Lead Project Manager-Clinical Operations
$115.2k - $158.4kHumana
Become a part of our caring community
The Lead Project Manager serves as a strategic leader responsible for overseeing large, complex, and highly visible programs that span multiple workstreams, business areas, and stakeholders. This role drives program execution, executive alignment, governance, risk management, and cross-functional coordination while mentoring project managers and elevating overall PMO delivery capabilities. The Lead PM partners closely with business and operational leaders to ensure initiatives achieve intended outcomes, deliver organizational value, and support enterprise priorities.
Key Responsibilities:
- Lead large, complex, and strategically important programs spanning multiple business areas and workstreams.
- Lead through influence rather than positional authority, building alignment, driving accountability, and securing commitment from cross-functional teams, business leaders, and stakeholders to achieve program objectives.
- Drive program planning, execution, governance, and delivery to achieve business outcomes and organizational objectives.
- Manage program-level risks, issues, dependencies, and resource constraints across multiple initiatives.
- Partner with executive and senior leaders to align priorities, facilitate decision-making, and maintain stakeholder engagement.
- Develop and present executive-level status updates, dashboards, and recommendations to support informed decision-making.
- Coordinate cross-functional teams to ensure successful integration of people, processes, technology, and operational readiness activities.
- Establish and maintain program governance, escalation pathways, and delivery standards aligned with PMO best practices.
- Drive alignment between strategic objectives, program planning, and execution to ensure initiatives deliver measurable business value, achieve targeted outcomes, and support organizational priorities.
- Mentor and coach project managers to strengthen delivery capabilities, consistency, and PMO maturity.
- Identify opportunities for continuous improvement and implement solutions that enhance project and program delivery performance.
- Support portfolio planning and prioritization efforts to ensure resources are aligned to the organization's highest-value initiatives.
Use your skills to make an impact
Required Qualifications
- 5+ years of project and/or program management experience , including direct leadership of large, complex, cross-functional initiatives with enterprise-wide impact.
- Demonstrated ability to influence and lead without direct authority , building alignment and driving accountability across business, operational, and technology stakeholders.
- Experience managing multiple concurrent projects or programs , including governance, risk management, dependency tracking, resource planning, and executive communications.
- Strong strategic thinking and business acumen , with a proven ability to align program execution to organizational objectives and measurable business outcomes.
- Excellent communication and stakeholder management skills , including experience presenting to senior leaders, facilitating decision-making, and providing executive-level reporting and recommendations.
Preferred Qualifications
- PMP, PgMP, Agile, SAFe, or other project/program management certifications.
- Experience leading organizational transformation, process improvement, or large-scale operational initiatives.
- Experience coaching and mentoring project managers to improve delivery capability and PMO maturity
Additional Information
Interview Format
As part of our hiring process, we will be using an exciting interviewing technology provided by HireVue, a third-party vendor. This technology provides our team of recruiters and hiring managers an enhanced method for decision-making.
If you are selected to move forward from your application prescreen, you will receive correspondence inviting you to participate in a pre-recorded Voice Interview and/or an SMS Text Messaging interview. If participating in a pre-recorded interview, you will respond to a set of interview questions via your phone. You should anticipate this interview to take approximately 10-15 minutes.
Work-At-Home Requirements:
- WAH requirements: Must have the ability to provide a high-speed DSL or cable modem for a home office. Associates or contractors who live and work from home in the state of California will be provided payment for their internet expense.
- A minimum standard speed for optimal performance of 25x10 (25mpbs download x 10mpbs upload) is required.
- Satellite and Wireless Internet service is NOT allowed for this role.
- A dedicated space lacking ongoing interruptions to protect member PHI / HIPAA information
Scheduled Weekly Hours
40Pay Range
The compensation range below reflects a good faith estimate of starting base pay for full time (40 hours per week) employment at the time of posting. The pay range may be higher or lower based on geographic location and individual pay will vary based on demonstrated job related skills, knowledge, experience, education, certifications, etc.$115,200 - $158,400 per yearThis job is eligible for a bonus incentive plan. This incentive opportunity is based upon company and/or individual performance.Description of Benefits
Humana, Inc. and its affiliated subsidiaries (collectively, “Humana”) offers competitive benefits that support whole-person well-being. Associate benefits are designed to encourage personal wellness and smart healthcare decisions for you and your family while also knowing your life extends outside of work. Among our benefits, Humana provides medical, dental and vision benefits, 401(k) retirement savings plan, time off (including paid time off, company and personal holidays, paid parental and caregiver leave), short-term and long-term disability, life insurance and many other opportunities.Application Deadline: 11-29-2026
About us
About Humana: Humana Inc. (NYSE: HUM) is a leading U.S. healthcare company. Through our Humana insurance services and our CenterWell healthcare services, we make it easier for the millions of people we serve to achieve their best health – delivering the care and service they need, when they need it. These efforts are leading to a better quality of life for people with Medicare and Medicaid, families, individuals, military service personnel, and communities at large. Learn more about what we offer at Humana.com and at CenterWell.com.
