Clinical PK/PD Strategy Lead | Remote

Get AI-powered advice on this job and more exclusive features. This range is provided by Crossing Hurdles. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range $175.00/hr - $250.00/hr Position: PK/PD Module Expert – Translational / Clinical Pharmacology Decision-Maker Type: Hourly contract Compensation: $175–$250/hour Location: Remote Commitment: 10–40 hours/week Responsibilities Develop gold-standard First-in-Human (FIH) dose rationales and escalation strategies for representative drug programs. Translate real-world translational pharmacology decision-making into structured guidance for AI training and evaluation. Encode decision heuristics, trade-offs, and governance-level judgment into clear rubrics and decision rules. Evaluate AI-generated PK/PD and dose-selection outputs for scientific rigor, safety, and decision quality. Surface and document unwritten decision rules used by senior translational leaders when overriding model-based recommendations. Collaborate asynchronously with AI researchers to refine model reasoning around clinical pharmacology decisions. Qualifications Strong experience in translational or clinical pharmacology within major biopharma, biotech, or specialized consulting environments. Direct ownership of FIH starting dose selection, SAD/MAD design, and Phase 2 dose selection for multiple assets. Proven experience participating in governance or review boards, including IND sign-off and dose-justification defense. Deep understanding of nonclinical-to-clinical translation, including tox, PK, PD, potency, and mechanism of action. Ability to articulate real-world decision calculus balancing safety, pharmacology, and speed-to-proof. Strong written communication skills with the ability to convert expert judgment into explicit rules and rubrics. Comfortable working independently in a remote, project-based environment. Application Process Upload resume Interview (15 min) Job details Seniority level: Associate Employment type: Contract Job function: Health Care Provider Industries: Hospitals and Health Care Referrals increase your chances of interviewing at Crossing Hurdles by 2x We’re not including external job postings or location-based anecdotes beyond what’s relevant to this role. #J-18808-Ljbffr Crossing Hurdles