US Medical Affairs Lead, Anti-Infectives

Site Name: Durham Blackwell Street, Philadelphia Walnut Street Posted Date: Mar 20 2026 Job Title: US Medical Affairs Lead, Anti‑Infectives Location: Durham, NC or Philadelphia, PA At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating substantial assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. The US Medical Affairs Lead, Anti‑Infectives is accountable for overall US medical strategy and achievement of the tactical objectives to support launch. This leader is responsible for ensuring strategic alignment across the organization and representing US needs to ensure patients have access to and can benefit from its scientific advancements and innovation. You will lead Medical Affairs activities across the United States, shaping medical strategy, evidence planning, and external engagement. You will work closely with global teams, commercial partners, and clinical development. We value clear communicators and innovative thinkers who put patients first, collaborate across functions, and drive measurable impact. This role offers career growth, visible influence, and work that aligns with our mission of uniting science, technology and talent to get ahead of disease together. Key Responsibilities Accountable for US medical asset strategy and execution for all medical activities in the US driving effective alignment and synergy across the GSK enterprise where applicable. Medical leader on the Integrated Business Commercialization Team (IBCT) for Anti‑Infections in the US representing the medical strategy and perspective and ensuring alignment to the commercial asset strategy as appropriate. Serves as a core member of the Global Medical Team to develop the global medical asset strategy, evidence generation plan, and integrated communication plan. Represents the US perspective at global leadership team meetings, bringing a strong view on US customer needs and access considerations. Leads the cross‑functional Medical Matrix Team to strategically plan, create action plans based on incoming insights, track progress and measure impact against the medical plan throughout the year. Has in‑depth understanding of the medical unmet needs and strategically aligns activities and innovation to measurably address them. Working with Therapy Area Head ensures strategic alignment of asset positioning and evidence planning with the overall therapeutic portfolio and disease area strategies. Leads medical engagement between GSK and external communities to advance scientific and medical understanding including the appropriate development and use of our medicines, the management of disease, and patient care. Coordinates with the field medical, payer, and policy teams on engagement plans and objectives to achieve asset communication goals and outcomes. Working in concert with the US real‑world evidence team, accountable for local evidence generation planning. Overall budget accountability for the asset in the US. Prioritizes investments to achieve measurable outcomes for patients. Effectively manages and professionally develops multiple medical staff reporting directly into role. Applies sound medical governance for all activities and is accountable for medical governance oversight and sign off for all asset activities. Basic Qualifications Advanced scientific or clinical degree such as MD, PharmD, PhD, or equivalent. Eight or more years of experience in relevant therapeutic area. At least 5 years of pharmaceutical industry experience with Medical Affairs responsibilities. Five or more years of experience developing medical strategy and evidence generation plans, and to deliver against asset operational plans. Preferred Qualifications Robust knowledge of the US healthcare environment including disease‑specific research priorities, public health need, competitor landscape, clinical practice trends and treatment guidelines evolution. Clinical research/drug development experience obtained while working in the pharmaceutical industry or substantial clinical trial experience collaborating with pharmaceutical sponsors in either the academic or clinical practice setting is desirable. Experience working effectively in a matrix environment. Strong stakeholder engagement and external scientific communication skills. Excellent written and verbal communication skills in English. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at View email address on click.appcast.io. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. #J-18808-Ljbffr GSK