Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Scientist Process Modeling

$130k - $155k

MonoSol

Chicago Innovation Center | In office CIC Employees Chicago, IL 60607, USA Travel Required : Yes Description We're looking for an experienced process scientist or engineer with a strong foundation in first-principles modeling and chemical engineering to accelerate how we scale products and evaluate process changes across R&D and manufacturing. You will build and validate mechanistic and hybrid models that capture the physics of our materials and processes enabling faster, smarter decisions from pilot through full-scale production. This role sits at the intersection of engineering fundamentals, computational modeling, and real-world manufacturing impact. As a senior individual contributor, you'll lead the development of process models that simulate, predict, and de-risk scale-up, reducing our reliance on trial-and-error and compressing the time from formulation to production. You'll work closely with process engineers, R&D scientists, and our data science team to connect physics-based understanding with data-driven approaches, building toward hybrid models and digital twins that can be deployed across our manufacturing network. We're building new capabilities and we want people who are energized by that. Beyond building models, you'll help define how process modeling is practiced across the organization by establishing scalable methodologies, reusable simulation frameworks, and best practices that raise the bar for how we design, optimize, and transfer processes. This is an opportunity to do technically deep, high-impact work while shaping how modeling and simulation are applied in a materials and manufacturing environment. Key Responsibilities Process Modeling & Simulation Develop and validate first-principles and mechanistic models for key unit operations and process systems, capturing the physics of heat transfer, mass transfer, fluid dynamics, and reaction/dissolution kinetics relevant to our materials and processes. Build process flowsheet models using tools like Aspen Plus to simulate end-to-end process behavior and evaluate the impact of process changes, new formulations, and equipment configurations. Scale-Up & Process Transfer Lead modeling efforts that bridge pilot-scale experiments to manufacturing-scale operations by identifying scale-dependent risks, informing equipment selection, and defining operating windows. Develop scale-up and scale-down frameworks that reduce experimental cycles and accelerate the path from product development to production readiness. Work with the Engineering Technology Center to test and adopt your models into process R&D. Hybrid Modeling & Digital Twin Development Partner with the data science team to integrate first-principles models with data-driven approaches, building hybrid models that combine physical understanding with empirical learning. Contribute to the development and evolution of digital twins for critical process systems, supporting prediction, optimization, and what-if scenario analysis across the manufacturing network. Translate complex simulation outputs into clear, actionable engineering recommendations that inform R&D direction, process design, and manufacturing decisions. Develop compelling visualizations and technical narratives that enable cross-functional teams, from scientists to plant leadership, to quickly understand and act on modeling insights. Methodology, Standards & Capability Building Establish scalable modeling methodologies and reusable simulation workflows that can be applied across products, processes, and manufacturing lines. Act as a technical resource on process modeling best practices by mentoring team members, guiding analytical approaches, and elevating how modeling is used to support decision-making across the organization. Stay current with emerging tools, methods, and computational approaches in process simulation, multiscale modeling, and hybrid/digital twin frameworks. Qualifications Education Bachelor's degree in Chemical Engineering, Mechanical Engineering, Materials Science, Polymer Science, Physics, or a related technical field; Master's or PhD strongly preferred Experience 5+ years applying process modeling, simulation, or computational engineering to real-world problems in materials, chemicals, polymers, or related manufacturing environments Track record of building mechanistic or first-principles models that informed scale-up decisions, process design, or operational improvements — from model development through validation and deployment Experience bridging pilot-scale and manufacturing-scale operations, with a practical understanding of how process physics changes across scales Technical Skills Strong proficiency in process simulation tools such as Aspen Plus, Aspen HYSYS, gPROMS, or equivalent flowsheet modeling platforms Solid foundation in transport phenomena, thermodynamics, reaction/dissolution kinetics, and fluid dynamics as applied to process modeling Experience with CFD or finite element analysis tools (e.g., ANSYS Fluent, COMSOL Multiphysics, Star-CCM+) for unit operation or equipment-level modeling Proficiency in Python for custom model development, data analysis, and automation of simulation workflows Experience developing or contributing to hybrid models that integrate physics-based and data-driven approaches (preferred) Familiarity with digital twin concepts, reduced-order modeling, or model deployment in operational environments (preferred) Familiarity with statistical methods, design of experiments (DOE), and uncertainty quantification as applied to model validation and process characterization (preferred) Experience with version control (Git) and reproducible computational workflows Who you are Strong communicator who can translate complex simulation results into clear engineering recommendations for scientists, process engineers, manufacturing teams, and leadership Comfortable operating in ambiguous, cross-functional environments and taking ownership of high-impact problems without waiting for direction Self-directed senior IC who leads through technical credibility by shaping modeling approaches, driving alignment across teams, and raising the bar for how process knowledge is captured and reused Energized by continuous learning and staying at the forefront of process modeling, simulation, and computational engineering Additional information Applicable only to applicants applying to a position in any location with a pay disclosure requirements under state or local law: The compensation range that is described below is the possible base pay compensation that the company believes in good faith that it will pay for this role at the time of posting based on job grade for the position. Individual compensation within this range is based on many factors such as years of experience etc. so the company might pay more or less than the posted range and it is understood that this range may be modified in the future. In addition to base compensation, MonoSol provides a yearly incentive compensation bonus, a profit sharing bonus when eligible, a comprehensive benefits package including medical, dental, vision insurances, short term disability, long term disability, accidental death and dismemberment, term life insurance, voluntary term life insurance, transit flexible spending account (if applicable), employee assistance program, identity theft protection, 401k and paid time off (vacation and sick days) Compensation range - $130,000.00 - $155,000.00 Paid time off amount – 15 days

