Global Real Estate Program Manager

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. The Global Real Estate Program Manager is responsible for executing and managing real estate transactions across Illumina's global portfolio, including new leases, renewals, expansions, consolidations, subleases, and terminations. This role serves as a critical link between Global Real Estate, Finance, Legal, Facilities, and business unit stakeholders to ensure transactions and spaces are aligned with the company's strategic real estate plan and business objectives. Key Responsibilities Manage the full lifecycle of real estate transactions worldwide, including new site acquisitions, lease renewals, expansions, contractions, subleases, and terminations. Coordinate with external brokerage partners, legal counsel, and outsourced transaction management service providers to negotiate commercially favorable lease terms, and manage provider performance against agreed-upon KPIs. Track and manage all critical dates across the global portfolio, ensuring timely action on renewal options, termination rights, expansion rights, and other contractual obligations. Develop and maintain financial models to evaluate transaction alternatives, including NPV, DCF, total cost of occupancy, and P&L impact analyses. Prepare transaction approval packages, lease commitment schedules, expense and capital forecasts, and other financial reports for executive, capital committee, and Board of Directors review. Generate capacity and demand models to evaluate and forecast short- and long-term space needs across the global portfolio, and develop executive-level recommendations to address supply and demand gaps. Partner with Finance to ensure accurate treatment of lease transactions under ASC 842 and IFRS 16, including balance sheet impact assessment for new and modified leases. Monitor and manage sublease income and interface with the third-party lease administration provider to maintain a correct and timely monthly rent roll. Coordinate with Accounts Payable to ensure accurate rent, CAM, and operating expense payment schedules. Own and maintain the real estate database, ensuring all portfolio data is current, accurate, and audit-ready. Collaborate cross-functionally with Finance, Legal, EHS, Procurement, Facilities, and business unit leaders to ensure transaction requirements are clearly defined, stakeholder needs are met, and internal moves, reconfigurations, and space reallocations within existing facilities are effectively planned and executed. Support the development and maintenance of standardized global real estate transaction processes, playbooks, and governance frameworks. Contribute to the company's Strategic Real Estate Plan, including scenario planning for portfolio optimization, site consolidation, and growth scenarios. Qualifications and Experience Bachelor's degree in Business Administration, Real Estate, Finance, or a related field. Minimum of 5 years of progressive experience in corporate real estate transaction management, commercial real estate brokerage, or a related facilities discipline. Demonstrated experience managing a portfolio of lease transactions across multiple geographies. Strong financial modeling skills, including comfort with NPV, DCF, and lease-vs-own analyses. Familiarity of ASC 842 or IFRS 16 lease accounting standards. Experience with real estate management systems. Proficiency in Microsoft Excel, PowerPoint, and Word. Excellent organizational skills with the ability to manage multiple concurrent transactions and deadlines. Strong written and verbal communication skills, including experience preparing executive-level presentations and approval packages. The estimated base salary range for the Global Real Estate Program Manager role based in the United States of America is: $118,200 - $177,200. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off. We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact View email address on click.appcast.io. To learn more, visit: The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship. The potential of genomics to change the world is unparalleled. At Illumina, we are leading the way. Our technology empowers researchers and clinicians globally to improve cancer treatments, change the course of diseases, protect the environment, and fight food insecurity. We are made up of dedicated professionals, all-in on creating a better world – and we need every skill set on our path to making genomics useful for all. Learn more about life at Illumina. Illumina has been made aware of fraudulent schemes in which individuals falsely claim to represent Illumina, our Talent Acquisition team, or our Human Resources organization. Please note: • All legitimate Illumina career opportunities are posted on the Illumina Careers website. • Illumina will never ask candidates to pay fees, transfer money, purchase equipment, or provide banking information during the recruitment process. • Illumina does not extend employment offers without a formal interview process. • Official recruiting communications will come from authorized Illumina email addresses (View email address on click.appcast.io). If you are unsure whether a communication is legitimate, please contact us at [Talent Acquisition Contact Email] before sharing any personal information. Thank you for helping us protect the integrity of the hiring process and your experience.