Senior AI Engineer
Citizen Health
The Problem We're building an agentic AI caregiver advocate that lives in your text messages and acts on behalf of rare disease patients and their families. It doesn't just answer questions. It makes phone calls to insurance companies, automates browser sessions to find clinical trials, prepares patients for specialist appointments using their complete medical history, navigates government benefits applications, and coordinates across multiple sub-agents to get things done. It maintains persistent memory across months of interactions and gets smarter about each patient's condition, care team, and needs over time. The AI engineering challenge: build an autonomous agent that operates reliably in one of the highest-stakes domains imaginable - where a wrong answer about a medication interaction or a missed insurance deadline has real consequences for a sick child and their family. Traditional chatbot architecture doesn't cut it. We need engineers who can design agentic systems that reason, plan, use tools, and know when to escalate to a human. The Role We're hiring AI Engineers to build the intelligence behind our AI advocate. You'll design and implement the agentic LLM systems, RAG pipelines, tool-use frameworks, and evaluation infrastructure that make it effective, reliable, and safe. This is not a research role - you'll ship production systems that real patients depend on daily. You'll work closely with Product, Platform Engineering, and clinical advisors. You'll report to the CTO. What You'll Build Agentic orchestration - Design and implement the multi-agent architecture that powers our advocate's ability to reason, plan, and execute complex multi-step tasks (scheduling appointments, filing insurance appeals, researching treatment options) with appropriate guardrails and human-in-the-loop checkpoints. RAG and medical knowledge systems - Build retrieval pipelines over patient medical records, condition-specific knowledge bases, and community-sourced data from 125+ rare disease communities. Ensure the advocate's responses are grounded in the patient's actual medical history, not generic information. Tool-use and integrations - Build and maintain the frameworks that let our agent take real-world actions: browser automation, phone calls, form filling, document generation, and API integrations with healthcare systems. Each tool-use needs to be reliable, auditable, and scoped to the right permissions. Conversation intelligence - Design the systems that make the advocate's WhatsApp conversations feel natural, contextual, and proactive. This includes long-term memory, conversation state management, personalization, and knowing when to surface information the patient didn't ask for but needs. Evaluation and safety - Build evaluation frameworks for agentic outputs in a domain where "good enough" isn't good enough. Develop testing infrastructure for multi-step agent workflows, hallucination detection, medical accuracy validation, and regression testing across model updates. Prompt engineering and model optimization - Design prompt architectures that balance capability, cost, and latency. Evaluate and integrate new models as the landscape evolves. Optimize inference costs - our unit economics depend on it. Who You Are You've built LLM-powered systems that went to production and had real users - not just demos and prototypes. You understand that the hard part of agentic AI isn't getting a cool demo working, it's making it reliable at the 95th percentile. You've dealt with the unglamorous parts: evaluation frameworks, prompt regression testing, cost optimization, and edge cases that only show up at scale. You care about the craft of building AI systems, not just the hype cycle. You've formed opinions about when to use agents vs. chains vs. simple prompts, and you can articulate the tradeoffs. You're comfortable working in a startup where the stack is evolving fast and the best architecture for next quarter might not be the one you built last quarter. Must-Have Skills 4+ years of software engineering experience, with 2+ years building LLM-powered applications in production. Strong proficiency in Python and hands-on experience with agentic AI frameworks (LangChain, LangGraph, CrewAI, AutoGen, or equivalent). Experience designing and implementing RAG systems - including chunking strategies, embedding models, vector databases, retrieval evaluation, and hybrid search. Track record building AI systems that take real-world actions (tool-use, function calling, browser automation, API orchestration), not just generate text. Strong software engineering fundamentals - you write production-grade