Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior R&D Mechanical Engineer - Scientific Instrumentation

$153.82k - $269.55k

Agilent

Agilent seeks a Senior R&D Mechanical Engineer to lead mechanical design and architecture for advanced scientific instrumentation. The role spans precision mechanisms, vacuum systems, thermal management, and cross-functional collaboration from concept through product release in Santa Clara.

Responsibilities

  • Lead mechanical design and architecture for complex scientific instruments from concept through release
  • Convert scientific and customer requirements into mechanical concepts, specifications, and verified designs
  • Select materials, finishes, adhesives, fasteners, and manufacturing processes for laboratory and vacuum environments
  • Perform thermal, structural, tolerance, and stack-up analyses using engineering calculations and simulation
  • Plan and execute prototype builds, design verification, and root-cause investigations with documentation

Requirements

  • Bachelor's or Master's degree in Mechanical Engineering or equivalent practical experience
  • Minimum 8 years of professional mechanical design experience delivering complex hardware products
  • Strong knowledge of engineering materials, thermal loading, and heat conduction behavior
  • Experience designing laboratory or scientific equipment with attention to cleanliness and environmental factors
  • Proficiency with engineering drawings, geometric dimensioning, tolerance analysis, and design-release practices
  • Experience with machined, sheet-metal, molded, and 3D-printed components and supplier management
  • Advanced CAD proficiency with Siemens NX or comparable parametric 3D platform preferred

Compensation: $153,823–$269,550 base annually plus bonus, stock, and benefits

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Senior R&D Mechanical Engineer - Scientific Instrumentation in San Francisco, CA vacancy
  • $197k - $300k

     ...outcomes, operational advancement, scientific discovery and cutting-edge...  ...difference. We're looking for a Senior Instrumentation and Controls Engineer in San Francisco or Los Angeles,...  ...need • Bachelor’s in Electrical, Mechanical or Chemical Engineering• Minimum... 
    Senior
    Scientific
    Full time
    Work at office
    Remote work

    Jacobs

    San Francisco, CA
    4 days ago
  • $117.8k - $176.8k

     ...contribute innovative ideas, guided by scientific rigor and a vision for sustainable...  ....Stantec is currently seeking an Instrumentation and Controls Engineer for any one of our California state...  ...plans; review and evaluation of mechanical specifications with controls content... 
    Senior
    Scientific
    Full time
    Contract work
    Temporary work
    Part time
    For contractors
    Casual work
    Work at office
    Local area
    Flexible hours

    Stantec

    San Francisco, CA
    3 days ago
  • $150k - $200k

     ...50,000 - $200,000 Benefits : waiting on Job Title: Senior Mechanical Engineer, Exo-organ Devices Overview: Join a bold and interdisciplinary...  ..., communicative, and eager to learn about new scientific fields. Eager to contribute to a company redefining... 
    Senior
    Scientific

    Hirewell

    San Francisco, CA
    3 days ago
  •  ...make biology easier to engineer. Ginkgo is...  ...looking for talented senior engineers who are excited...  ...expertise in CAD and mechanical design, complemented by...  ...operation to translate scientific requirements into robust...  ...technical evaluations of new instruments and components- Mentor... 
    Senior
    Scientific
    Shift work

    Ginkgo Bioworks

    Emeryville, CA
    5 days ago
  • $180k - $210k

     ...Senior Mechanical Engineer The Facilities Division at Lawrence Berkeley National Laboratory is seeking a Senior Mechanical Engineer to join...  ...Evaluate systems' spare capacity and ability to support scientific equipment installations. Develop conceptual designs and... 
    Senior
    Scientific
    Full time
    Part time
    For contractors
    Relocation
    Relocation package

    Lawrence Berkeley Lab

    Berkeley, CA
    4 days ago
  • $158k - $269k

     ...self-driving at scale. Work on a number of end-to-end autonomy engineering tasks from conceptualization, design, implementation to...  ...proficiency and knowledge of Python and C++ internals including scientific computing libraries. Some experience in reading and developing... 
    Senior
    Scientific
    Full time
    Work at office
    Work from home
    Flexible hours

    Waabi

    San Francisco, CA
    3 days ago
  •  ...Role Description We are seeking a curious, hands-on R&D Test Engineer with an instrumentation focus to join our Physical R&D team. You will own the...  ...information: able to plan and execute good tests within a scientific framing that others own, and curious enough to ask the... 
    Scientific
    Local area

