Senior/Principal Process Engineer

Job ID: R-108856Company: LillyLocation: Lebanon, Indiana, United States of AmericaJob Type: Full TimeCategory: EngineeringPosted Date: 2026-07-20At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Lilly is currently constructing an advanced manufacturing facility for production of advanced therapy medicinal products (ATMPs) located in Lebanon, IN. This facility is intended to provide current and future products, including new modalities. This is a unique opportunity to be a part of the startup team for a greenfield manufacturing site, and the successful candidate will help to build the processes and facility to enable a successful startup into GMP manufacturing operations. We are seeking Process Engineers to support the ATMP Manufacturing Business in Lebanon. Process Engineering is core to delivering our product pipeline across batch and continuous API production and development.ResponsibilitiesFacility Start-up:Provide Process Engineering support to the Global Facility Delivery team (Lilly’s Global Large Scale Capital Delivery Team) with a strong focus on right first time and on schedule facility start-up (e.g. design reviews, process safety assessments, User Requirements, C&Q support, unit operation shakedown and startup, facility operational readiness) Define and own relevant aspects of the overall integrated Operational Readiness Plan (e.g. SOP development, maintenance strategy, automation optimization, pre-startup safety reviews, alarm requirements, Performance Qualification requirements/protocol development, etc.) Own the Performance Qualification execution for area of responsibility Develop and implement unit operation and equipment control strategy to sustain and optimize API processes.Support initial Operations Training requirements as the Equipment and Area SME Lead/support the tech transfer of new processes into the facility Facility Operations:Provide process engineering support in batch API supply or continuous platforms through application of chemical engineering fundamentals.Monitor, assess and document equipment performance to maintain ongoing qualification.Develop and maintain the basis of safety for process equipment.Integrate mechanistic modelling, process simulation and analysis into current and future processes to enhance process understanding and control.Identify and implement continuous improvement opportunities related to equipment and processes as core member of cross-functional process team.Lead/support the tech transfer of new processes and unit operations across batch and continuous processing platforms.Utilize root cause analysis techniques to investigate process and equipment issues and deliver robust and sustainable corrective and preventative actions.Basic QualificationsBachelor's Degree in Chemical, Biochemical, Pharmaceutical, Biomedical, or Mechanical Engineering3+ years of relevant experience in manufacturing operations (prefer chemical, pharmaceutical)Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.Additional Skills/PreferencesDeep technical interest and understanding in the field of Chemical Engineering.Experience in ATMP manufacturing.Strong analytical and problem solving skills.Ability to work on own initiative and as part of a Process Team consisting of a diverse group of management, production, science and engineering professionals.Creativity to identify improvement opportunities and the tenacity/initiative to see them implemented.Guidance/mentoring of others through processes.Flexibility to meet business needs.Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form () for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (View email address on click.appcast.io), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is$66,000 - $171,600Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.#WeAreLillySkillsprocess engineeringgmp compliancechemical engineeringfacility start-upperformance qualificationprocess safety assessmentunit operation designchemical process optimizationcontinuous improvementroot cause analysisatmp manufacturingmechanistic modellingprocess simulationprocess analysisequipment control strategychemical engineering fundamentalsbatch manufacturingcontinuous manufacturingtech transferoperations trainingcross-functional team leadershipanalytical skillsproblem solvingprocess improvement