code with tests, logging, error handling, and clear abstractions. You're an engineer who uses AI, not a prompt writer who avoids code. Experience with evaluation and testing of LLM systems - you've built evals, measured hallucination rates, and designed regression suites for non-deterministic outputs. Comfort with ambiguity and fast iteration. You've worked at a startup or early-stage company and thrived. Strong written and verbal communication - you can explain agentic architecture tradeoffs to a PM and debug a prompt chain with an engineer in the same afternoon. Preferred Skills Experience with healthcare, life sciences, or other regulated domains where AI output accuracy has high stakes (HIPAA compliance, clinical data handling). Familiarity with multi-agent architectures - designing systems where multiple specialized agents collaborate, hand off tasks, and share context. Experience with WhatsApp Business API, messaging platforms, or conversational AI at scale. Background in inference cost optimization - model selection, caching, batching, routing between models of different capability/cost profiles. Familiarity with medical data formats (FHIR, HL7, CDA) or experience building systems over medical records. Experience with voice AI, telephony APIs, or browser automation frameworks (Playwright, Puppeteer). Contributions to open-source AI/LLM tooling or active engagement with the agentic AI community. Who We Are Citizen Health was founded on the belief - shaped by firsthand lived experiences navigating healthcare - that having the right advocate is the single most important factor in achieving better care and outcomes. By uniquely combining data, AI, and community, Citizen is building a personalized AI advocate powered by patients' complete medical histories and data from thousands of other patients to generate personalized insights for clinical decisions and day-to-day challenges. Starting in rare and complex conditions, patients share their data in exchange for value, enabling biopharma and researchers with seamless access to patients and regulatory-grade data, shaving years off drug development for much-needed treatments. Citizen is founded by experienced entrepreneurs with multiple successes under their belts and is funded by top-tier investors including 8VC, Transformation Capital, and Headline Ventures, among others. We are a mission-driven team excited to be building the future of consumer healthcare. Why Join Us Build an agentic AI system in production that actually helps people - not another chatbot, not a copilot for knowledge workers, but an autonomous advocate for families navigating rare diseases. Work on problems at the frontier of agentic AI: multi-step planning in high-stakes domains, tool-use over messy real-world systems, long-term memory and personalization, evaluation of non-deterministic autonomous agents. Ship to real users immediately. Our AI advocate is live and serving patients today. Your code will be in production within your first sprint. A fast-paced, high-growth setting with expanding opportunities and clear paths for career progression. A supportive culture of learning, experimentation, and innovation, where new ideas are encouraged and explored. Compensation & Benefits Competitive salary + equity Comprehensive health, dental, and vision insurance Unlimited PTO, including 12 weeks paid parental leave Flexible remote-first work environment Work-from-anywhere 30 days per year Company offsites Our Commitment to Diversity & Inclusion: Citizen Health is proud to be an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. We welcome applicants of all backgrounds, identities, and experiences. Everyone deserves an equal chance to contribute and grow here - regardless of race, gender identity, sexual orientation, religion, national origin, age, disability, or veteran status. Don't meet every qualification? No worries! We believe that passion, curiosity, and the right mindset are just as important as a checklist of skills. If you're excited about what we're building, we encourage you to apply. Citizen Health
- Build the best products in house to help scale our work Contract length: 1-3 monthsSeniorFull timeContract work
- ...We’re looking for a Senior AI engineer to build the core intelligence behind AI teammates for finance. You’ll develop systems that go beyond copilots and actually execute work, combining reasoning, context, and action inside real enterprise workflows. What you’ll do...SeniorFull time
- ...Parasail is redefining AI infrastructure by enabling seamless deployment across a distributed network of GPUs, optimizing for cost... ...mission. About the Role We’re looking for a hungry, creative engineer who thrives in a high-trust, high-velocity environment. You’ll...SeniorFull time
