Mechanical Engineer
$100k - $210kYoh, A Day & Zimmermann Company
Get AI-powered advice on this job and more exclusive features. Direct message the job poster from Yoh, A Day & Zimmermann Company Principal Scientific Recruiter at Yoh, A Day & Zimmermann Company Yoh Life Sciences is hiring a Staff Mechanical Engineer for a growing cell and gene therapy customer in South San Francisco. As a Staff Mechanical Engineer, you will take ownership of a wide range of tasks pertaining to high-value internal projects - from requirements capture to novel concept research & development, to CAD design and component selection, to bring-up and testing of finished assemblies. This is a multidisciplinary role & this individual will interface with scientists, researchers, and engineers to develop the best solutions possible. The successful candidate will be a resident expert in the areas of mechanical design, fluidic control, and highly automated instrument development. Industry: Cell and Gene Therapy Location: South San Francisco Pay: $100,000 - 210,000 DOE Schedule: M - F 9-5 Type: Permanent Responsibilities Responsible for the design, development, and prototyping of mechanical components and consumables used in mechanical sub-systems & complex biotech instruments Design and development of automated test fixtures to validate the reliability and robustness of novel components Interface with systems & mechanical engineering teams to negotiate designs that meet product requirements & are feasible to manufacture economically Conduct design reviews and present fresh ideas, new technologies, and creative solutions to design problems Define subsystem architecture Show proof of concept through rapid prototyping Ability to extract design requirements from a broad spectrum of user needs Identify potential design risks and provide a path to derisk/pivot rapidly Work closely with the scientific team through the creation of verification /validation protocols (IQ, OQ, PQ) and successful execution, data generation, report and documentation Create comprehensive work instructions and manufacturing SOPs as needed for finished designs Requirements BS or MS in Mechanical Engineering, Mechatronics Engineering, or equivalent experience 12+ years of extensive, hands-on experience in biotech automation, semiconductor, or similarindustries Excellent verbal, written, presentation, and interpersonal skills Strong analytical and problem-solving skills Prior experience with FDA regulations and ISO, cGMP, and QMS standards is a plus Knowledge and/or hands-on experience with machine shop tools a plus Knowledge of GD&T, as well as strong proficiency with SolidWorks Creative, self-motivated, and flexible to work in a small company environment and assume a wide variety of tasks Work history with several successful iterations of highly automated instrument design and development (biotech industry experience preferred) Desire to be part of a rapidly evolving organization with compelling technology and take products and processes to the next level Experience with Python, or high-level scripting software languages, a plus Self-awareness, integrity, authenticity, and a growth mindset Estimated Min Rate : $100000.00 Estimated Max Rate : $210000.00 Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply. Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. Visit to contact us if you are an individual with a disability and require accommodation in the application process. For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Seniority level Seniority level Mid-Senior level Employment type Employment type Full-time Job function Referrals increase your chances of interviewing at Yoh, A Day & Zimmermann Company by 2x Get notified about new Mechanical Engineer jobs in South San Francisco, CA . Menlo Park, CA $139,000.00-$200,000.00 2 weeks ago Palo Alto, CA $110,000.00-$140,000.00 2 weeks ago Mechanical Engineer: Robotics Product Hardware Engineering Manufacturing Engineer, Manufacturing Development South San Francisco, CA $85,000.00-$100,000.00 1 month ago Union City, CA $90,000.00-$120,000.00 2 weeks ago San Francisco, CA $140,000.00-$270,000.00 5 months ago Alameda, CA $90,000.00-$120,000.00 2 weeks ago San Francisco, CA $150,000.00-$200,000.00 22 hours ago Mechanical Engineer — Intern (Fall 2025) We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI. #J-18808-Ljbffr Yoh, A Day & Zimmermann Company
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