Senior Research Statistician - Discovery & Exploratory Analysis (Hybrid)

About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. The Senior Research Statistician is responsible for providing statistical support to the research and development organizations for drug discovery, target identification/verification, non-clinical and clinical biomarker exploration to characterize subgroups of patients or markers of disease progression and treatment response for precision medicine. The Senior Research Statistician works under supervision to support discovery researchers, translational scientists and clinicians in the design, collection, analysis and reporting of multi-dimensional biomarker data from Discovery to late stage clinical development to enable objective decision-making for each drug development program. Major Job Responsibilities Collaborating with discover and translational biomarker scientists and clinicians and contribute to design, analysis and reporting of biomarker and assay studies in association with early and late phase clinical trials. The typical analysis includes pharmacodynamic biomarker analysis, safety biomarker analysis, prognostic and predictive biomarker identification and development, bioassay and companion diagnostic test development, patient subgroup identification based on biomarkers and clinical variables. Contributing to design, analysis and reporting of biomarker-based clinical trials or other scientific research studies. Assist in developing biomarker section of clinical trial protocols or biomarker analysis plans. Working under supervision to implement sound statistical methodology in scientific investigations. Ensuring data are sensible and comprehensive with quality for the assigned statistical analysis and deliverables. Supporting and advising scientists in discovery and translational science units in the design, analysis and reporting of in vitro, in vivo pharmacology studies, and human clinical trials under supervision. Identify markers and signatures from internal/external omics/imaging and other biomarker data for target identification, mechanism of action, resistant mechanism, disease progression, patient selection and stratification for precision medicine. With Supervision perform statistical analyses as per the biomarker analysis plan. Bringing attention to supervisor and team for potential issues arising in the study design; conducting and proposing scientifically sound approaches. If assigned, evaluating appropriateness of available software for planned analyses and assessing pros and cons for potential development of novel statistical methodology. Accountability for data presentation and inference, with supervision. Collaborating in publication of scientific research. Ensuring that study results and conclusions are scientifically sound, clearly presented, and consistent with statistical analyses provided. Clearly explaining statistical concepts to non-statisticians. Provide responses to questions and pursue analyses suggested by data under supervision. Supporting communications between assigned product team(s) and functional management. Minimum Job Qualifications: MS (with 4+ years of experience) or PhD (with 0+ years of experience) in Statistics, Biostatistics, or a highly related field. Research experience in the pharma or healthcare space Experience with Machine Learning Preferred Qualifications Experience with Biomarker Research Other Required Skills: High degree of technical competence and effective communication skills, both oral and written Able to identify data or analytical issues, and assist with providing solutions by either applying own skills and knowledge or seeking help from others Able to build strong relationship with peers and cross-functional collaborators to achieve higher performance. Highly motivated to drive innovation by raising the bar and challenging the status quo Able to integrate high dimensional data from different sources. Familiar with overfitting and multiple testing control methods, such as cross-validation and random resampling techniques. Familiar with machine learning and predictive modeling methods. Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible toparticipatein our short-term incentiveprograms. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssole andabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: #J-18808-Ljbffr AbbVie