Principal Scientist, GEM Molecular Validation & Automation
Biopharma Careers
Amgen in South San Francisco is seeking an experienced Principal Scientist to advance the GEM Molecular Validation program, providing hands-on expertise in genome engineering, molecular characterization, and assay development. You will lead orthogonal genotyping, long-read sequencing, and AI-enabled data analysis, collaborating across teams to improve GEM quality and throughput while upholding animal-welfare standards. #J-18808-Ljbffr Biopharma Careers
- Amgen seeks a highly skilled Principal Scientist to lead GEM molecular characterization and validation. You will advance CRISPR‑based model generation, orthogonal QC, and sequencing workflows, enabling scalable, AI‑driven analysis. The role requires deep experience with...MolecularPrincipal
$165.64k - $224.1k
...the lives of patients while transforming your career. Principal Scientist - GEM Molecular Validation & Technologies What you will do Let's do this. Let's... ...building scalable GEM capabilities through sequencing, automation, computational approaches, and emerging AI-enabled...MolecularPrincipalFlexible hours- Amgen is seeking a Principal Scientist to support and advance the GEM program, focusing on molecular characterization of genetically engineered models from generation to... ...colony establishment. You will drive sequencing, validation, and AI-enabled analysis to improve model...MolecularPrincipal
$177k - $235k
...Description:We are seeking an innovative Principal Scientist to bridge the gap between traditional... ...predictions are rigorously validated and that the resulting biological data... ...discovery.Position Requirements:Ph.D. in molecular biology, biochemistry, computational modeling...MolecularPrincipal$155k - $180k
...seeking a highly motivated Principal Scientist to lead the Pilot Plant function... ...implement closed, aseptic, automation strategies, including... ...Bioengineering, Biochemistry, Molecular & Cell Biology, Immunology... ...(IND/BLA) and process validation (PPQ).Proven track record of...MolecularPrincipalFull timeInternshipLocal area$144.9k - $269.1k
...advanced computational methods, including molecular dynamics and affinity prediction, for... ...complex modeling, ligand discovery, validation and optimization. AI/ML for Drug Discovery... ...and project teams, including wet-lab scientists.Cross-Functional Collaboration: Work closely...MolecularPrincipalFull timeLocal areaRelocation package$202.5k - $236.25k
...expertise in structure-guided drug design, molecular modeling, molecular dynamics and... ...include guiding programs from initial target validation stages through to candidate... ...experience working collaboratively with scientists and engineers ~ Strong foundational...MolecularPrincipal$155k - $200k
...scale. This Position NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development... ...knowledge of bioanalytical method qualification/validation principles for PD biomarker measurements, including...MolecularPrincipal- ...in South San Francisco is seeking a Scientist I to support the development of next‑... ...optimize assay development, workflow automation, and validation readiness in a collaborative, fast‑paced... .... The ideal candidate has hands‑on molecular biology and NGS experience, and a passion...Molecular
$159.6k - $251.2k
...seeking a highly motivated Associate Principal Scientist to join a bicoastal Discovery Oncology... ...Ph.D. in Cancer Biology, Immunology, Molecular Biology, Biochemistry, Oncology, or a... ...techniques for target identification and validation, including but not limited to RT-PCR,...MolecularPrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$173.1k - $321.5k
...that we all have more time with the people we love.The Senior Principal Scientist serves as the scientific leader for Bioanalytical Strategy... ...knowledge of bioanalytical methodologies, including flow cytometry, molecular assays (qPCR/ddPCR), ligand-binding assays, functional...MolecularPrincipalFull timeLocal areaRelocation package$155k - $180k
...more patients.About the role:Allogene Therapeutics is seeking Principal Scientist, Cell Starting Material - Process Sciences group within the... ...as assigned.Position Requirements & Experience:Ph.D. in Molecular & Cell Biology, Immunology, or a related field with at least...MolecularPrincipalFull timeLocal area$147.8k - $274.4k
...Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more... ...motivated and collaborative Senior/Principal Machine Learning Scientist to join the... ...variety of different data modalities such as molecular structures, omics data, images, and...MolecularPrincipalFull timeLocal areaWorldwide$143.2k - $265.9k
...Oncology at Genentech is excited to announce an opportunity for a Principal Scientist, Lab Head, to join the Synthetic Immunity division... ...profiling of T and other immune cells (e.g. multiparameter flow, molecular profiling, etc.)Relocation benefits are available for this...MolecularPrincipalFull timeLocal areaRelocation package$150.7k - $279.9k
