Site Management Associate II (Remote CRA II)

Site Management Associate II (Remote CRA II) - Homebased - Brazil or Mexico

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

We are currently seeking a Site Management Associate II to join our diverse and dynamic team. As a Site Management Associate II at ICON, you will play a vital role in supporting the management and monitoring of clinical trial sites by ensuring compliance with study protocols, regulatory requirements, and Good Clinical Practice (GCP) guidelines. You will contribute to the efficiency of clinical research operations by providing advanced support to site management teams and fostering strong relationships with site personnel.

What You Will Be Doing:

• Conducting remote and risk-based monitoring activities for clinical trials across multiple therapeutic areas.

• Supporting site qualification, initiation, monitoring, and close-out activities in collaboration with study teams.

• Ensuring protocol compliance, data integrity, and patient safety throughout the clinical trial process.

• Performing remote data review, query management, and source documentation reconciliation to maintain high-quality clinical data.

• Building strong relationships with investigators and site staff to support smooth study execution and issue resolution.

• Reviewing study metrics, identifying potential site risks, and proactively escalating concerns when appropriate.

• Contributing to the preparation and review of study documentation, including protocols, monitoring plans, and clinical study reports.

• Supporting a highly remote monitoring model with occasional travel requirements depending on business needs.

Your Profile:

• Bachelor’s degree in a scientific or healthcare-related field.

• Minimum of 2 years of clinical research monitoring experience.

• Strong understanding of clinical trial processes, regulations, and ICH-GCP guidelines.

• Previous monitoring experience in Brazil or Mexico is required; exposure to studies in the U.S. or Canada is considered a plus.

• Excellent organizational, communication, and relationship-management skills with strong attention to detail.

• Ability to work independently and collaboratively within a fast-paced global environment.

• Comfortable working in a highly remote operational model with virtual collaboration across international teams.

• Valid U.S. visa is required, as occasional international travel may be required based on study or business needs.

• Advanced English communication skills is needed.

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What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements

• A range of health insurance offerings to suit you and your family’s needs.

• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.

• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.

• Life assurance

• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site ( to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here (

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here ( to apply