$200k - $350k
...infrastructure that powers high-volume, real-time business operations across multiple systems and platforms. We are seeking a Senior AI Engineer to develop, deploy, and optimize production AI systems. What You'll Do Develop and deploy machine learning and AI...SeniorRemote jobFull timeImmediate start$170k - $210k
...Tuesday and Thursday) in Palo Alto or San Francisco. We believe high-trust teams are built in person and scaled remotely. AI-native engineering. We expect every engineer to be fluent with modern AI coding tools (Claude Code, Cursor, Copilot, and similar) and to...SeniorFull timeWork at officeImmediate startRemote workShift work2 days per week$250k - $300k
...About Us At You.com, we are building the AI Search Infrastructure that powers modern AI systems. Our goal is to create the trusted... ...more reliable, transparent, and useful. Our team includes engineers, researchers, product builders, and operators who care about solving...SeniorFull timeImmediate startRemote workWork from homeFlexible hours- ...at Fieldguide. About the Role Fieldguide is building AI agents for the most complex audit and advisory workflows. We're... ...Combinator, Elad Gil, and other top-tier investors. As a Senior AI Engineer, Quality , you will own the evaluation infrastructure that ensures...SeniorRemote jobFull timeWork at officeWork from homeFlexible hours
- ...Why Blee: Blee is an AI-first marketing content compliance platform. PayPal, NerdWallet, and Brex already trust us. We're YC-backed... ...genuinely improves how teams work. The Role This is an AI Engineer role specializing in agent system design for someone who wants...SeniorFull timeWork at officeRemote workWork visaFlexible hours3 days per week
- ...organizations to safely deploy, monitor, and scale autonomous AI agents with full visibility and governance. Our platform... ...runtime dynamics. Role Overview We are looking for a Senior Applied AI Engineer to join our on-site Research & Intelligence team in San Francisco...SeniorFull time
- ...About the Role Roger is an AI platform that frees home health clinicians from paperwork so they can focus on what matters... ...continuously improve in accuracy. We are now looking for a Senior Applied AI Engineer to build the intelligence layer at the core of Roger:...SeniorFull timeRemote workWork from home
- ...About Us At FurtherAI, we’re building the next generation of AI agents for the insurance industry - a trillion-dollar market ready... ...building experience. Now, we’re looking for an exceptional AI Engineer to join our agent team and help shape both our product....SeniorFull timeWork at office
- ...their behalf. Our customers get the support of caring nurses while AI agents handle the tedious backend work — all covered by Medicare... .... WHAT WE'RE LOOKING FOR We're looking for an AI engineer to build the LLM-powered systems at the core of our product....SeniorFull time
- ...About the role Our client is a well-funded AI startup building production-grade ML infrastructure used by enterprise customers. They are looking for a Senior AI/ML Engineer to own model training pipelines, evaluation systems, and inference serving at scale. Full-time...SeniorFull time
$230k - $340k
...business is real and worth trusting: gig platforms, marketplaces, AI companies, and commerce infrastructure at scale. Trust is... ...production data pipeline, not a research demo. We're hiring a Senior AI Engineer to own a slice of this enrichment surface end-to-end. WHAT...SeniorFull timeWork at officeFlexible hours- ...Job Description - Senior AI/ML Engineer Location: Melbourne (hybrid, 3+ days a week in our Melbourne office) About Artificial Analysis Artificial Analysis is the leading independent AI benchmarking company. We support labs, engineers and enterprises to understand...SeniorFull timeWork at office3 days per week
- ...intelligent systems that sit at the intersection of AI, biology, chemistry, and large-scale engineering. Our goal is to translate complex scientific data into... ...and training those systems. The Role As a Senior AI/ML Engineer, you will lead the design, training,...SeniorFull timeRemote workFlexible hours
- ...Senior Technical Expert Serves as a senior technical expert leading high level, enterprise-wide engineering strategies for Al-enabled systems, computer hardware/software integration, and... ...solutions for the American people. As an AI technical SME provide technical...Senior
$240k - $270k
