Responsible AI Manager - Agentic AI Governance

Career Category Information Systems Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Responsible AI Manager - Agentic AI Governance What you will do Let’s do this. Let’s change the world. The Responsible AI Manager, Agentic AI sits within the Amgen Responsible AI team in the Artificial Intelligence & Data Science organization. You will play a key role in shaping and operationalizing practical, risk‑based governance for agentic AI across Amgen, helping ensure these technologies can be used broadly, responsibly, and with appropriate controls. By enabling innovation at scale while protecting trust, quality, safety, and compliance, this work helps Amgen advance AI responsibly in support of its mission. You will enable governance‑by‑design for enterprise AI capabilities, while also defining governance approaches for other agentic AI adoption patterns, including third‑party solutions and embedded or configurable agentic AI capabilities in existing or new software and platforms. This position sits at the intersection of Responsible AI governance, risk and compliance, cybersecurity, law, data science, and enterprise AI platform enablement. You will work closely with teams that own and operate enterprise AI platforms, tools, and capabilities, to translate Responsible AI, compliance and regulatory expectations into actionable governance requirements. Responsibilities: Lead the design, implementation, and continuous improvement of governance approaches for agentic AI, partnering with AI platform and product owners, data science teams, cybersecurity, legal, compliance, privacy, and quality functions. Translate Responsible AI expectations, organisational policies, and regulatory requirements into actionable governance requirements, operational processes, and user guidance. Define governance requirements for technical controls and safeguards, such as usage restrictions, access controls, human oversight, logging, anomaly detection, incident escalation, and mechanisms to pause, restrict, or disable AI‑enabled functionality when appropriate. Monitor emerging AI technologies, risks, standards, and regulatory developments; assess their impact on the enterprise, and evolve governance frameworks, standards, and controls to enable responsible adoption of new AI capabilities. Develop and maintain Responsible AI policies, standards, playbooks, procedures, guidance, and other control documentation to support consistent AI governance, regulatory compliance, and audit readiness. Develop materials for leadership, governance forums, and cross‑functional working groups, communicating risks, recommendations, decisions, implementation progress, and governance outcomes to support informed decision‑making. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications. Basic Qualifications: Doctorate degree OR Master’s degree and 2 years of experience in AI/ML product development, MLOps/LLMOps, data science, software engineering, Responsible AI, AI governance, AI risk, or a related field Bachelor’s degree and 4 years in AI/ML product development, MLOps/LLMOps, data science, software engineering, Responsible AI, AI governance, AI risk, or a related field Associate’s degree and 8 years in AI/ML product development, MLOps/LLMOps, data science, software engineering, Responsible AI, AI governance, AI risk, or a related field High school diploma / GED and 10 years in AI/ML product development, MLOps/LLMOps, data science, software engineering, Responsible AI, AI governance, AI risk, or a related field Preferred Qualifications: Must-Have Skills: Technical fluency in AI/ML, generative AI, or agentic AI systems, including the ability to engage with technical teams on topics such as model and agent behavior, logging and telemetry, tool use, system prompts or instructions, configuration files, SDKs, APIs, and access controls. Strong understanding of AI risks and governance considerations, including human oversight, accountability and transparency, privacy, validity and reliability, appropriate use, and fairness and bias mitigation. Familiarity with AI regulatory, policy, or standards developments, such as the EU AI Act and NIST AI Risk Management Framework. Ability to work effectively across technical, legal, compliance, risk, cybersecurity, data science, and business teams, including influencing stakeholders without direct ownership of the underlying technology platforms. Nice-to-Have: Prior hands‑on experience in data science, machine learning, software development, AI product development, MLOps, LLMOps, platform governance, or technical AI risk management. Experience with agentic AI, generative AI platforms, AI assistants, custom AI tools, workflow automation, AI‑enabled software features, runtime monitoring, or enterprise AI product governance. Experience translating Responsible AI, AI governance, risk, compliance, or regulatory expectations into practical business processes, governance requirements, technical control expectations, guidance, or operating models. Prior work in a regulated industry, such as biotechnology, pharmaceuticals, healthcare, financial services, or another environment with significant compliance, privacy, security, quality, or regulatory expectations. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan Stock‑based long‑term incentives Award‑winning time‑off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Salary Range 126,510.60USD -171,161.40 USD Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit and follow us on #J-18808-Ljbffr Amgen Inc. (IR)