Sr. Software Engineer (Operational Systems Team)
$153k - $179kCleerly
Job Description
Job Description
About Cleerly
We're Cleerly – a healthcare company that's revolutionizing how heart disease is diagnosed, treated, and tracked. We were founded in 2017 by one of the world's leading cardiologists and are a growing team of world-class engineering, operations, medical affairs, marketing, and sales leaders. We raised $223M in Series C funding in 2022 which has enabled rapid growth and continued support of our mission. In December 2024 we received an additional $106M in a Series C extension funding. Most of our teams work remotely and have access to our offices in Denver, Colorado, New, York, New York, Dallas, Texas, and Lisbon, Portugal with some roles requiring you to be on-site in a location.
Cleerly has created a new standard of care for heart disease through value-based, AI-driven precision diagnostic solutions with the goal of helping prevent heart attacks. Our technology goes beyond traditional measures of heart disease by enabling comprehensive quantification and characterization of atherosclerosis, or plaque buildup, in each of the heart arteries. Cleerly's solutions are supported by more than a decade of performing some of the world's largest clinical trials to identify important findings beyond symptoms that increase a person's risk of heart attacks.
At Cleerly, we collaborate digitally and use a wide variety of systems. Our people use Google Workspace (GMail, Drive, Docs, Sheets, Slides), Slack, Confluence/Jira, and Zoom Video, prior experience in these areas is a plus. Role or department specific technology needs may vary and will be listed as requirements in the job description.
While we are mostly a remote company, travel is required for some team meetings and cross function projects typically once per month or once per quarter, for some roles like sales or external facing roles travel could be up to 90% of the time.
Cleerly is committed to providing safe and effective medical software that meets customer needs and our intended use. The adherence to all applicable regulatory and statutory requirements establishes a clear framework for setting measurable quality objectives. Our commitment to continually improving our products and processes proactively manages risks, ensuring ongoing compliance throughout the entire software lifecycle. Understanding this role's relevance and importance is critical to achieving Cleerly's quality objectives.
About the Team
The Operational System team owns the Core Lab Case Management platform, which is the central nervous system of our laboratory operations. We build the workflows that orchestrate the lifecycle of each case, ensuring that complex case data moves seamlessly through the lab and is categorized and prioritized correctly. By optimizing how cases are processed, we ensure our operations remain scalable and our COGS grows efficiently, not linearly, alongside our business.
About the Opportunity
We're seeking a Senior Software Engineer to drive key technical initiatives across our platform. In this high-impact role, you'll own complex systems end-to-end, influence architecture decisions, and mentor other engineers, playing a pivotal part in shaping our engineering culture and scaling enterprise capabilities.
Responsibilities
- Develop scalable backend services (Node.js, TypeScript) and performant user-facing applications (React, Next.js).
- Design extensible system architectures and make pragmatic trade-offs that balance performance, security, and maintainability.
- Own full lifecycle delivery of complex features, from architectural planning and API design to UI implementation and post-release observability.
- Ensure high availability and observability of our services; improve alerting, logging, and incident response across the stack.
- Set and uphold strong engineering standards via code reviews, technical mentorship, and design documentation.
- Partner with product, design, and stakeholders to align engineering with business goals and user needs.
- Lead technical design reviews and system decomposition efforts across teams.
- Proactively identify risks and gaps in operational or architectural resilience, and drive durable improvements.
- Collaborate closely across engineering to reduce knowledge silos and ensure continuity in critical systems through cross-training and documentation.
- Participate in on-call rotations and lead post-incident reviews, driving long-term reliability improvements across systems.
Requirements
- Bachelor's or Master's degree in Computer Science, Software Engineering, or related field (or equivalent experience).
- 8–12 years of software engineering experience, with deep expertise in backend systems (Node.js, PostgreSQL) and experience with modern front-end frameworks (React, TypeScript).
- Proven track record of architecting and delivering scalable systems in production environments.
- Experience mentoring engineers and raising the technical bar through reviews and design feedback.
- Strong systems thinking with the ability to evaluate tradeoffs in scalability, reliability, and maintainability.
- Experience designing for observability and operational excellence (e.g., logs, alerts, dashboards, runbooks).
- Comfortable operating in ambiguity and driving clarity across product, engineering, and business stakeholders.
Preferred:
- Familiarity with regulated domains (e.g., healthcare, fintech) and high-availability infrastructure.
- Experience with containerized cloud environments (Docker, AWS ECS/EKS), CI/CD automation, and infrastructure as code.
- Exposure to event-driven architecture or microservices with asynchronous workflows.
If you're excited to solve meaningful problems at scale, influence architecture across systems, and mentor the next generation of engineers, we'd love to hear from you.
The base salary range for this role varies by location and is aligned to market benchmarks.
- Candidates located in higher-cost labor markets , including California, Washington, New York, New Jersey, Connecticut, Massachusetts, and Washington, DC represent the middle to high end of the range, while candidates located in all other U.S. locations represent the low to middle end of the range.
- Final compensation is determined based on location, experience, skills, and internal equity.