Equal Opportunity Employer
It is the policy of Humana not to discriminate against any employee or applicant for employment because of race, color, religion, sex, sexual orientation, gender identity, national origin, age, marital status, genetic information, disability or protected veteran status. It is also the policy of Humana to take affirmative action, in compliance with Section 503 of the Rehabilitation Act and VEVRAA, to employ and to advance in employment individuals with disability or protected veteran status, and to base all employment decisions only on valid job requirements. This policy shall apply to all employment actions, including but not limited to recruitment, hiring, upgrading, promotion, transfer, demotion, layoff, recall, termination, rates of pay or other forms of compensation and selection for training, including apprenticeship, at all levels of employment.
- Quantum Technologies LLC in Raleigh, NC seeks a Senior Project Manager to lead complex, high-impact operations projects across finance, contracts, staffing, and external communications. This role requires applying formal project management methodologies and coordinating...SuggestedRemote job
$50k
...Lead Project Manager, Marketing Operations Reynolds American is evolving into a global multi-category business. Our purpose is to create A Better Tomorrow™ by Building a Smokeless World. To achieve our ambition, we are looking for colleagues who are ready to join us...SuggestedFull timeTemporary workFor contractorsLocal areaFlexible hoursShift work- Beacon Hill is seeking a mid-level Project Manager for Healthcare Delivery (Operations) in a 100% remote, contract-to-hire role. Eligibility for conversion to direct hire at the end of the contract is limited to individuals residing in the following states: Alabama, Delaware...SuggestedRemote jobContract work
- ...ContractPosted: 2026-11-04Deadline: 0001-01-01L4/L5 - Pod Lead (Operation Manager/Data Delivery Program Manager)No remote work available, assigned... ...Los AngelesJob ResponsibilityManages and drives assigned projects end to end, working with the technical program manager...SuggestedRemote work
$160k - $190k
...aspire to alter the course of lives. The Sr. Clinical Program Manager provides overall clinical project management direction, appropriate prioritization... .... This person will be in charge of a clinical operations team leading multiple studies in support and alignment with...SuggestedFull timeWork experience placementWorldwideFlexible hours- Overview Contracts Manager- Clinical Site Contracting Location: US... ...are directly billable to project, supporting business development... ..., finance, procurement and operations teams to ensure contracts... ...improvements in contract workflows. Lead contract negotiations with...Full timeContract workFor subcontractorLocal areaRemote work
$118.6k - $158.6k
...Description: The Contract Manager is directly responsible for the... ...negotiation processes for clinical site contracts and ensures final... ...with the BeiGene Clinical Operations team and legal team on-site/investigator... ...or equivalent at a Project level to ensure contracts in...Hourly payFull timeContract workWork experience placementWork at officeLocal area$110k
Premier Research is looking for a Manager, Clinical Operations to join our Clinical Monitoring, Site Management... ...resources and employee resource projections to ensure that project teams meet... ...interpersonal skills able to work and lead efficiently within a matrix environment...Full timeNight shift$107.7k - $199.3k
...Position Purpose : The Manager of Clinical Pharmacy Operations is responsible for developing, implementing and administering clinical pharmacy tools and programs to support corporate and regional drug utilization and financial goals. Key Detail s: This position is...Full timePart timeWork at officeRemote workFlexible hours$120k - $165k
...listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Senior Manager, Clinical Operations – Operational Excellence based in the... ...Operational Excellence will design and lead the operational systems that help...Full timeImmediate startRemote work$145k - $165k
...The Senior Manager, Clinical Operations leads day-to-day operations across Salma Health clinics and manages the Clinical Operations Managers and Practice... ...set by the Clinical Leadership. Run improvement projects in patient flow, scheduling, throughput, and compliance....Full timeLocal areaRemote work$115k - $180k
...Office Job Description Join Us as Manager Clinical Operations – Make an Impact at the Forefront of Innovation... ...and key performance indicators to lead performance. You will act as point-of-... ...process. Supports activities of project leads/functional leads to optimize the...Full timeTemporary workWork at officeLocal areaRemote work- ...’re looking for an experienced people manager to lead our fast-growing Medical Office Assistant... ...the team for new launches, optimize operational workflows, and support strategic... ...This role reports to the Senior Manager, Clinical Operations, and works closely with our...Work at officeRemote workShift workWeekend workAfternoon shift
- ...Manager, Clinical Operations Join us as a Manager, Clinical Operations - And take on a leadership role... ...Team Leadership & Development • Lead, support, and develop a team of Clinical... ...and study priorities. • Partner with project and functional leads to optimize operational...Local areaRemote work
- ...Clinical Research Manager Manage a team of clinical staff working in support... ...clinical studies to ensure projects are appropriately resourced... ...findings as outlined by clinical operations management. May... ...and clients. IQVIA is a leading global provider of clinical...Immediate startRemote workWorldwide
