Post-Doctoral Research Fellow - Immunotherapy

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington. With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality. At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. The Markey Lab was established in October 2021 and is seeking to recruit a Post-Doctoral Research Fellow to join the team. The lab focuses on the intersection between the microbiome (and its metabolites) and post-transplant and/or post-immunotherapy immune function and clinical outcomes. In this role, the candidate will be involved in projects that take clinical observational findings from studies of the intestinal microbiome (e.g. Markey et al, Blood 2020; Miltiadous et al, Blood 2022; Ueland et al, Blood Advances 2026) through to mechanistic studies in mouse models. A number of observational studies have been performed supporting associations between the microbiome and transplant and/or immunotherapy outcome, but mechanistic data is currently lacking. Combining hypotheses generated from our clinical data with state-of-the-art immunology techniques in mouse model systems is important for addressing the current knowledge gaps in the field and supporting the design of microbiome-targeted interventions in future. This is a full-time lab-based position based on campus at the Fred Hutchinson Cancer Center in Seattle. This position is funded via a project grant that continues until 2028. Please submit a cover letter detailing interest in the position as well as names and contact details for three referees with your application. Responsibilities Projects are predominantly focused on mechanism using pre-clinical models, and are specifically focused on immune reconstitution, and chronic graft-versus-host disease. Experience with microbiology and computational aspects of microbiome analysis. Experience in analyzing single-cell transcriptomic data. Minimum Qualifications A recent PhD, MD/PhD, or MD in a relevant biological field. Candidate will ideally have laboratory experience in mouse models of human disease, flow cytometry and sequencing methods. Excellent written and verbal communications skills are essential. The annual base salary range for this position is from $80,172 to $95,014, and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance. Although Fred Hutch is not sponsoring most H-1B visas at this time, candidates who already hold an H-1B sponsored by another organization and are currently in the U.S. may be eligible for this position. #J-18808-Ljbffr Mundelein Elementary School District 75