    Gridware

    San Francisco, CA
    28 days ago
  • $197k - $300k

     ...outcomes, operational advancement, scientific discovery and cutting-edge...  ...difference. We're looking for a Senior Instrumentation and Controls Engineer in San Francisco or Los Angeles,...  ...ll need Bachelor’s in Electrical, Mechanical or Chemical Engineering Minimum 1... 
    Senior
    Scientific
    Full time
    Work at office
    Remote work

    Jacobs

    San Francisco, CA
    1 day ago
  • $120k

     ...Job Description Job Description Senior Field Service Engineer – Scientific Instrumentation (West Coast) Take your field service career to the next level supporting some of the world's most advanced scientific imaging systems. This is more than a traditional Field... 
    Senior
    Scientific
    Work at office
    Home office

    TEEMA

    San Francisco, CA
    19 days ago
  •  ...Senior Clinical Scientist This is the job title and description for the Senior Clinical Scientist position. The detailed job description...  ...will be responsible for leading and conducting complex scientific research projects. This role requires a deep understanding of clinical... 
    Senior
    Scientific

    Opto Biosystems

    San Francisco, CA
    1 day ago
  •  ...Myeloma to advance US Medical Affairs strategy and execution in a dynamic oncology landscape. You will drive evidence generation, scientific exchange, and launch readiness across cross-functional teams including Field Medical, Commercial, Market Access, HEOR/RWE,... 
    Senior
    Scientific

    Kite Pharma

    San Francisco, CA
    5 days ago
  • Genentech, located in South San Francisco, seeks a Senior Principal Scientist in Translational Safety to provide scientific leadership across drug development, from discovery through clinical development and marketed products. You will integrate toxicology, pathology,... 
    Senior
    Scientific

    Genentech

    San Francisco, CA
    2 days ago
  • $143k - $198k

     ...elevate design, push boundaries and create a more resilient future. The San Francisco office of SmithGroup is looking for a Senior Mechanical Engineer to join our team. Working with us, you will: Serve as the engineering leader through all stages of a project of any size... 
    Senior
    For contractors
    Work at office
    Local area

    SmithGroup

    San Francisco, CA
    6 days ago
  •  ...feedback from the people making scientific and company-defining...  ...fluid handling, laboratory instrumentation, or subcutaneous drug delivery...  ...methods that connect engineering performance to chemical or...  ...at least one relevant area—mechanical design, electrical systems,... 
    Senior
    Scientific
    H1b
    Visa sponsorship

    Capable Labs

    San Francisco, CA
    2 days ago
  •  ...Mechanical Engineer Opportunity At Medra At Medra, we're building an autonomous robotic platform that enables scientists to automate complex...  ...beyond. Our goal is to enable the next biggest leap in scientific discovery, unlocking a world where experimental data... 
    Scientific
    Relocation package
    Flexible hours
    Weekday work

    Rethink recruit

    San Francisco, CA
    5 days ago
  • Slope is looking for a Senior Recruiter to drive research and scientific recruiting. This role involves full-cycle recruiting, including building sourcing strategies and collaborating with hiring managers across bioengineering, neuroscience, and machine learning. The ideal... 
    Senior
    Scientific

    Merge Labs

    San Francisco, CA
    5 days ago
  • $150k - $200k

     ...–$200,000 annually \n Employment: Full-Time, Permanent \n \n We are seeking an experienced Principal Scientist to provide scientific leadership across histopathology, translational biomarker, digital pathology, and tissue-based research programs. This is an excellent... 
    Senior
    Scientific
    Permanent employment
    Full time

    KA Recruiting Inc.

    San Francisco, CA
    25 days ago
  • $170k - $182.5k

    Syneos Health in San Francisco is seeking an experienced Medical Science Liaison to provide compliant scientific information to Key Contacts and collaborate with medical and scientific leaders. The role requires an advanced scientific degree and 2+ years of MSL experience... 
    Senior
    Scientific

    Syneos Health, Inc.

