Staff Software Engineer (Python)
Jetbridge AI
Staff Software Engineer
Help build the software platform that enables scientists to design and engineer living systems the same way engineers build modern software.
This company is developing a synthetic biology platform that allows scientists to design, simulate, and debug genetic systems at scale. Their technology combines biology, software engineering, and advanced computation to accelerate the development of next-generation therapeutics.
The team is building tools that transform biological engineering into a true engineering discipline. They are now hiring a Staff Software Engineer to help architect the core platform used by scientists and researchers to design complex biological systems.
The Role
You will play a key role in designing and evolving a platform used by bioengineers to design, search, and analyze genetic constructs. This is a highly technical role with significant architectural ownership.
You will collaborate closely with synthetic biologists, computational scientists, and product teams to build systems that model complex biological data and workflows.
The platform handles highly structured scientific data and requires thoughtful API design, scalable architecture, and robust backend systems.
What You'll Do
- Design and implement backend architecture that will shape the platform for years
- Build GraphQL APIs for querying and analyzing genetic construct data
- Develop services using Python, SQLAlchemy, and modern backend frameworks
- Architect complex data models representing biological systems
- Collaborate directly with scientists to understand workflows and translate them into software tools
- Design systems that scale as usage and data volume grow significantly
- Participate in on-call rotation and support production systems
What They're Looking For
- 10+ years building production-grade software systems
- Deep expertise in Python
- Experience designing APIs (GraphQL preferred)
- Strong experience designing scalable backend architectures
- Experience modeling complex data systems and relational databases
- Ability to make long-term architectural decisions
- Comfort working in highly ambiguous, first-of-its-kind product environments
- Strong collaboration skills across technical and scientific teams
Nice to have:
- Experience with GraphQL frameworks such as Strawberry
- Experience with SQLAlchemy or similar ORM tools
- Experience working with scientific, research, or highly complex datasets
Why This Role Stands Out
- Work on software that accelerates next-generation therapeutics
- Architect a platform used by scientists designing living systems
- High ownership and influence over system architecture
- Deep technical challenges involving complex biological data models
- Work at the intersection of biology, software engineering, and AI-driven research
If you enjoy designing systems from first principles and want your work to influence the future of biotechnology, this is a rare opportunity.
- ...Staff Software Engineer The typical day will include attending Agile standups, designing components or services, writing lots of code, testing... ...all of the following: JavaScript, TypeScript, React, Node, Python, Flask, end to end and unit testing frameworks. Cloud &...Suggested
- Position Staff Software Engineer- Python Location Boston, MA Job Id 1085 Number of Openings 1 Job Title Staff Software Engineer Essential Functions The typical day will include attending Agile standups, designing components or services, writing lots of code, testing...SuggestedContract work
$50 - $75 per hour
...code, and providing impactful feedback. Candidates should have strong programming skills in languages such as Kotlin, JavaScript, or Python, along with excellent writing abilities. This opportunity offers competitive pay starting at $50-75/hr based on performance and...SuggestedRemote workFlexible hours- ...biology platform--from cells to software--to enable the design and... ...therapeutics. What would software engineering be like without an IDE? How... ...code. We're looking for a Staff Software Engineer to help us... ...of genetic constructs using Python 3, SQLAlchemy and Strawberry....Suggested
$170k - $230k
...Staff Software Engineer Tutor Intelligence is building the technology and processes to let robots go where they've never gone before: the... .... Nice to haves (zero or more): Experience with Python, TypeScript, Go, or similar languages. Experience with ML...Suggested$200k - $325k
...Staff Software Engineer Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to... ...workloads in production Strong across the backend stack (Python, SQL, cloud infrastructure) and can pick up new tools and systems...- ...Staff Software Engineer – AI & MCP Assume a technical leadership role on the team, with ownership of solutions, systems, and projects. Develop... ...Advanced Backend & AI Services: Develop resilient Java and Python microservices, including building Model Context Protocol (...
- ...practices and frameworks among Machine Learning Engineers (MLEs)across the company.... ...Skills: Strong programming skills in C++ and Python Proven experience in GPU programming and... ...position may also involve working with software and technologies subject to U.S. export...
