Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Research Engineer

Chai Discovery, Inc

About Chai Discovery

Chai builds the design suite for molecules. We train frontier models that learn the underlying foundations of biochemical structure and interaction, so scientists can move faster and pursue targets that other methods cannot reach.

AI is reinventing life sciences the same way it reinvented software engineering, and Chai is at the forefront of this shift. Leading pharmaceutical companies like Eli Lilly, Pfizer, and Novartis are rapidly adopting our platform to power their drug discovery programs.

Our mission is to accelerate progress towards new cures and better science, and there are countless interesting problems on the road ahead.
About the role

We are seeking an AI Research Engineer to help design, train, evaluate, and optimize Chai's core models and infrastructure, working in tight loops with research scientists. Chai's models are moving beyond protein structure prediction into real-world therapeutic engineering. This is a chance to push the frontier of AI drug design, working alongside a craft-obsessed team of micro-pessimists and macro-optimists.
  • Develop and optimize all the infrastructure & tooling upon which our AI research depends.
  • Collaborate with AI researchers to understand, implement and optimize new research directions.
  • Integrate AI models into production systems, ensuring scalability and reliability.
About you

Ideal backgrounds include high-performance computing, custom CUDA kernels and GPU programming, AI/ML + data systems at scale.
  • Bachelor's or Master's degree in Computer Science, Software Engineering, or a related field.
  • Strong proficiency in programming languages such as Python and deep learning frameworks like PyTorch.
  • Deep understanding of operating system internals.
  • Experience with HPC infrastructure such as Slurm and Kubernetes.
  • Experience with performance engineering and profiling for CPU and CPU workloads.
  • Experience writing, building, and maintaining large-scale ETL pipelines.
We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We compensate our team accordingly.
Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Research Engineer in San Francisco, CA vacancy
  • $110.7k - $379.2k

    Position Summary Research Engineer — Post-Training & Small Language Models (SLMs), Healthcare AI Three hundred fifty million Americans rely on a healthcare system whose decision-making has become slow, costly, and adversarial — care delayed by prior authorization... 
    Suggested
    Local area
    Visa sponsorship

    Deloitte

    San Francisco, CA
    2 days ago
  • $197.3k - $313.7k

     ...TeamSalesforce AI is looking for talented software and platform engineers to embed in our AI team to bridge the gap between frontier AI...  ...where your engineering skills directly enable world-class research and products used by millions?At Salesforce, we are driving the... 
    Suggested
    Full time

    Salesforce

    San Francisco, CA
    2 days ago
  • $164.6k - $313.3k

     ...s Sound Design AI group (SODA) is looking for a driven Data/ML engineer to push the boundaries of audio GenAI. Join the team behind Firefly...  ...in Adobe products.We’re a small, collaborative and efficient research team looking for highly motivated candidates of all levels with... 
    Suggested
    Full time
    Temporary work
    Local area
    Worldwide

    Adobe Systems

    San Francisco, CA
    1 day ago
  • Factory is seeking innovative Research Engineers to design and integrate advanced AI and ML capabilities that revolutionize productivity and accelerate innovation within software organizations.What you will do and achieve:Design, develop, and deploy AI-driven agentic systems... 
    Suggested
    Work at office

    The San Francisco AI Factory

    San Francisco, CA
    3 days ago
  • $200k - $225k

    About AlembicAlembic is where top engineers are solving marketing's hardest problem: proving what actually works. If you're looking for...  ...teams and customers to leverage advanced analyticsDocument research and implementation decisions for reproducibility and knowledge... 
    Suggested

    Alembic

    San Francisco, CA
    3 days ago
  • $250k - $350k

     ...Based in San Francisco, California, Turing is the world’s leading research accelerator for frontier AI labs and a trusted partner for...  ...environment types are listed here: # Environments for Software Engineering / coding agents # UI-Environments for Computer-Use/Browser... 
    Full time
    For contractors

