Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Associate Principal Scientist, Immunology Discovery

$142.4k - $224.1k

Merck

Merck seeks an Associate Principal Scientist in Immunology Discovery to lead early-to-late stage drug discovery programs for inflammatory and autoimmune diseases. The role involves directing cross-functional teams, designing innovative research strategies, and advancing therapeutic candidates from discovery through clinical development in San Diego.

Responsibilities

  • Define and execute drug discovery immunology project strategies across multiple programs
  • Lead cross-functional teams to advance therapeutic candidates from early discovery to clinical stage
  • Present program recommendations and strategic decisions to senior governance committees
  • Design, execute, and interpret complex in vitro and ex vivo immunology studies independently
  • Identify and implement innovative approaches and technologies to increase program efficiency and productivity

Requirements

  • Ph.D. in immunology, cell biology, or related biomedical science with 5+ years experience
  • Demonstrated leadership of early-to-late stage discovery programs in matrixed environments
  • Strong immunology background with knowledge of immune-mediated diseases in gastroenterology, rheumatology, or dermatology
  • Expertise in cell culture, flow cytometry, immunoassays, and molecular biology techniques
  • Proficiency with data analysis tools including Excel, GraphPad Prism, and FlowJo
  • Strong cross-functional collaboration and mentoring abilities
  • Excellent communication of complex data and program strategies to diverse audiences
Vacancy posted 13 days ago
Similar jobs that could be interesting for youBased on the Associate Principal Scientist, Immunology Discovery in San Diego, CA vacancy
  • $142.4k - $224.1k

     ...improving the lives of patients. The Discovery Immunology organization is developing and advancing...  ...needs. We are seeking anAssociate Principal Scientistwith strong background in Immunology...  ...mentorship to less experienced scientists to ensure a culture of scientific rigor... 
    Principal
    For contractors
    Local area
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co. , Inc.

    San Diego, CA
    1 day ago
  • $142.4k - $224.1k

     ...and dedication to improving the lives of patients. The Discovery Immunology organization is developing and advancing innovative...  ...address significant unmet medical needs. We are seeking an Associate-Principal Scientist - with strong background in Immunology and experience... 
    Principal
    Full time
    For contractors
    Local area
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    San Diego, CA
    13 days ago
  • $142.4k - $224.1k

     ...Associate Principal Scientist position in immunology discovery at Merck focused on leading translational research activities. The role involves designing experiments with primary immune cells and patient samples, developing disease models, and generating decision-enabling... 
    Principal

    Merck

    San Diego, CA
    21 days ago
  • $142.4k - $224.1k

     ...Job Description The Associate Principal Scientist will lead translational discovery activities through strong expertise in immune cell biology, human disease...  ...experiments to validate therapeutic targets in immunology, inflammation, and autoimmunity. Develop disease... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    San Diego, CA
    24 days ago
  • Associate Principal Scientist, Medicinal ChemistryWe are seeking an accomplished medicinal chemist and project leader to drive drug discovery programs from Hit-to-Lead through Development Candidate nomination. The individual will define and execute medicinal chemistry strategy... 
    Principal
    Summer holiday
    Local area

    Neomorph

    San Diego, CA
    2 days ago
  •  ...Neomorph is seeking an experienced drug discovery biologist with extensive experience...  ...expertise and providing mentorship to junior scientists. Required Qualifications PhD...  ...managing teams of one or more associate scientists What we offer:   ~ Industry... 
    Principal
    Casual work
    Summer holiday
    Local area
    Flexible hours
    Shift work

    Neomorph, Inc.

    San Diego, CA
    more than 2 months ago
  • The Principal Scientist, Translational Medicine will play an important role in our organization,...  ...and supporting the translation of drug discovery programs into the clinic. The full-...  ...regulations.Qualifications: PhD (or MD) in immunology/rheumatology and molecular biology or... 
    Principal
    Full time

    Real Staffing Group

    San Diego, CA
    18 hours ago
  • $45 - $55 per hour

     ...against undruggable targets in the oncology and immunology space.   We are uniquely structured with opportunities for all scientists to contribute to both established programs...  ...dynamic work culture where your ideas and discoveries are valued and will have an impact.  We... 
    Hourly pay
    Temporary work
    For contractors
    Local area

    Vividion Therapeutics, Inc

    San Diego, CA
    2 days ago
  •  ...OPPORTUNITY We are seeking a highly motivated Senior Scientist to join our R&D Operations team and advance...  ...at the cutting edge of antibody engineering, immunology and immune‑oncology contributing to groundbreaking drug discovery. KEY RESPONSIBILITIES Design and Execute... 
    Principal
    Full time
    Flexible hours

    Valora Therapeutics, Inc.

