Associate Director, Quantitative Pharmacology

A global biopharmaceutical company on a mission to solve unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first‑in‑class medicines in Hematology, Oncology, and Inflammation & Autoimmunity. Headquartered in Wilmington, Delaware, Incyte operates in North America, Europe, and Asia. Job Summary (Primary Function) We are seeking a pharmacometrician to join our Clinical and Quantitative Pharmacology organization in Translational Medicine. An Associate Director is responsible for executing the pharmacometrics strategy and model‑based analyses for clinical drug development, supporting programs and developing and implementing model‑informed drug development (MIDD) strategies to optimize decision‑making across all phases of drug development. Essential Functions Of The Job (Key Responsibilities) Independently conduct and report model‑based analyses including population pharmacokinetics (PK) and pharmacokinetics/pharmacodynamics (PK/PD), exposure‑response modeling, model‑based meta‑analyses (MBMA), disease progression modeling, and clinical trial simulation. Identify opportunities where modeling and simulation can advance the understanding of pharmacokinetics, pharmacodynamics, efficacy, and safety across multiple projects. Develop MIDD strategies across multiple programs and disease areas to optimize prospective studies, inform overall clinical development and regulatory strategies in collaboration with partners (clinical pharmacology, biostatistics, regulatory, and clinical development teams). Effectively communicate results, conclusions, and assumptions of pharmacometrics analyses to a variety of audiences to influence the decision‑making process (written and oral presentation). Mentor and guide peers in pharmacometrics methodologies, tools, and their application in clinical drug development. Stay current with scientific advancements and regulatory trends in clinical pharmacology and pharmacometrics, applying the knowledge to advance drug development for the organization. Publish findings in peer‑reviewed journals. Qualifications Ph.D. in Pharmacometrics, Clinical Pharmacology, Applied Mathematics, Statistics, Engineering, or a related field. 3‑5 years of related industry experience. Hands‑on experience in a statistical programming language and pharmacometrics analysis software including R and NONMEM or equivalents. Excellent communication skills and the ability to collaborate with cross‑functional teams. Strong time management and the ability to balance multiple tasks to accomplish program goals. Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required. Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer. #J-18808-Ljbffr Incyte