- ...Manager, Clinical Operations At ICON Strategic Solutions, you will work in a sponsor-dedicated model... ...Key responsibilities include: Leading the operational planning and execution... ...dynamic environment. Proficiency in project management tools and methodologies,...Remote workWorldwide
- ...Position Summary The Senior Manager/Director Clinical Operations will be responsible for oversight and management of up to 2 early phase clinical programs in collaboration with the selected Clinical Research Organization (CRO). Primary Responsibilities: Create...Contract workRemote workFlexible hours
$130k - $150k
...CTG is seeking an experienced Senior Project/Program Manager to lead the establishment and ongoing... ...Service Delivery (SD) tower supporting Clinical Applications within a healthcare environment... ...required for successful ongoing operations. The ideal candidate brings a...Contract workLocal area- ...Emmes is seeking a Senior Biostatistician Manager for a remote role to oversee statistical... ...Managers, ensuring timely completion of projects, and serving as a client point of... ...candidate will have significant experience in clinical research leadership, a Master’s or PhD...Remote work
$120.8k - $201.3k
...Summary The Behind the Meter (“BTM”) Lead Contract Manager will provide strategic and hands-on commercial... ...Portfolio, with a primary focus on project execution, contract negotiation and... ...Management, Legal, Finance, and Operations teams to align on contract execution strategy...Full timeContract workFor subcontractorRemote workRelocation package- ...: PR/612976_1791225177Senior Contracts Manager - Clinical & SurgicalLocation: Nashville, TN (Hybrid... ...Manager - Clinical & Surgical to lead strategic sourcing and contract negotiations... ...cost savings, quality, and operational objectives.Negotiate pricing, rebates,...Contract workWork at officeRemote workRelocation package
$125k - $135k
...to assess cognition across clinical trials, healthcare settings,... ...spanning psychology, data science, operations, and technology - works... ...why we’re seeking a Senior Project Manager accountable for managing multiple... .... Independently lead Cogstate’s complex global clinical...Full timeTemporary workWork at officeLocal areaRemote workFlexible hours- ...Serve as the clinical PM for the EHR Transformation... ...0 clinics. Own and manage the end-to-end clinical... ...Partner with Domain Design Leads on clinical design and... ...and management of project delivery related to the... ...assist with business operations and development, providing...Full timeFor contractorsWork experience placementFor subcontractorLocal area
$151.2k - $207.93k
Company DescriptionGuardant Health is a leading precision oncology company focused on... ...) and Facebook. About the Role:The Manager of Clinical Operations is responsible for the technical... ...supervision to laboratory personnelStrong project management abilities.Work...Full timeWork at officeLocal areaWork from home$150k - $175k
...position is responsible for leading a growing team to... ...development, and execution of clinical trials in collaboration with Clinical Operations and cross-functional... ...role combines people management with hands-on... ...to support new clinical projects at all phases of development...Minimum wageOngoing contractFull timeContract workTemporary workWork at officeLocal areaRemote workWorldwideNight shift3 days per week- Connections Health Solutions is seeking an Operations Project Manager to coordinate cross-functional healthcare and clinical operations initiatives across the crisis network. You will manage scope, schedule, budget, risk, and change, delivering projects on time with quality...Remote job
$120k - $200k
...Senior Product Manager - Veeva Clinical Operations Veeva Systems is a mission-driven organization and pioneer in industry cloud, helping life sciences... ...a unique opportunity to shape the future of an industry-leading product suite and have an impact on global health....Work at officeLocal areaRemote workWork from homeFlexible hours$96k - $144k
...Remote/Hybrid Job Overview We’re looking for a Senior Project Manager to lead high-impact, enterprise-wide initiatives at the... ...managing cross-functional testing cycles, and strengthening operational rigor across the organization. In parallel, you’ll drive strategic...Full timeRemote work$130k - $145k
...Purpose and Scope This Senior Project Manager position, under minimal supervision, is accountable for leading and managing multiple strategically-focused projects simultaneously... ...leads of strategic projects within Tolmar Operations including, but not limited to, MS&T, Supply...Full timeWork at officeLocal areaRemote workHome office$77.6k - $176k
Contracts Manager, LeadThe Opportunity: As a contract manager on our team, you will use your knowledge to capture, implement, and manage... ...-specific affordability and organizational requirements. The projected compensation range for this position is $77,600.00 to $176,000....Full timeContract workPart timeWork at officeLocal areaRemote work
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Lead Project Manager-Clinical Operations. Be the first to apply!
- planning project manager Remote
- integrated project manager Remote
- director project management office Remote
- project manager life sciences Remote
- project manager supervisor Remote
- nuclear project manager Remote
- project manager full time Remote
- public health project manager Remote
- project manager health Remote
- structural project manager Remote