    San Diego, CA
    3 days ago
  • $114k - $228k

     ...work for diversity, working mothers, female executives, and scientists. The OpportunityThis position works out of our San Diego...  ...accessible, molecular-based solutions.   Position OverviewThe Associate Principal Bioinformatics Scientist is self-driven, working on... 
    Principal
    Work at office
    Worldwide
    Shift work
    Night shift

    Abbott

    San Diego, CA
    4 days ago
  •  ...several key therapeutic areas including immunology, oncology and neuroscience - and...  ...YouTube. Job Description We seek a Principal Scientist II, Lipid Chemistry to join an experienced...  .... Collaborate with cross-functional discovery teams to translate in vitro and in... 
    Principal
    Full time
    Temporary work
    Work experience placement
    Local area

    AbbVie Inc.

    San Diego, CA
    more than 2 months ago
  • $176.2k - $277.3k

     ...Summary: We are seeking a Discovery Program Leader (DPL) to...  ...meetings focused primarily on immunology and oncology . This position...  ...and assess potential risks associated with therapeutic targets or...  ...experience as a non-clinical safety scientist (e.g. Toxicology, Pathology... 
    Principal
    Full time
    For contractors
    Local area
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    San Diego, CA
    27 days ago
  • $115k - $130k

     ...ABOUT THE ROLE We are seeking a Scientist I (Ph.D. or equivalent, with approximately...  ...test therapeutic molecules emerging from discovery biologics workstreams. You will closely...  ...in protein sciences, analytics, and immunology to support lead discovery, characterization... 
    Full time
    Relocation package
    Flexible hours

    Avalon BioVentures

    San Diego, CA
    10 hours ago
  •  ...several key therapeutic areas including immunology, oncology and neuroscience - and...  ...AbbVie is seeking a driven and innovative Associate Scientist II, in vitro Preclinical Development,...  ...mRNA-tLNP pipeline programs from early discovery through IND-enabling studies Execution... 
    Full time
    Temporary work
    Local area

    AbbVie Inc.

    San Diego, CA
    20 days ago
  • $40 - $50 per hour

     ...targets in the oncology and immunology space. We are uniquely...  ...with opportunities for all scientists to contribute to both established...  ...where your ideas and discoveries are valued and will have an...  ...seeking a highly motivated Associate Scientist, Preformulation Sciences... 
    Hourly pay
    Temporary work
    For contractors
    Local area

    Vividion Therapeutics, Inc

    San Diego, CA
    3 days ago
  • $165k - $185k

     ...undruggable targets in the oncology and immunology space. We prize scientific...  ...dynamic work culture where your ideas and discoveries are valued and will have an impact....  ...to 2025. Job Summary: The Principal Scientist, Chemical Development will successfully... 
    Principal
    Local area

    Vividion Therapeutics, Inc

    San Diego, CA
    26 days ago
  • $176.2k - $277.3k

     ...Merck seeks a Principal Scientist to lead nonclinical drug safety strategy for discovery programs across immunology, oncology, and other therapeutic areas. The role involves risk...  ...committee reviews Identify and assess risks associated with therapeutic targets using... 
    Principal

    Merck

    San Diego, CA
    21 days ago
  • $150k - $220k

     ...undruggable targets in the oncology and immunology space. We prize scientific...  ...dynamic work culture where your ideas and discoveries are valued and will have an impact. We...  ...metabolite profiling, identification and associated enzymology of select projects. This position... 
    Principal
    Local area

    Vividion Therapeutics, Inc

    San Diego, CA
    1 day ago
  • Neomorph is seeking an experienced associate scientist with a passion for drug discovery and extensive experience with BSL2/2+ practices and routine molecular and cell biology techniques. The role will be critically involved in supporting Neomorph's internal pipeline through... 
    Summer holiday
    Local area