This role is eligible for a 15% target annual bonus , resulting in the following base salary and Total Target Compensation (TTC) ranges:
- Base Salary: $153,000 - $179,000
- TTC: $176,000 - $206,000
*Total Target Compensation (TTC): Total Cash Compensation (including base pay, variable pay, commission, bonuses, etc.) Additionally, stock options, paid benefits, and employee perks are part of your total rewards.
Working at Cleerly takes HEART. Discover our Core Values:
- H: Humility - be a servant leader
- E: Excellence - deliver world-changing results
- A: Accountability - do what you say; expect the same from others
- R: Remarkable - inspire & innovate with impact
- T: Teamwork - together we win
Don't meet 100 percent of the qualifications? Apply anyway and help us diversify our candidate pool and workforce. We value experience, whether gained formally or informally on the job or through other experiences. Job duties, activities and responsibilities are subject to change by our company.
OUR COMPANY IS AN EQUAL OPPORTUNITY EMPLOYER. We do not discriminate on the basis of race, color, national origin, ancestry, citizenship status, protected veteran status, religion, physical or mental disability, marital status, sex, sexual orientation, gender identity or expression, age, or any other basis protected by law, ordinance, or regulation.
For more information see our Privacy Policy (-policy). All official emails will come from @cleerlyhealth.com email accounts.
#Cleerly
$153k - $179k
...leading cardiologists and are a growing team of world-class engineering, operations, medical affairs, marketing, and... ...and use a wide variety of systems. Our people use Google Workspace (... ...providing safe and effective medical software that meets customer needs and our...SeniorRemote work- ...intelligence, helping decision makers and operators navigate what’s happening now and... ...below.Position SummaryThe Senior Staff Software Systems Engineer - Cybersecurity & Compliance serves as... ...cybersecurity, program, and operational teams, this engineer interprets security...SeniorFull time
$115k - $140k
...of out-of-the-box communication systems for satellites, UAVs, launch... ...thinking individuals to join our team. We are looking to add a Senior Flight Software Engineer I to our Internal Missions team... ...from Linux-based satellite operating systems to low-level embedded products...SeniorPermanent employmentFull timeContract workWork experience placementLocal area- ...intelligence, helping decision makers and operators navigate what’s happening now and... ...the job details below.The Senior Staff Software Systems Engineer serves as a senior technical authority... ...execution across multiple engineering teams.Success in this role requires strong systems...SeniorPermanent employmentFull time
$111.61k - $131.3k
...technology. As part of our team, you can explore what... ...business, product, operations, and technology... ...and internal/external systems using REST/SOAP APIs,... ...product, operations, and engineering teams to deliver high-... ...Experience8+ years of software engineering experience...SeniorFull timeLocal area3 days per week- ...looking to build tools that engineers actually keep in their workflow... ...most of your time on agentic systems: the tool surfaces our agents... ...goes to customers. The team is small. Your work will be visible... ...and shipping production SaaS software ~ Deep in at least one...SeniorLive inImmediate startRemote workHome officeWeekend work
$120k - $150k
...is seeking an experienced and technically deep Sr. Microsoft Azure Engineer to join the Microsoft Operations team in San Diego. This is a senior individual contributor... ...Science, Information Technology, Information Systems, or a directly related field; OR equivalent...SeniorFull timeWork at officeLocal area$140k - $177k
...developing the Symphony supersonic engine, which powers the Overture... ...plans into a single, coherent system that accelerates everything we... ..., and speed for the entire team. Collaborate directly with aerospace... ...workflow needs into working software. Iterate quickly with...SeniorPermanent employmentFlexible hours- ...Job Description We are seeking an experienced, Sr. Software Engineer / Architect to join our Satellite Systems team. In this integration-focused role, the... ...collaboration with customers and vendors. Ensure the operation and maintenance of mission-critical software...SeniorFor subcontractorImmediate start
$140k - $177k
...Englewood, Colorado, is seeking a developer to integrate core systems into a unified workflow and build full-stack internal applications... ...0 annually, and opportunities for collaboration with aerospace engineers to enhance workflows. Come join the mission to revolutionize...Senior$110k - $155k
...with the core digital systems, specialized AI, and data... ..., and back-office operations. Underpinned by unmatched... ...Site Reliability Engineer to own the reliability... ...responsibility, requiring strong software engineering skills and... ..., and operations teams. ~ Operate with...SeniorContract workWork at officeWork from homeFlexible hours$170.6k - $261.3k
...the Role The Smart Collect team builds the platform that... ...cloud. We are seeking a Senior Software Engineer to develop the services,... ...traceability, privacy, and operational excellence. You will collaborate... ...including ownership of production systems. ~ Bachelor’s degree in...SeniorFull timeLocal areaRemote workWork from homeRelocation packageFlexible hours$86.25k - $158.13k
...the company’s success. As a Software Engineer Sr within PNC's Technology organization... ...business and technology teams to deliver scalable, secure,... ..., QA, security, and operations teams to deliver reliable enterprise... ...with version control systems such as Git and collaborative...SeniorFull timeTemporary workPart timeWork experience placementWork at office$145k - $192.5k