...and analyzes their structures and molecular interactions. We collaborate with scientists throughout the Research and Drug... ....The OpportunityAs a Principal Scientist in Structural Biology,... ...design, computational or laboratory automation, or related topics.Together, we’...MolecularPrincipalFull timeWork at officeLocal areaWorldwideRelocation package$167.4k - $310.8k
...Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more... ...techniques. We are seeking a Senior or Principal Machine Learning Scientist to join the... ...systems.PreferredExperience with molecular modalities (e.g., protein sequences, chemical...MolecularPrincipalFull timeLocal areaWorldwideRelocation package$143.2k - $265.9k
...seeking a creative and highly motivated Principal Scientist, Medicinal Chemist to join our R&D... ...Proven mastery of both SPPS (manual and automated) and complex solution-phase organic synthesis... ...(Schrödinger, MOE, Maestro) for molecular dynamics, conformational sampling, and...MolecularPrincipalLocal areaRelocation package$71.25k - $187k
...join us. JOB DESCRIPTIONPosition: Senior/Principal Scientist, Discovery Oncology (in vivo Biology)... ...and in vitro assays — to identify and validate novel druggable oncology targets, de-... ...:MS in biology, cancer biology, molecular biology, cell biology, biochemistry or...MolecularPrincipalFull timeH1bVisa sponsorshipWork visaFlexible hours$168.6k - $313k
...experienced Medicinal Chemist (Senior Principal Scientist) to join our innovative research and development... ..., including proficiency in both automated solid-phase peptide synthesis, and... ...including conformational sampling and molecular dynamics (MD) simulations. Proficiency...MolecularPrincipalLocal areaRelocation package$200k - $240k
...delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Principal Scientist, Potency, you will report to the Sr. Director, Head of Molecular and Potency Method Development. You will either lead or support the development and...MolecularPrincipalTemporary workWork at officeImmediate startWeekend work- About the Role Onsite (South San Francisco, CA). Principal Scientist, Potency; reports to Sr. Director, Head of Molecular and Potency Method Development. Responsibilities Develop and qualify pivotal stage potency, immunoassay, and other cell-based methods to support characterization...MolecularPrincipalWork at office
$201.3k - $373.8k
...Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more... .... We're looking for an exceptional Principal Scientist who can architect how our computational... ...operating procedures (SOPs) and automated workflows that portfolio teams actually...PrincipalFull timeLocal areaWorldwide$90k - $210k
...are seeking an innovative and highly motivated Supervising Principal Scientist with expertise in cell therapy process development and people... ...platform that delivers true walk-away, end-to-end automation. Cell Shuttles will be deployed in Cellares’ Smart Factories...PrincipalFull timeFlexible hours- ...health through next-generation molecular diagnostic testing. They are... ...that integrates advanced automation, digital LIMS platforms, and... ...testing. Clinical Laboratory Scientist (CLS) II Title: Clinical... ...leadership. Assist with assay validation and technology transfer for...MolecularWork at officeMonday to FridayShift work
- ...Instagram,XandYouTube. Job Description The Molecular Profiling and Drug Delivery (MPDD)... ...regulatory submissions. Drug Delivery scientists within AbbVie's MPDD organization work... ...withexpertiseinassay development,chemical automation, and integrated workflow design foran...MolecularTemporary workLocal area
$170k - $240k
...Description:Calico is seeking a machine learning scientist to join a research group investigating... ...to biological mechanisms — designing validation experiments, analyzing large-scale... ...and statisticsSubstantive knowledge of molecular biology and genetics; familiarity with...Molecular- ...and generate summary tables and charts.Perform verification and validation of new instruments following written SOPs.Present experiment... ...CE technologies.Good bench work and record keeping skills in molecular biology laboratory.Ability to understand and follow instructions...MolecularContract workWork at officeImmediate start
$103.4k - $192k
...have a great opportunity for a talented Scientist to join our Animal Genetic Technologies... ...of novel modifiers of disease and validation of new targets for therapeutic intervention... ...degree, or equivalent, in genetics and/or molecular biology, with relevant postdoctoral...MolecularFull timeLocal areaRelocation package$85.5k - $158.7k
...seeking a highly motivated and collaborative Scientist 2, Neuroscience Discovery & iPSC Assay... ...:Bachelor’s degree in Cell Biology, Molecular Biology, Neuroscience, or a related... ...delivery, clone isolation, and genomic validation).Experience with arrayed or pooled CRISPR...MolecularFull timeLocal areaRelocation package- ..., a global diagnostics company, seeks a Scientist I in South San Francisco to advance MRD... ...experimental studies, optimizing workflows, automation, and validation readiness in a fast-paced, lab-based setting. You will apply molecular biology and NGS knowledge, contribute to...Molecular
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