    Neomorph

    San Diego, CA
    4 days ago
  • $151.33k - $183.37k

     ...are seeking an accomplished Principal Scientist to advance antibody...  ...initiatives within the Therapeutic Discovery Sciences Department on the...  ...engineering approaches in oncology, immunology, neuroscience, or other...  ...scientists and research associates in a team-based laboratory... 
    Principal
    Hourly pay
    Full time
    Summer work
    Live in
    Local area
    Remote work
    Flexible hours

    RayzeBio

    San Diego, CA
    2 days ago
  •  ...pharmaceutical company in San Diego is seeking a skilled NMR Scientist. You will utilize advanced analytical techniques, primarily focusing...  ...experience and a passion for driving innovations in drug discovery. This contract position offers an engaging environment at the... 
    Contract work

    Integrated Resources

    San Diego, CA
    4 days ago
  • Principal Scientist, Medicinal ChemistryWe are seeking a highly motivated and accomplished medicinal chemistry leader to drive drug discovery programs from Hit-to-Lead through Development Candidate nomination. This individual will not only independently lead medicinal chemistry... 
    Principal
    Summer holiday
    Local area

    Neomorph

    San Diego, CA
    2 days ago
  • $84k - $120k

     ...SUMMARY We are seeking a highly skilled and motivated Senior Associate Scientist to join the Chemistry team at Iambic Therapeutics...  ...researchers, and software engineers throughout all stages of discovery, from hit identification and lead optimization through candidate... 
    Full time
    Flexible hours

    Iambic Therapeutics, Inc

    San Diego, CA
    1 day ago
  •  ...The Role We are seeking an exceptionally driven, discovery-minded Senior Scientist / Principal Scientist to lead mRNA molecule design and platform innovation...  ...provide day-to-day scientific direction to research associates and junior scientists, with potential oversight of... 
    Principal

    New Co

    San Diego, CA
    10 hours ago
  •  ...medicinal chemist with a proven track record of success in drug discovery. Candidates should be motivated to work in an intensely...  ...experience and working knowledge of target protein degradation and associated modalities (molecular glues, PROTACS) Ability to integrate... 
    Principal
    Flexible hours

    Iambic Therapeutics, Inc

    San Diego, CA
    2 days ago
  • $71.25k - $187k

     ...patients are waiting. We unite caring with discovery to help make life better for people...  ...better for people around the world. The Immunology research group focuses on discovering...  ...seeking a highly motivated and dedicated scientist with knowledge and experience of... 
    Principal
    H1b
    Flexible hours

    Eli Lilly

    San Diego, CA
    4 days ago
  • $81.5k - $141.3k

     ...working mothers, female executives, and scientists. The Opportunity This...  ...the Cancer Diagnostics Division. The Associate Research Scientist II, with some guidance...  ...posted. JOB FAMILY: Research and Discovery DIVISION: ONCO Cancer Diagnostics... 
    Full time
    Work at office
    Worldwide
    Shift work
    Night shift

    Abbott

    San Diego, CA
    1 day ago
  • $60.2k - $100.4k

    **Position Summary**Pfizer is seeking a motivated Associate Scientist to join the In Vivo Pharmacology group within the Oncology Research Unit...  ...oncology studies including small molecules and ADCs within discovery and preclinical development, including efficacy,... 
    Permanent employment
    Contract work
    H1b
    Local area
    Visa sponsorship
    Work visa
    Relocation package

    Pfizer

    San Diego, CA
    5 days ago
  • $169k - $185k

     ...transplant-related complications. Founded by pioneers in the discovery of Tr1 cells, Tr1X, Inc. is focused on developing durable,...  ...need. For more information, visit Position Summary The Principal Scientist, LNP Platform & Process Development (Scientist) is an experienced... 
    Principal
    Temporary work

    Tr1X

    San Diego, CA
    a month ago
  • $52k - $57k

     ...responsibility of the individual will be to assist in protein and other discovery reagents expression and purification, analytical assays of...  ..., to recruit, hire, train and manage highly qualified scientists to perform laboratory services using our client’s quality systems... 
    Full time
    Contract work
    Worldwide

    Eurofins USA PSS Insourcing Solutions

    San Diego, CA
    27 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Associate Principal Scientist, Immunology Discovery. Be the first to apply!