Postdoctoral Fellow or Staff Scientist - Protein Chemistry, Crystallography and Structure Deter[...]

Position: Postdoctoral Fellow or Staff Scientist at John Williams research lab, Beckman Research Institute, City of Hope. Research primarily focuses on structural and biophysical methods to identify sources of energy additivity and multivalency in macromolecular complexes and to develop new tools and novel therapeutics. Responsibilities Determine structure of modified antibodies with immune receptors Apply yeast display to stabilize and subsequently deimmunize proteases Create additional antibody variants to maximize therapeutic activity in a clinical setting Qualifications Ph.D. degree in chemistry, biochemistry, structural biology, biophysics or a related discipline is required. Knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection, and structure determination), biochemistry (enzyme kinetics), and biophysics (Surface Plasmon Resonance and Isothermal Titration Calorimetry). Additional Information To apply, send CV or resume to Dr. John Williams at View email address on click.appcast.io for consideration. Candidates will be assessed for the suitable level based on relevant experience. Postdoctoral Fellow – Pay Rate: $34.00 – $37.54 Staff Scientist – Pay Rate: $38.67 – $123.37 City of Hope is an equal opportunity employer. #J-18808-Ljbffr City of Hope