CLOSING

The above statements are intended to describe the general nature and level of the work being performed by employees assigned to this position. This is not intended as an exhaustive list of all responsibilities, duties, and skills required. MonoSol, LLC reserves the right to make changes to the job description whenever necessary. Disclaimer As part of MonoSol, LLC's employment process, finalist candidates will be required to complete a drug test and background check prior to employment commencing. MonoSol, LLC is an equal opportunity employer. All qualified applicants will be considered without regard to race, national origin, gender, age, disability, sexual orientation, veteran status, or marital status. Travel Required Yes . Occasional visits to our manufacturing facilities and innovation center Equal Opportunity Employer This employer is required to notify all applicants of their rights pursuant to federal employment laws.For further information, please review the Know Your Rights notice from the Department of Labor. #J-18808-Ljbffr MonoSol

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Senior Scientist Process Modeling in Brooklyn, NY vacancy
  • Join the Clean Energy Revolution Become a Modeling, Forecasting, and Economic Analysis, Senior Advisor at Southern California Edison (SCE) and build a better...  ...methodologies, and strengthening business processes. Your work will support data-driven decision-making... 
    Senior
    Contract work
    Remote work
    Relocation

    Southern California Edison

    Brooklyn, NY
    1 day ago
  • The Bill & Melinda Gates Foundation invites applications for a Senior Research Scientist in Seattle, WA. The two-year limited-term role focuses on population health modeling, nutrition science, and disease research, requiring a PhD in a quantitative field and a minimum... 
    Senior

    OpenDoorHub

    Brooklyn, NY
    5 days ago
  • Radiance Technologies, Inc. is seeking a Senior Research Scientist to advance data processing techniques for EO, IR, and SAR data at Wright-Patt AFB, OH. Responsibilities include developing algorithms for detection and tracking, R&D for performance enhancement, and collaborating... 
    Senior

    Radiance Technologies, Inc.

    Brooklyn, NY
    4 days ago
  •  ...a seasoned Staff Computational Biologist to advance genomics modeling and signature discovery, applying statistics to build new cancer...  ...US, based out of the Brisbane, California campus, collaborating with ML scientists and wet-lab partners. #J-18808-Ljbffr Neura Market
    Senior
    Remote work

    Neura Market

    Brooklyn, NY
    5 days ago
  •  ...supervision, you will design and conduct analyses, develop data collection systems, and model processes to identify cost savings and performance gains. You will work with managers and senior staff to define objectives, build data-driven recommendations, and oversee analysts... 
    Senior

    Alsip-Merrionette Park Public Library District

    Brooklyn, NY
    1 day ago
  • $167.1k - $226.1k

     ...alongside talented engineers, scientists, and product leaders in a...  ...scientists, and collaborate with senior leadership to shape the...  ...generative AI and large language models Develop and deploy innovative...  ...personalization to natural language processing, computer vision, recommender... 
    Senior
    Local area
    Flexible hours

    Amazon

    Brooklyn, NY
    14 hours ago
  •  ...patients while transforming your career. Senior Scientist - Functional Genomics What you will do...  ...), in both in vitro and in vivo model systems. Design and execute innovative...  ...participate in the job application or interview process, to perform essential job functions,... 
    Senior
    Flexible hours