...About the Role At Sigma, we’re not just adding AI—we’re building the future of how people work with data. Our platform... ...smarter decisions—fast. That’s where you come in. As an AI/ML Engineer, you’ll join a growing team focused on building the AI foundation...SeniorFull timeWork at officeFlexible hours- ...You walk the tightrope between craft and speed without falling off either side. The role This is the first Machine Learning Engineer role at Metriport. We have access to the richest clinical datasets in the country — longitudinal medical records for hundreds of...SeniorWork at officeWork from homeRelocationFlexible hours
$149k - $240k
...Senior AI Software Engineer San Francisco, CA Who We Are HP IQ is HP's new AI innovation lab. Combining startup agility with HP's global scale, we're building intelligent technologies that redefine how the world works, creates, and collaborates. We're assembling...SeniorFull timeTemporary workLocal areaFlexible hours$160k - $200k
...Simbe is building the AI powered operating system for physical retail. Our autonomous robots and multimodal computer... ...and store team productivity. Simbe is looking for a Senior Computer Vision / Applied AI Engineer to build production AI systems that turn store imagery...SeniorFull time$229.9k - $262.4k
Senior Lead AI Engineer,(MLX, Agentic AI, Gen AI platform Services) Overview: At Capital One, we are creating responsible and reliable AI systems, changing banking for good. For years, Capital One has been an industry leader in using machine learning to create real-time...SeniorFull timePart timeLocal area- ..., General Catalyst, GV, and Accel and enjoy multi-year runway. About the Role We’re looking for a Senior Backend or Full-Stack Software Engineer (5+ years experience) who wants to build the core systems that power last-mile healthcare delivery. At Sprinter...SeniorFull timeTemporary workWork at officeMonday to FridayMonday to ThursdayFlexible hours
- ...Job Description Job Description Looking for a Senior Forward Deployed AI Engineer to lead the deployment and customization of AI-powered solutions for real-world customer environments. This role sits at the intersection of engineering, product, and customer success...SeniorImmediate start
- ...the opportunity to thrive. The Risk Tech engineering organization is committed to tangibly reducing... ...and accurately. We are seeking a Senior Software Engineer to contribute to the technical... ...and resolving pain points with AI automation solutions Deliver scalable, reliable...SeniorHourly payWork experience placement
$182k - $242k
...Description Job Description CoreWeave is The Essential Cloud for AI™. Built for pioneers by pioneers, CoreWeave delivers a platform... ...2025. Learn more at About the Role: As a Software and AI Engineer, IT Systems, you'll design and develop AI agents and first-party...SeniorPermanent employmentFull timeTemporary workCasual workWork at officeFlexible hours- Senior AI/Data Engineer - Autonomous Agentic Systems MaxIQ is building the industry's first revenue AI platform that transforms how B2B SaaS companies manage customer journeys. Join us to pioneer autonomous agentic systems that empower sales teams with predictive insights...Senior
$211k - $235k
...Networks, and causal inference to deliver real-time analytics that were previously impossible.The RoleWe're hiring a Senior Software Engineer onto our Applied AI team to build and extend the backend systems that power our platform. This is a hands-on role on a small team...SeniorWork at office$135.2k - $198.3k
...future. Levi's is accelerating the next phase of its SAP and AI transformation by embedding intelligent automation and AI... ...the core business processes that power the company. As Senior Manager of ERP AI Engineering, you will lead the deployment and scale-up of AI-enabled...SeniorFull timeWork at officeRemote work3 days per week$150k - $250k
We are seeking a Senior AI Engineer to join our cutting-edge AI Research team. You will lead the development of innovative AI solutions including machine learning models, neural networks, and deep learning algorithms that power our next-generation products. Responsibilities...SeniorRemote workHome officeFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior AI Engineer. Be the first to apply!
- machine learning ai engineer San Francisco, CA
- ai ml engineer San Francisco, CA
- ai prompt engineer San Francisco, CA
- ai engineer San Francisco, CA
- ai engineer remote San Francisco, CA
- ai developer San Francisco, CA
- senior ai engineer San Francisco, CA
- senior technical service engineer San Francisco, CA
- senior technical consultant San Francisco, CA
- senior director product management San Francisco, CA



