Process Chemist
$70 per hourDiscover International
Process Chemist – Peptide / API Manufacturing
LA County California (On-Site)
$70/hour
6-Month Contract-to-Permanent Opportunity
A leading peptide manufacturing organization is seeking a Process Development Scientist to support the advancement of innovative API processes from early development through full-scale cGMP manufacturing. This is a hands-on opportunity to work at the intersection of chemistry, process development, and commercial manufacturing supporting next-generation peptide and oligonucleotide medicines .
The ideal candidate will bring strong synthetic chemistry expertise, process optimization experience, and the ability to collaborate cross-functionally in a fast-paced GMP manufacturing environment.
Key Responsibilities
- Develop, optimize, and scale synthetic processes for peptide and oligonucleotide APIs from lab through manufacturing
- Support technology transfer activities from Process Development into Production across internal sites
- Monitor and optimize chemical reactions, purification operations, isolation, and drying processes
- Perform and interpret analytical testing including High-performance liquid chromatography purification, in-process sampling, and related process analytics
- Troubleshoot process, equipment, and manufacturing challenges to improve efficiency and yield
- Partner closely with Production, QA, QC, Engineering, and Supply Chain teams to ensure compliant execution
- Author and review batch records, protocols, reports, SOPs, and technical documentation
- Drive continuous improvement initiatives focused on safety, right-first-time execution, and scalable manufacturing readiness
Qualifications
- PhD in Chemistry, Chemical Engineering, Organic Chemistry, or related discipline with 1+ year industry experience
- OR
- Master’s degree with 5+ years relevant industry experience
- Minimum 4+ years of industry experience in organic chemistry, process chemistry, or API development
- Experience with peptide chemistry, peptide manufacturing, or complex molecule synthesis strongly preferred
- Strong understanding of synthetic route development, scale-up, and process optimization
- Familiarity with cGMP environments , deviation management, and technical documentation
- Hands-on experience with analytical techniques such as High-performance liquid chromatography, UPLC, and reaction monitoring tools preferred
- Excellent troubleshooting, communication, and independent problem-solving skills
Preferred Experience
- Solid Phase Peptide Synthesis (SPPS)
- Oligonucleotide API manufacturing
- Tech transfer between R&D and commercial manufacturing
- Purification, filtration, lyophilization, and drying operations
- Working in multi-site manufacturing environments
Why Join
- Contract-to-hire opportunity with long-term growth potential
- Work with a recognized leader in peptide manufacturing
- Direct impact on therapies advancing modern medicine
- Strong exposure to development through commercial-scale production
Vacancy posted 22 hours ago
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