Clinical Research Nurse II

Job Title: Clinical Research Nurse IIJob Description

We are seeking a dedicated Clinical Research Nurse II to join our Phase I Clinical Research Unit. This role requires a commitment to providing exceptional nursing support and ensuring the safety and confidentiality of study subjects. The ideal candidate will be comfortable working independently, particularly during overnight shifts, and will possess strong nursing skills to respond effectively to medical issues as they arise.

Responsibilities

• Provide general nursing support for a Phase I research unit.

• Monitor subjects overnight and respond appropriately to medical issues.

• Draw blood and start IVs as needed when research technicians are unavailable.

• Evaluate adverse events and manage safety reporting activities in a timely manner.

• Review study protocols and informed consent forms, identifying and communicating potential issues.

• Participate in nursing activities as required by protocol, ensuring compliance with SOPs and regulatory guidelines.

• Communicate with the Principal Investigator and study physicians to organize study-specific nursing activities.

• Participate in quality and compliance improvement initiatives, providing feedback as appropriate.

• Maintain accurate and complete source data, facilitating the resolution of discrepancies or issues.

• Facilitate training of new nursing personnel and report trainee progress to management.

• Participate independently in recruitment and screening activities to ensure appropriate enrollment of study subjects.

Essential Skills

• Registered Nurse with at least 1 year of experience in clinical trials.

• Familiarity with ICH, GCP, FDA, and pharmaceutical guidelines.

• Active Illinois RN license.

• Experience in ICU, telemetry, or emergency room settings.

• Proficient in starting IVs, computer usage, and assessment skills.

Additional Skills & Qualifications

• BSN degree preferred.

• Experience in adverse event/safety reporting is helpful.

• Comfortable working independently and reacting quickly to issues.

• Dependable and flexible with weekend coverage availability.

• Ability to hold another part-time or full-time position.

Work Environment

The position is based in a 57-bed Phase I Clinical Research Unit. The overnight environment is generally calm, with subjects sleeping from 11:00 PM to 5:00 AM. The staffing ratio is approximately 1 nurse to 57 subjects, and the nurse typically works independently. The position is an overnight role with hours ranging from 0-40 hours per week, depending on the needs of the unit. The typical schedule involves 16-24 hours per week with a strong preference for every other weekend availability. Shift options include an 8-hour shift starting at 6:45 PM or a 12-hour shift starting at 10:45 PM. Major holidays have no work available, but other holidays may require coverage if subjects are present.

Job Type & Location

This is a Contract position based out of Grayslake, IL.

Pay and Benefits

The pay range for this position is $40.00 - $53.00/hr.

Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: Medical, dental & vision Critical Illness, Accident, and Hospital 401(k) Retirement Plan Pre-tax and Roth post-tax contributions available Life Insurance (Voluntary Life & AD&D for the employee and dependents) Short and long-term disability Health Spending Account (HSA) Transportation benefits Employee Assistance Program Time Off/Leave (PTO, Vacation or Sick Leave)

Job Type & Location

This is a Contract position based out of Grayslake, IL.

Application Deadline

This position is anticipated to close on Oct 16, 2026.

Workplace Type

This is a fully onsite position in Grayslake,IL.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email View email address on click.appcast.io for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.