Senior Bioinformatics Scientist

Seeking a highly experienced Senior Bioinformatics Scientist to work remotely, this full-time position will drive the design and development of next-generation minimal residual disease (MRD) laboratory developed tests (LDTs), contributing to assay concepts and collaborating with cross-functional teams to deliver clinically actionable diagnostics. Key Responsibilities Contribute to bioinformatics strategy for MRD assay design, development, and lifecycle management Design and execute analytical studies to evaluate assay performance in collaboration with wet lab and biostatistics partners Partner closely with molecular biology, assay development, QA/RA, clinical, and software engineering teams to ensure alignment with regulatory expectations Required Qualifications Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a closely related quantitative field (or M.Sc. plus 3 additional years of industry experience) Minimum 6 years of relevant experience in biotech, diagnostics, or regulated healthcare environments Demonstrated experience in NGS-based assay development for clinical diagnostics, particularly with ctDNA-based MRD assays Strong programming skills in Python and experience developing reproducible, production-grade analysis pipelines Proven experience working in design-controlled, regulated environments (CAP/CLIA LDT, IVD, or equivalent)