    Amgen SA

    Brooklyn, NY
    4 days ago
  • $129.6k - $219.6k

     ...general intelligence (AGI) with a focus in natural language processing at the senior and principal levels to join our AI Lab in Seattle, Beijing...  ...and thought leaders in generative AI, large language models, reinforcement learning, multimodal reasoning and generation... 
    Senior
    Relocation package

    Web3 Pulse

    Brooklyn, NY
    5 days ago
  • $109.05k - $149.94k

     ...associated intellectual property with patent attorneys Collaborate with process research and innovation teams Coordinate with and/or direct...  ...and property relationships for new product inventions Utilize modeling and characterization tools with colleagues within Inorganic... 
    Senior
    Full time
    Work experience placement

    Corning Incorporated

    Brooklyn, NY
    4 days ago
  • $156.4k - $190k

    About the Senior Product Scientist at Headspace: We are seeking a Senior Product Scientist to own and...  ...to write SQL and Python, contribute to model evaluation, and be a proficient...  ...range for your location during the hiring process. At Headspace, base salary is but one... 
    Senior
    Full time
    Work at office
    Local area
    Remote work
    3 days per week

    Neura Market

    Brooklyn, NY
    5 days ago
  • $173k

     ...and build for travelers everywhere. Senior Machine Learning Scientist The Senior Machine Learning Scientist...  ...framing and data preparation through model/agent design, orchestration, deployment...  ...during the application or recruiting process, please submit a request at About... 
    Senior
    Worldwide

    Expedia, Inc.

    Brooklyn, NY
    4 days ago
  • Southern California Edison is seeking a Modeling, Forecasting, and Economic Analysis, Senior Advisor to advance the energy efficiency portfolio within the...  ...enhance forecasting methodologies, and improve business processes to support data-driven decision-making and... 
    Senior

    Southern California Edison

    Brooklyn, NY
    1 day ago
  •  ...patients while transforming your career. Senior Scientist What you will do Lets do this. Lets...  ...drug product formulation and fill/finish process development for various biological...  ...including generative AI, large language models (LLMs), and in silico modeling, to drive... 
    Senior
    Worldwide
    Flexible hours

    Amgen SA

    Brooklyn, NY
    5 days ago
  • $138.8k - $232.7k

     ...do... Own 3D statistical variation analysis in 3DCS end to end — model build, results correlation, issue resolution, and the...  ...vehicle. Architect body build sequences with dimensional accuracy, process variation, and manufacturing feasibility front of mind. Solve problems... 
    Senior
    Work at office
    Immediate start
    Visa sponsorship
    Flexible hours

    Ford

    Brooklyn, NY
    5 days ago
  •  ...Opportunity Stantec is currently seeking to add a Senior Hydrogeologist to our team in a client-...  ...data, site assessments, conceptual site models, progress reports, site investigation...  ...committed to ensuring our recruitment process is accessible to all. If you require reasonable... 
    Senior
    Full time
    Temporary work
    Part time
    Work at office
    Local area
    Remote work
    Worldwide
    Flexible hours

    Stantec Consulting International Ltd.

    Brooklyn, NY
    3 days ago
  • $100k - $140k

     ...sustainable future.    Position Overview: As a transport modeling physicist at Thea Energy, you will be an architect of our...  .... Strong understanding of gyrokinetic theory and transport processes Expertise in developing scientific simulation codes using Python... 

    Thea Energy

    Kearny, NJ
    a month ago
  • We are searching for the best talent for a Senior Scientist, Protein Analytical Development, Characterization located in Malvern, PA. Purpose...  ...assays in support of product characterization and process development of protein-based therapeutics. The successful candidate... 
    Senior

    Lehighbar

    Brooklyn, NY
    1 day ago
  •  ...Chalice (Chino, NM) to lead geological exploration and resource modeling efforts. You will log drill samples, create and update...  ...diverse data types, and collaborate with metallurgists to support processing testing. The role requires a geology degree with experience, strong... 
    For contractors

    Society of Exploration Geophysicists

    Brooklyn, NY
    2 days ago
  • $90k - $110k

    ## Senior ScientistApplyremote type: On - Sitelocations: USA-St Paultime type: Full timeposted...  ...end markets. Learn more at ## Senior Scientist### Position OverviewH.B. Fuller is seeking...  ...* Lead R&D projects using Stage-Gate processes and project management principles.*... 
    Senior
    Work experience placement