$155k - $180k
...discovery of life-saving treatments. Role Description The Staff Software Engineer will work cross functionally with the Computational Biology... ...the .NET ecosystem (Blazor, WPF, ADO.NET, MS SQL Server). Python and R experience are a plus. ~ Experience designing...$140k - $190k
...Staff Software Engineer Waltham, MA Xometry (NASDAQ: XMTR) powers the industries of today and tomorrow by connecting the people with big... ...full-stack development, including: - Backend development with Python (services, APIs, data-driven systems). - Backend...- ...Staff Software Engineer India About Starburst Starburst is the data platform for analytics, applications, and AI, unifying data across... ...: writing clean, testable, well-reviewed code in Java, Python, or Scala Experience building and optimizing data pipelines...Local areaFlexible hours
$146.6k - $215.1k
...system-level risk Develop and standardize software interfaces and tooling that interact... ...validation initiatives and influence engineering teams to adopt shift-left validation and... ...systems ~ Advanced programming expertise (Python preferred) with strong object-oriented...Work at officeShift work$242k - $333k
...The Perception Sensing team is looking for a Senior or Staff Software Engineer to drive the evaluation and architectural design of our PCP stack... ...and adverse weather. Qualifications Strong C++ and Python for running and modifying PCP metrics pipelines, automated...Odd jobTemporary workRelocation package$140k - $210k
...who we are. About this team Super.com engineering has four full-stack product development... ...We are looking to bring on a full-stack Staff Software Engineer for our Super+ vertical. This... ...the art architecture powered by Node and Python microservices and React frontend We use...Work experience placementRemote workFlexible hours$405k
...growing group of committed researchers, engineers, policy experts, and business leaders... ...Anthropic is seeking an exceptional Senior Staff Software Engineer to join the Claude Developer... ...audiences. Technical Stack Languages: Python, TypeScript Frameworks: FastAPI, React...Work at officeVisa sponsorshipFlexible hours- ...Hybrid Full-time, Staff Software Engineer at Activ Surgical About the job, About the Company Activ Surgical is an early-stage medical... .... · Proficiency in scripting languages, such as Python, or PowerShell script and Windows batch commands. · Proficiency...Full timeImmediate startFlexible hours
$10k
...Are you a Fullstack Engineer looking to make a big impact at a mission-driven company? Do... ...shipping, and maintaining complex full-stack software at scale Fluency in at least one backend... ...language, with a willingness to learn Python and JavaScript Experience working in a...Temporary workWork at officeRemote work$161k - $221k
...customers’ trust. The Defensive Cyber Engineering organization is responsible for the Security... ...’s Public Sector roadmap by hiring a Staff Software Engineer in the DC area. You’ll work... ...infrastructure and data pipelines. Experience with Python is required; proficiency in other...Permanent employmentFull timeWork at officeLocal areaRemote workFlexible hours$220k - $275k
...passionate about creating transformative change in healthcare. Staff Software Engineer The Role As a Staff Software Engineer, you will shape... ...systems environment. Your work will span: Backend: Python, Go, Java; microservices; REST and GraphQL Frontend:...$150k - $169k
...secure access to sensitive systems, and the engineers who build those products need to... ...are one of those engineers. As a Senior Staff Software Engineer, you will lead large-scale technical... ...systems. Backend Strong proficiency in Python, TypeScript, Go, or similar languages....Remote work$148k - $249k
...frameworks). - Build automation and observability tooling (Go/Python/Java, Kubernetes/Docker) for CI/CD-based performance... ...to stakeholders and leadership. Qualifications: - 5+ years software engineering or systems/performance engineering experience (BS in CS/EE or...Full timeWork at officeWork from homeFlexible hours$224k - $280k
...great therapists with the first software-enabled national network of... ...for the better. About engineering at Headway Building a new mental... ...mistakes. Tools we use: Languages: Python 3, TypeScript Libraries &... ...growth of those around them For staff engineers: Has designed and...Work from homeFlexible hoursShift work$140k - $210k
...Total Visits, March 2025) Day to Day We are looking for a Staff Software Engineer to design and build the AI Agentic core and foundation... ...architecture that integrates AI Agents orchestrated with LangGraph in Python, a scalable GraphQL API layer, and a responsive React...Temporary workWork experience placementLocal area- ...Staff Full-Stack Software Engineer Financial institutions - banks and credit unions - have begun a seismic shift in how they operate and... ...Stack & Tools React.js Node.js , TypeScript, Python GraphQL, REST, Websockets PostgreSQL, BigQuery,...Remote workWork from homeShift work
- ...Speridian Technologies is recruiting for a Staff Software Engineer - Full Stack for our State of California Client, the Department of Healthcare... ...framework | .NET Core, Blazor Experience with Java, Python, Go, or TypeScript/JavaScript is a plus Data & Messaging PostgreSQL...Full timeRemote workMonday to Friday
$160.2k - $246.3k
...simulation tests used for autonomous vehicle software validation. Lead cross-functional initiatives with Autonomy, Systems Engineering, Simulation, and Data teams to tightly... ...frameworks. ~ Proficient in developing Python for production systems, including unit testing...Local areaRemote workWork from homeRelocationRelocation packageFlexible hours$134k - $235.9k
...partners Behaviors, Perception, and Safety Engineers. The specific duties may include ML/... ...of an ML team and contribute strong software engineering (SWE) expertise. Support... ...Strong programming skills in modern C++ or Python Bonus: Experience with profiling...Local areaRemote workWork from homeRelocationRelocation packageFlexible hoursShift work$160.2k - $290.7k
...platform team develops the first layers of software on the GM Autonomous Vehicles from... ...vehicle platforms. Role As a Staff Software Engineers, you are the expert professionals identifying... ...~ Proficiencywith C++11 or later and Python ~ Proficiencyin debugging and...Work experience placementLocal areaRemote workWork from homeRelocation packageFlexible hours$242k - $290k
...Machine Learning Engineer The Perception Object Detection and Tracking team at Zoox deals with perception of all people and objects... ...in Computer Science or a related degree Fluency in C++ and Python, and CUDA code Experience delivering ML model integration in...- ...future. DataRobot's Fleet team is the engine behind how our platform runs across all... .... That's where you come in. As a Staff Software Engineer, you'll be responsible for technical... ...in modern programming languages such as Python or Go. Experience building production-...Local areaWorldwideFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Staff Software Engineer (Python). Be the first to apply!
- python engineer Boston, MA
- python developer Boston, MA
- python programmer Boston, MA
- full stack / python developer (remote) Boston, MA
- python developer data analytics Boston, MA
- backend python developer Boston, MA
- python developer remote Boston, MA
- senior python developer Boston, MA
- software product owner Boston, MA
- id software Boston, MA

