
    Day shift
    Afternoon shift

    Advantage Nursing Service

    Columbia, MO
    1 day ago
  •  ...unique mix of urban culture, outdoor beauty, and Midwestern hospitality, travel nurse jobs in Missouri provide the perfect balance of professional opportunity and personal adventure.Why PRN Healthcare?Your adventure starts here with PRN Healthcare!Take control of your career... 
    Relief
    Contract work
    Local area

    PRN Healthcare Services

    Columbia, MO
    3 days ago
  •  ...Licensed Practical Nurse Looking for a challenging and rewarding job where...  ...? We're hiring fulltime and PRN Licensed Practical Nurse. Our team of Registered Nurses excel in their field and utilize...  ..., under the supervision of an RN (Registered Nurse). Continually... 
    Relief
    Full time
    Temporary work
    Local area

    Landmark Hospitals

    Columbia, MO
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Registered Nurse (RN) - PRN. Be the first to apply!