...Global Information Security (GIS) team is seeking a Cyber Threat Defense Sr AI/ML Engineer to build and integrate advanced... ...models (LLMs), and agentic AI systems. This is a senior individual contributor... ..., the available data, and the operational risk profile.Build LLM-based...SeniorFull timeWork at officeShift workDay shift- ...DESCRIPTION Position Title: SCADA Engineer Reports To: Manager –... ...power platform that owns and operates over 7 GW of utility-scale... ...with engineering and operations teams to deliver reliability in all aspects of control and data systems. Provides support for various...Full timeWork at officeRemote work
- ...variable cost.Job Description This is a research and development team· Skillso Help to stand up distributed systemso Scala, Spark,... ...languageso Understanding how to develop in multi-core distributed system environment o TCP/IP- networking understanding, clusters, distributed...SeniorImmediate start
- Description Senior Software Engineer Why YOU want this position At Enverus... ...automating crucial business operations. Of course, this wouldn’t be... ...is why we have built a team of individuals from a diverse... ...Engineers on this team own systems end-to-end, including architecture...SeniorTemporary work
$50 per hour
...Space is seeking a full time Software Engineer. In this role, you will... ...and information gathered from system users to develop software. Corrects... ...program errors, prepares operating instructions, compiles... ...languages such as C, C++- Standard teaming: Ability to work with multi-...SeniorFull timeTemporary workWork experience placementCasual workFlexible hours- SciTec seeks a Sr Staff/Senior Software Engineer to support Missile Defense Solution software in an operational setting. You will work onsite at Buckley Space Force Base, Aurora,... ...performance, and reliability of critical mission systems. Ideal candidates have 6+ years in...Senior
$135k - $175k
...outside of work.Job Title:Sr. Software EngineerReporting To:... ...and manufactures systems to survive the harsh environments... .... Our Space Vehicles team is growing and is... ...for a Sr. Software Engineer to support the development... ...out of Arvada, CO and operates on a 9/80 hybrid work...SeniorFull timeWork at officeRelocation packageFlexible hours- ...your future as we are, join our team.KPMG is currently seeking a Sr. Software Engineer to join our Tax Ignition Team. This... ...principles, code reviews, and system designAct with integrity,... ...trustworthiness, and safeguard business operations and company reputation. Pursuant...SeniorLocal area
$135.2k - $306.4k
...Job Description Senior / Principal Software Engineer or Architect Database Engine, Search & Document Systems We are looking for senior systems builders to... ...fixes, working with migration and Developer Operations teams, and occasionally engaging directly with customers...SeniorTemporary workFlexible hours$170.69k - $250k
Position: Sr Principal Spacecraft Systems Engineer / Mission Architect (Systems Engineer, Sr. Principal... ...for future generations.Join our team of innovators and get a chance to... ...sensing, approach profiles, autonomous operations envelopes, and relative navigation...SeniorPermanent employmentLocal area$168.1k - $227.4k
...deadline: Aug 18, 2026The Platform Engineering and Emerging Technologies (PEET) team is hiring for a Senior Software Development Engineer to lead development and manage operations for AWS Managed Grafana,... ...and most complex distributed systems in the world, and we need...SeniorInternshipFlexible hoursNight shiftWeekend work$94k - $115k
...Investment Reporting Technology team partners closely with Finance, Accounting, Investment Operations, and other Technology teams... ...functions.The Senior Software Engineer will serve as a hands-on Murex... ...investment reporting and derivatives systems.Job Description...SeniorFull timeContract workWork at officeRemote workWorldwideWork visaRelocation package3 days per week- ...com in Colorado seeks an experienced embedded software architect to design, implement, test, and debug real-time systems that integrate firmware and hardware. You will... ...software integration, and device drivers. Senior engineers collaborate across disciplines to guarantee...Senior
- ...Sr. ServiceNow Software Engineer This Sr. ServiceNow Software Engineer will know ServiceNow well enough to confidently develop within the platform... ...resource to not only develop, but also coach their dedicated team as needed. They need someone who can help Centura make...Senior
$129k - $152k
...leading cardiologists and are a growing team of world-class engineering, operations, medical affairs, marketing, and... ...and use a wide variety of systems. Our people use Google Workspace (... ...providing safe and effective medical software that meets customer needs and our...Remote work- ...Coordinating with the other IT teams to collect design... ...papers based on the operative needs # Assisting... ...Analyze the needs of large systems and breaking them down... ...requirements to software designers and developers... ...IT experience in Data Engineering, Data Quality, Data Migrations...Senior
- ...Sr. Staff Embedded Software Engineer Location: Littleton, CO or Jacksonville, FL Overview Seeking a... ...reliable firmware for microprocessor-based systems, including SoC/SoM platforms used in... ...hardware, software, and quality teams Provide technical leadership...Senior
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Sr. Software Engineer (Operational Systems Team). Be the first to apply!
- software engineer internship Denver, CO
- software development engineer aws Denver, CO
- software developer internship no experience Denver, CO
- real time software engineer Denver, CO
- financial software developer Denver, CO
- part time software developer Denver, CO
- graduate software developer Denver, CO
- software engineer travel Denver, CO
- experienced software developer Denver, CO
- remote entry level software developer Denver, CO