    San Francisco, CA
    1 day ago
  •  ...developing technology on the frontier of engineering and biology. Our first product is a...  ...About you We are looking for a senior R&D scientist/engineer who is excited to develop...  ...multidisciplinary approach, working with the mechanical, electrical, and software teams to... 
    Senior
    Work experience placement

    Current Surgical

    San Francisco, CA
    4 days ago
  •  ...Environmental Consultants is seeking a Lead, Senior, or Principal Biologist with experience...  ...the preparation and presentation of scientific and regulatory findings, contributing to...  ...Experience of working with scientists, planners, engineers, contractors, and agency specialists.... 
    Senior
    Scientific
    Full time
    For contractors
    For subcontractor
    Work at office
    Local area
    Remote work

    SWCA

    San Francisco, CA
    3 days ago
  •  ...Senior Consultant At Capgemini Invent, we believe difference drives change. As inventive transformation consultants, we blend our strategic, creative and scientific capabilities, collaborating closely with clients to deliver cutting-edge solutions. Join us to drive... 
    Senior
    Scientific

    Capgemini

    San Francisco, CA
    3 days ago
  • $232k - $252k

    Partner with product, engineering, and User Experience (UX) to develop data-driven product strategies.Translate ambiguous questions into...  .... We use our technologies for widespread public benefit and scientific discovery, ensuring safety and ethics are always our highest... 
    Senior
    Scientific

    Google

    San Francisco, CA
    3 days ago
  • $104.95k - $178.67k

     ...with Syska Hennessy Group. As a global leader in consulting, engineering, and commissioning services, we specialize in MEP,...  ...vertical transportation, and commissioning. We are seeking a Senior Mechanical Engineer to join our team in San Francisco or Sacramento, CA... 
    Senior
    For contractors
    Work from home
    Flexible hours

    Syska Hennessy Group

    San Francisco, CA
    7 days ago
  • $110k - $160k

     ...our communities, and our planet. If this sparks your interest, you’re in the right place.DLR Group has an opening for a Senior Mechanical Engineer.Locations: San Francisco, CAPosition SummaryAs a Senior Mechanical Engineer, you will be responsible for leading design of... 
    Senior
    Work at office

    DLR Group

    San Francisco, CA
    3 days ago
  • Syneos Health Commercial Solutions is seeking a Medical Science Liaison in the San Francisco area to collaborate with medical and scientific leaders and provide objective, evidence-based information to Key Contacts. You will contribute cutting-edge clinical data to... 
    Senior
    Scientific

    Syneos Health Commercial Solutions

    San Francisco, CA
    2 days ago
  •  ..., under DRU guidance. Responsibilities include grant writing, experimental design, data interpretation, and preparing peer-reviewed manuscripts, with supervision of junior lab members. UCSF emphasizes collaboration and scientific rigor. #J-18808-Ljbffr UCSF Health, AG
    Senior
    Scientific

    UCSF Health, AG

    San Francisco, CA
    5 days ago
  • $121.65k - $194.3k

     ...Francisco, CA, United StatesDepartment: Mechanical EngineeringBusiness Unit: ANA United StatesWork...  ...company delivering sustainable design, engineering, and consultancy solutions for natural...  ...in California is seeking an experienced Senior Process Mechanical Design Engineer to... 
    Senior
    Full time
    Part time
    Work at office
    Local area

    Arcadis

    San Francisco, CA
    4 days ago
  •  ...Senior Research & Development Engineer - RDE Location: San Francisco (In-person) Who We Are Omen is miniaturizing lab-grade spectroscopy into...  ...viability of our spectroscopy techniques, we need an R&D Engineer to act as our primary explorer. You will... 
    Senior

    Omen AI

    San Francisco, CA
    5 days ago
  • Coherence Neuro is seeking a Senior Clinical Scientist to provide scientific leadership for First In Human and Early Feasibility trials in a fast-paced neurotech startup. You will design studies, interpret data, and communicate findings to multidisciplinary teams across... 
    Senior
    Scientific

    Opto Biosystems

    San Francisco, CA
    3 days ago
  •  ...immunology and drug discovery efforts within the Immunobiology Open Innovation Team. The role demands deep immunology expertise, scientific leadership, and the ability to evaluate external opportunities while shaping program strategy. You will collaborate with internal... 
    Senior
    Scientific

    Biogen

    San Francisco, CA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior R&D Mechanical Engineer - Scientific Instrumentation. Be the first to apply!