    Turing

    San Francisco, CA
    2 days ago
  • $250k - $400k

     ...Based in San Francisco, California, Turing is the world’s leading research accelerator for frontier AI labs and a trusted partner for...  ...environment types are listed here: # Environments for Software Engineering / coding agents # UI-Environments for Computer-Use/Browser... 
    Full time

    Turing

    San Francisco, CA
    2 days ago
  • $295k

     ...training, evaluations, harnessing, and deployment—and connect that research to the patients, clinicians, and real-world outcomes we aim to...  ...population-level decisions. Work closely with researchers, engineers, clinicians, and product teams to bring health capabilities... 
    Full time
    Work at office
    Relocation package

    OpenAI

    San Francisco, CA
    6 days ago
  • $210k - $275k

     ...Research Engineer You'll build the evaluation systems that tell us whether Firecrawl actually works. That sounds simple. It isn't. Our core promise, convert any URL into clean, structured, LLM-ready data reliably, is hard to measure rigorously across millions of different... 
    Full time
    Temporary work
    For contractors
    Remote work
    Visa sponsorship
    Flexible hours

    firecrawl

    San Francisco, CA
    10 hours ago
  • $200k - $350k

     ...agents, diffusion model training), second-time technical founders, engineers that made 100+ games for Voodoo, Supersonic, Sidemen and built...  ...monetize highly engaging games & 3D environments. Our current research spans: Distributed multi-agent orchestration systems for... 
    Visa sponsorship
    Relocation package

    ROAM

    San Francisco, CA
    3 days ago
  • $225k

     ...believe the most promising path to safe AGI lies in automating research and code generation to improve models and solve alignment more...  ...compute to achieve this goal. About the role As a Research Engineer, you'll work on training, evaluating, and serving large AI... 
    Relocation
    Visa sponsorship

    Magic AI Corp.

    San Francisco, CA
    1 day ago
  •  ...Research Engineer On Physical Ai Team Hedra is a pioneering generative modeling company — first models to market — now building a Physical AI team to bring these models to real-world industry and economy use cases. As a Research Engineer on our Physical AI team, you... 
    Work at office

    HEDRA INC

    San Francisco, CA
    2 days ago
  • $140k - $250k

     ...This is the company's top hiring priority and a genuinely hard research problem. Because data flows through a decentralized marketplace...  ...scale is the single biggest bottleneck to growth. As a Research Engineer, you will build the automated systems that verify and assure... 
    Full time
    Work at office
    Remote work

    talentpluto

    San Francisco, CA
    1 day ago
  • $9.7k - $19k

     ...Introduction The Center for AI Safety (CAIS) is a leading research and field-building organization on a mission to reduce societal...  ...technical, societal and policy solutions. As a research engineer intern here, you will work very closely with our researchers on... 
    Full time
    Internship
    Local area

    Center for Ai Safety

    San Francisco, CA
    3 days ago
  • $120k - $200k

     ...We are actively seeking a Research Engineer specializing in Machine Learning and AI to play a pivotal role in pioneering advanced solutions. In this role, you will lead end-to-end research projects and contribute technical expertise to build scalable systems, all within... 
    Casual work
    Work at office

    Erth.AI Inc.

    San Francisco, CA
    3 days ago
  •  ...business communication means permissions, redaction, and security are things we have to think about as well. If you want to have your research come into contact with reality, Ando is the place for it. Some concrete research problems on our plate right now:... 
    Work from home

    Ando

    San Francisco, CA
    10 hours ago
  • $225k - $400k

     ...Research Engineer Title of Role: Research Engineer Location: San Francisco, onsite Company Stage of Funding: Venture-Backed — Software Development, AI, Devtools, Data, Enterprise, B2B Office Type: Onsite Salary: $225K–$400K Company Description We're... 
    Work at office

    Recruiting from Scratch

    San Francisco, CA
    2 days ago
  •  ...About us We're reverse-engineering the origin of life - one of the great unsolved problems in science, and one we think AI finally...  ...scientists, and bench scientists. We hold ourselves to the rigor of a research institute, but we ship like an engineering firm. Global team,... 
    Visa sponsorship
    Shift work

    Dayhoff Labs

    San Francisco, CA
    11 hours ago
  •  ...and the verifiers (how we can keep evaluating Aidan's performance in real scenarios). Making that feel human is one of the hardest engineering problems in AI, and our engineering team's unique ability to solve it is what makes Sable special. What you'll do Improve... 

