VP, Human Resources

Kiniksa Pharmaceuticals is a commercial‑stage biopharmaceutical company developing and commercializing novel therapies for diseases with unmet need, with a focus on cardiovascular indications. With deep expertise in immunology and inflammation, Kiniksa is advancing a growing portfolio of approved and investigational medicines, anchored by its lead product, ARCALYST, the first and only FDA‑approved therapy for recurrent pericarditis. Grounded in rigorous science and bold innovation, the company fosters a highly collaborative, patient‑first culture led by accomplished life sciences leaders. At Kiniksa, talented individuals are trusted and empowered to make a real impact—shaping the future of medicine while improving the lives of patients who need it most.Reporting directly to the COO, the Vice President of Human Resources will be a driving force behind Kiniksa’s global HR vision. As a pivotal member of the HR Leadership Team, this executive will partner closely with senior leaders across the organization to shape and execute enterprise-wide initiatives that fuel innovation, strengthen organizational agility, and elevate a high‑performance culture.This leader will inspire and develop a team of HR Business Partners while collaborating seamlessly with HR Operations and Talent teams to deliver integrated, scalable people solutions that power Kiniksa’s continued growth and impact.This role is based in our Lexington office and requires an onsite presence five days per week to support our commitment to seamless partnership, timely decision-making, and high-impact execution.Responsibilities (including but not limited to):Lead the execution of a comprehensive HR strategy across the global organization, aligned with enterprise goals and cultureServe as a strategic partner to Kiniksa’s senior leadership, advising on organizational design, talent planning, and leadership developmentBuild and manage a high-performing HR Business Partner team to deliver coordinated support across functionsDrive organizational effectiveness through change management, performance enablement, and leadership capability buildingBuild strong, influential relationships with key stakeholders, removing barriers to enable operational transformation across the businessFacilitate regular leadership team meetings and drive continuous improvement in leadership capability and organizational effectivenessEstablish a continuous improvement strategy grounded in business priorities to ensure organizational readiness for future growth and expansion.Partner with Talent Acquisition to attract and retain top talent in a competitive, high-growth environmentOversee employee relations and performance management strategies to foster accountability, and fast action in recognition and performance outcomesCollaborate with HR Operations to ensure compensation and benefits programs are implemented in a way that supports talent retention and motivationChampion and reinforce a culture that is aligned with enterprise-wide values and the strategic priorities of KiniksaQualifications and Experience:15+ years of Human Resources experience including HR leadership and people management Bachelor’s degree in business, HR, or related field requiredExperience working with senior leadership, with an established track record of delivering resultsDemonstrated success in a fast faced, innovative biotech/life sciences companyDirect experience with executive and non-executive compensation, experience in incentive sales compensation a plusExecutive presence and ability to lead and influence by exampleFlexible to adjust priorities based on overall business needProven mindset of proactive continuous improvementStrong attention to detailStrong commitment to compliance and ethical standardsProficient with Microsoft Office suite (i.e., Word, PowerPoint, Excel, Outlook, SharePoint, etc.)Ability to travel up to 25%Salary is commensurate with experienceCompensation decisions are based on objective criteria including role responsibilities, experience/qualifications, internal equity, geographic location, and external market benchmarks.Pay Range$310,000—$345,000 USDKiniksa is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, transgender status, age, genetics, national origin, protected veteran status, or disability status, or any other legally protected category. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Kiniksa does not accept unsolicited resumes from staffing agencies or search firms. Any resumes submitted without a signed agreement will be considered property of Kiniksa, and no fees will be paid.