Clinical Program Manager - Global Study Lead

Akero Therapeutics seeks a Clinical Program Manager to serve as Global Study Lead for a large Phase 3 clinical study of efruxifermin for metabolic disease. The role requires end-to-end operational oversight from initiation through closeout, managing CRO partnerships, cross-functional coordination, and stakeholder reporting.

Responsibilities

• Serve as primary Clinical Operations contact and Global Study Lead for Phase 3 trial
• Direct study planning, enrollment strategy, site management, and ongoing conduct
• Oversee CRO performance, priorities, timelines, deliverables, and quality standards
• Identify, mitigate, and resolve operational risks and cross-functional issues
• Develop and manage study timelines, enrollment projections, budgets, and metrics

Requirements

• Experience as Clinical Program Manager or Global Study Lead for Phase 3 studies
• Demonstrated expertise in clinical operations planning, execution, and study oversight
• Proven ability to manage CRO relationships and external vendor partnerships
• Strong cross-functional collaboration skills with internal and external stakeholders
• Experience with study metrics, timelines, budgets, and operational planning
• Knowledge of clinical compliance, audit readiness, and regulatory requirements
• Experience working within clinical, regulatory, and quality functions