    Sable AI, Inc

    San Francisco, CA
    4 days ago
  • $227.2k - $284k

     ...tooling that power agentic AI in production, paired with applied ML research, design, and evaluation to ensure these systems perform...  ...looks like.About the RoleAs a Staff Machine Learning Research Engineer, you will operate across the full breadth of AIS’s technical needs... 
    Full time

    Scale AI

    San Francisco, CA
    3 days ago
  • $174k - $252k

    Research new alignment methods, studying alignment failures, and applying AGI-scalable alignment techniques to frontier models.Develop...  ...:Bachelor's degree in Computer Science, a related Software Engineering field, or equivalent practical experience.3 years of experience... 

    Google

    San Francisco, CA
    5 days ago
  • $350k

     ...want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role: You want to... 
    Work at office
    Visa sponsorship
    Flexible hours

    Anthropic

    San Francisco, CA
    2 days ago
  •  ...workflows. Evaluate prototypes and collaborate with the team to integrate successful approaches into production systems. Track research in LLMs, information retrieval, and developer tooling. Requirements B.S. in Computer Science or equivalent. Research... 
    Full time
    Work at office
    Relocation package

    Greptile

    San Francisco, CA
    4 days ago
  •  ...data usability, quality, and impact on key benchmarks and guide data generation, augmentation, and curation. Collaborate with AI researchers, applied AI teams, and data producers to align evaluations with training objectives. Own benchmarking, evaluation, and failure... 
    Full time
    Work at office
    Relocation package

    Mercor

    San Francisco, CA
    8 days ago
  • $320k

     ...Artificial Intelligence) is building the computational platform that powers Lila's work in the life sciences. We are looking for a Research Engineer to own and build the core codebase that our models plug into, the foundation on which our scientists build and ship their work... 
    Full time
    Work at office
    Local area
    Flexible hours
    Shift work

    Lilasciences

    San Francisco, CA
    5 days ago
  • Senior Experimental Research Engineer, Electromagnetics Senior Experimental Research Engineer, Electromagnetics 3 days ago Be among the first 25 applicants Gridware is a San Francisco-based technology company dedicated to protecting and enhancing the electrical grid. We... 
    Full time

    Gridware

    San Francisco, CA
    4 days ago
  •  ...At Resolve, we’re building Agentic AI that empowers software engineers by automating production engineering and SRE workflows. Our models...  ...You’ll Do Develop AI‑powered workflows end‑to‑end, balancing research and engineering to create production‑ready AI models Build... 
    Full time
    Work at office
    Visa sponsorship
    Flexible hours

    Resolve AI

    San Francisco, CA
    4 days ago
  • Applied Research Engineer - San Francisco As an applied research engineer at Confidential, you’ll build high performance building blocks and large scale pipelines to understand video with high precision at internet scale. Often this involves working on ambiguous research... 

    My HR Solutions

    San Francisco, CA
    17 hours ago
  • $160k - $250k

    Join to apply for the Founding Research Engineer role at Adam Join to apply for the Founding Research Engineer role at Adam This range is provided by Adam. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range... 
    Full time

    Adam

    San Francisco, CA
    4 days ago
  • A leading AI technology firm in San Francisco is looking for a Research Engineer, Post-Training. This role involves optimizing AI models and developing algorithms to enhance data efficiency. Candidates should have a PhD or equivalent and experience with machine learning... 

    Character.AI

    San Francisco, CA
    4 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Research Engineer. Be the first to apply!