Medical Science Liaison/Senior Medical Science Liaison, Rare Diseases (Chicago)

Medical Science Liaison / Senior Medical Science Liaison, Rare Diseases (Chicago)

At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture that sparks bold thinking and strengthens our connections with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit and follow Agios on LinkedIn and X.

The impact you will make

Agios Pharmaceuticals is searching for a dynamic MSL/Sr. MSL to join our growing Medical Affairs team. We want someone who cares about this important work and who’s driven to connect to our mission of helping patient communities. The MSL/Sr. MSL will be responsible for key opinion leader (KOL) development within hemolytic anemias, including thalassemia, sickle cell disease (SCD), Pyruvate Kinase Deficiency (PK Def) and myelodysplastic syndrome (MDS) to improve patients’ lives. The MSL will conduct scientific exchange with KOLs in supporting Global Medical Affairs goals and objectives. The MSL will play a critical role in managing investigator & company sponsored studies. The MSL will be their own territory manager in supporting payers and commercial counterparts within appropriate legal/compliance guardrails.

What you will do

• Maintain clinical, scientific, and technical expertise in relevant molecule and disease state areas.
• In collaboration with the MSL director, develop and track opinion leader engagement plans – identify, develop, and maintain long‑term collaborative relationships with OLs within assigned areas. Participate in medical & scientific exchanges with the medical/scientific community including advisory boards.
• Respond to and document unsolicited requests for information on Agios molecules and clinical programs.
• Collaborate with clinical operations and development to support the recruitment of potential clinical trial sites and serve as a local Agios resource to clinical teams at trial sites participating in Agios studies as requested.
• Facilitate company sponsored and investigator sponsored trials (ISTs). Provide medical/clinical teams with feedback and insights from interactions with investigators and payers.
• Represent the company at medical meetings through Medical Affairs’ Scientific Booth coverage and other related activities.
• Adhere to corporate SOPs and ensure vigilant compliance with relevant legal and regulatory guidelines governing scientific interactions with physicians and healthcare professionals across all activities, including those related to clinical trials, scientific interactions with internal and external groups, and responses to unsolicited requests for medical/scientific information.
• Embrace and demonstrate the Agios culture of absolute integrity, focused execution, incisive leadership, collaborative spirit and pursuit of excellence and innovation.

What you bring

• An advanced clinical degree (e.g., PharmD, PhD, or MD – other doctoral degrees may be considered) is strongly preferred.
• Industry experience with a minimum of one year of relevant hematology clinical/research/industry experience in a clinic setting or rare diseases.
• Virtual or in‑person meetings are facilitated as needed. Travel may be up to 70% of time, including frequent overnight stays and, where required, global travel.
• Exhibits the highest level of scientific and clinical acumen with excellent communication and networking skills.
• Team‑minded with an ability to be innovative and flexible in a fast‑paced, changing environment.
• Understanding of, and experience with, the regulatory framework applicable to interactions with healthcare providers, payers, advocacy and other business partners.
• Previous MSL experience preferred.
• Proficiency in an additional language preferred (Mandarin, Cantonese, Hindi, Arabic, Vietnamese).

Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening!

Work Location

Location Specific – Field/Remote: This is a remote‑based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in‑person presence expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events.

What we will give you

• Deliberate Development. Your professional growth is one of our top priorities.
• Flexibility. We’re all about individual needs, embracing different perspectives, work styles, health and wellness approaches, family care, and productivity. When you’re at your best, we’re at our best.
• Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well‑rounded and flexible to help meet varied personal and professional needs of every member of our team. For more detail on the benefits we offer, visit Inside Agios section of our website.
• Competitive and equitable performance‑based compensation. This includes base salary and both short‑ and long‑term incentives that are connected to our business strategy and vary based on individual and company performance.
  • The current base salary range for an MSL is expected to be between $153,541 and $230,312 annualized and for a Sr. MSL between $183,549 and $275,324 annualized; final salary will be determined based on various factors including years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators.
• Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data‑informed risks to help push the boundaries.
• Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce.
• Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.