    H.B. Fuller Company

    Brooklyn, NY
    4 days ago
  • $95k

     ...complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process. Senior Scientist Full Time Professional Albany, NY, US 7 days ago Requisition ID: 1113 Salary: $95,000.00 Annually Position Summary:... 
    Senior
    Full time
    Work at office
    Monday to Friday

    Acphs

    Brooklyn, NY
    3 days ago
  • $81.9k - $135.1k

     ...Services Organization (FSO). Our focused model and bold ambition have put us at the center...  ...U.S. and global clients, leveraging deep process and service delivery expertise that sets...  ...for the asset management industry. As a senior analyst, you’ll collaborate with experienced... 
    Senior
    Summer holiday
    Local area
    Flexible hours

    EY

    Hoboken, NJ
    2 days ago
  • Amgen is seeking a Senior Scientist in Thousand Oaks, CA, to lead late-stage drug product formulation and fill/finish process development across biologics modalities. You will integrate data from multi-functional teams, stay ahead of industry trends, and drive innovation... 
    Senior

    Amgen SA

    Brooklyn, NY
    5 days ago
  • Radiance Technologies is looking for a Senior Research Scientist in Kentucky to advance data processing techniques for EO, IR, and SAR data. The role involves designing algorithms, performing research, and collaborating on Near Real Time systems. Requirements include proficiency... 
    Senior
    Remote work

    Radiance Technologies

    Brooklyn, NY
    5 days ago
  •  ...outside the division and identifying new methods of performing work. This requires the incumbent to demonstrate expert analytical and process analysis skills. Analyzes mission critical tax related program areas to discern trends in program delivery. Consolidates report... 
    Senior

    Treasury Department

    Brooklyn, NY
    3 days ago
  •  ...Tetra Tech is looking for a full-time, senior Health Physicist for our Albuquerque, NM...  ...analytics, and the expertise of world-class scientists and engineers to create meaningful...  ...using computer software including word processing, Minitab, ProUCL, spreadsheet, and database... 
    Senior
    Full time
    For contractors
    Work experience placement
    Work at office
    Local area
    Worldwide
    Monday to Friday
    Flexible hours
    Night shift

    Society of Exploration Geophysicists

    Brooklyn, NY
    1 day ago
  • Senior Scientist, Drug Discovery Biochemistry & Biophysics Redwood City, CA Senior Scientist, Drug Discovery Biochemistry & Biophysics About...  ...-kind discovery platform at the intersection of phenotypic models of aging, chemistry, and AI. Backed by top-tier VCs, and with... 
    Senior
    Visa sponsorship
    Shift work

    Integratedbio

    Brooklyn, NY
    4 days ago
  • Senior Research ScientistSkip to main content#Senior Research Scientist page is loaded## Senior Research ScientistApplylocations: Wright-Patt AFB, OH - NASICtime type...  ...who will continue advancement of data processing techniques and algorithms designed to exploit... 
    Senior
    Remote work

    Radiance Technologies, Inc.

    Brooklyn, NY
    1 day ago
  • $76.8k

     ...indirect tax compliance and advisory across multiple jurisdictions. You will collaborate with cross-functional teams to automate processes and implement AI-driven tax solutions. You will deliver accurate, timely tax reporting while driving continuous improvement across... 
    Senior
    Work at office
    Remote work

    Zoom Corporation

    Brooklyn, NY
    4 days ago
  • $98.4k - $147.6k

    ## Senior Scientist - BiophysicsApplylocations: US - California - San Diegotime type: Full timeposted on: Posted Todayjob requisition id:...  ...has experience working with DNA, and/or in the study of DNA-processing enzymes such as polymerases and helicases. Single-molecule biophysics... 
    Senior
    Local area

    Illumina

    Brooklyn, NY
    3 days ago
  • $145k - $161k

     ...Overview We are seeking an exceptionally driven, discovery-minded Senior Scientist to join our Platform Technology & Innovation team. This team...  ...technologies from in vitro systems into in vivo animal models, using non-viral (e.g., LNP) or viral (e.g., AAV) delivery systems... 
    Senior
    Full time
    Temporary work

    American Society of Gene & Cell Therapy

    Brooklyn, NY
    5 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Scientist Process Modeling. Be the first to apply!