Principal Scientist, Cancer Vaccines

ICR's Cancer Prevention science centers on developing preventive cancer vaccines. We are hiring a Principal Scientist with a deep background in peptide-based vaccine development, cancer immunology and immuno-oncology. As part of our mission to prevent age-related disease, training human immune systems to spot and destroy cancer before it becomes a problem is critical. We truly believe that an ounce of prevention is worth a pound of cure.

With us, you'll get to:

• Lead ICR's Cancer Prevention Group in researching and developing novel preventive cancer vaccines
• Drive end-to-end design, execution and interpretation of preclinical vaccine studies, directly shaping the path to human translation
• Collaborate closely external KOLs and CRO partners to turn cutting-edge cancer immunology insights into first-in-class preventive vaccine programs

Please apply if you have:

• A PhD, MD or both and at least 10 years of vaccine development experience, preferably cancer vaccines
• In-depth knowledge of and experience researching personalized cancer vaccines, including peptide-based vaccines and neoantigen-based cancer vaccines
• Extensive experience with vaccine epitope identification, selection/prioritization (of neoantigens), vaccine adjuvants and immune response monitoring
• Experience with molecular T cell receptor repertoire analysis and tracking, T cell proliferation assays, cytokine release assays and ELISPOT
• Experience deriving antigen-specific T cell clones and lines
• Expertise in cancer stem cell antigens, tumor-associated antigens, neoantigens, immuno-editing and immuno-monitoring
• Extensive knowledge of and experience with vaccine delivery systems, including peptide-, cell- and viral-based systems
• The ability to work well with CROs and manage external projects
• Even if you don't meet all of these criteria, please apply anyway

And you'll need:

• An easygoing, friendly personality
• The ability to work in the United States without sponsorship

If you don't combine your cover letter with your CV or resume when you apply through LinkedIn, after you apply please send your cover letter only to: View email address on click.appcast.io with "Cover [Your name]" as the Subject line.

Position title and salary are commensurate with experience.

The compensation ranges listed below are starting ranges.

Starting base pay range: $165,000/yr - $215,000/yr

Starting bonus range: $7,500/yr - $20,000/yr