Clinical Lab Associate 1 (3rd Shift, Fri - Tues)

Company Overview At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California. Shift Availability Friday - Tuesday: 10pm - 6:30am (3rd Shift) Training hours may be different from your shift schedule. Responsibilities Perform nucleic acid extraction from various sample types in a Biosafety Level 2 laboratory (e.g., FFPE, blood, plasma, and more) Quantify extracted materials by following QC protocols Prepare extracted materials for library prep using automated and manual procedures. Record sample processing workflows in real-time through a Laboratory Information Management System (LIMS) Maintain robotic liquid handlers and other instruments for optimal performance Assist in data transfer and basic QC evaluation of data Perform troubleshooting and system evaluations when necessary, in communication with the automation support team, laboratory supervisor, and/or third‑party technical support teams Escalate issues to a supervisor when problems arise with sample processing Maintain appropriate supplies and equipment to maximize department efficiency and meet established budgetary and quality goals Support and ensure compliance with the laboratory’s quality control procedures and policies Document all corrective actions taken when test systems deviate from the laboratory’s established performance specifications Demonstrate knowledge of laboratory safety protocols Demonstrate commitment to quality and continuous improvement Use effective two‑way communication and participate in general laboratory meetings Perform other duties as assigned, including performing workflows outside of extractions Requirements BA/BS in a biological discipline 0-2 years of relevant laboratory experience Familiarity with Hamilton, or other robotic liquid handlers, is desired Familiarity with LIMS or sample management tracking systems is desired Familiarity with quality control of samples and quantification devices (e.g., TapeStation, Qubit, qPCR) Flexible and adaptive in a frequently changing environment Strong communication skills, ensuring effective communication when issues arise. Strong organizational skills and attention to detail Ability to analyze and solve basic problems Ability to work as part of a team in a highly collaborative environment Ability to work independently with minimal supervision Desire to learn new skills and grow his/her knowledge of next‑generation sequencing technologies Strong desire to work in a demanding, high‑energy, hands‑on environment Compensation The hiring range for this position is $27.50 to $34.60 per hour, which may factor in various geographic regions. This shift is eligible for an additional shift premium. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job‑related knowledge, skills, and experience among other factors. Our full‑time regular positions also include an annual performance‑based bonus (or a sales incentive plan) and long‑term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered. Equal Opportunity Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you. Benefits Our full‑time regular positions also include an annual performance‑based bonus (or a sales incentive plan) and long‑term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits / EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.) #J-18808-Ljbffr Personalisinc