Principal ML Ops Engineer
Pragmatike
Location: Cambridge, MA (Eastern Time / UTC -4). Relocation package available or Remote option for Out-Of-State applicants. Start date: ASAP. Languages: English (required). About The Role Pragmatike is hiring on behalf of a fast-growing AI startup recognized as a Top 10 GenAI company by GTM Capital, founded by MIT CSAIL researchers. We are seeking a Staff / Principal ML Ops Engineer to lead the design, implementation, and scaling of the company’s ML infrastructure and production AI systems. This is a high-impact, architecture-defining role where you’ll work across the entire model lifecycle—training, evaluation, deployment, observability, and continuous optimization. You will partner closely with AI researchers, GPU systems engineers, backend teams, and product stakeholders to ensure the company’s large‑scale AI systems are robust, efficient, automated, and production‑grade. This role is ideal for someone who has already built and owned ML platforms at scale and can drive strategy as well as hands‑on execution. What You’ll Do Architect, build, and scale the end‑to‑end ML Ops pipeline, including training, fine‑tuning, evaluation, rollout, and monitoring. Design reliable infrastructure for model deployment, versioning, reproducibility, and orchestration across cloud and on‑prem GPU clusters. Optimize compute usage across distributed systems (Kubernetes, autoscaling, caching, GPU allocation, checkpointing workflows). Lead the implementation of observability for ML systems (monitor drift, performance, throughput, reliability, cost). Build automated workflows for dataset curation, labeling, feature pipelines, evaluation, and CI/CD for ML models. Collaborate with researchers to productionize models and accelerate training/inference pipelines. Establish ML Ops best practices, internal standards, and cross‑team tooling. Mentor engineers and influence architectural direction across the entire AI platform. What Are Looking For Deep hands‑on experience designing and operating production ML systems at scale (Staff/Principal‑level expected). Strong background in ML Ops, distributed systems, and cloud infrastructure (AWS, GCP, or Azure). Proficiency with Python and familiarity with TypeScript or Go for platform integration. Expertise in ML frameworks: PyTorch, Transformers, vLLM, Llama‑factory, Megatron‑LM, CUDA / GPU acceleration (practical understanding). Strong experience with containerization and orchestration (Docker, Kubernetes, Helm, autoscaling). Deep understanding of ML lifecycle workflows: training, fine‑tuning, evaluation, inference, model registries. Ability to lead technical strategy, collaborate cross‑functionally, and operate in fast‑paced environments. Bonus Points Experience deploying and operating LLMs and generative models in production at enterprise scale. Familiarity with DevOps, CI/CD, automated deployment pipelines, and infrastructure‑as‑code. Experience optimizing GPU clusters, scheduling, and distributed training frameworks. Prior startup experience or comfort operating with ambiguity and high ownership. Experience working with data engineering, feature pipelines, or real‑time ML systems. Why This Role Will Pivot Your Career Research pedigree: MIT CSAIL founders recognized for breakthrough AI and systems contributions. Customer impact: Deploy AI solutions powering Fortune 500 clients. Industry momentum: Lab alumni have led high‑value acquisitions (MosaicML, Databricks, Run:AI, Nvidia, W&B, CoreWeave). Funding & growth: Oversubscribed seed round, next funding in 2026. Career growth & influence: Lead AI initiatives, optimize pipelines, and directly impact production AI systems at scale. Culture & autonomy: Own critical systems while collaborating with world‑class engineers. Aspirational impact: Solve AI performance challenges few engineers ever face. Benefits Competitive salary & equity options Sign‑on bonus Health, Dental, and Vision 401k Pragmatike is an Equal Opportunity Employer and is committed to providing equal employment opportunities to all applicants without discrimination. We recruit on behalf of our clients and prohibit discrimination and harassment based on race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, termination, layoff, recall, transfer, leaves of absence, compensation, and training. We are committed to a fair and inclusive hiring process. We process your personal data solely for recruitment purposes, in accordance with applicable privacy laws, and maintain reasonable safeguards to protect your information. Your data may be shared with our client(s) for hiring consideration, but will not be disclosed to third parties outside of the recruitment process. #J-18808-Ljbffr Pragmatike
$142k - $203k
Early Warning Services LLC is seeking a Senior ML Ops Engineer in San Francisco to enhance our machine learning operations. This role involves designing and maintaining scalable ML infrastructure and collaborating with data scientists and engineers. The ideal candidate...Suggested$200k
Skyrocket Ventures seeks a founding DevOps / Systems / ML Ops Engineer in San Francisco, CA. Hybrid work from home up to 2x/week with focus on AWS/Azure, Kubernetes, CI/CD, and video pipeline operations. Salary up to $200k plus equity, in a small, fast-growing physical...SuggestedWork from home$200k
Founding DevOps / Systems / ML Ops Engineer - Physical AI Startup Location: San Francisco, CA (you could work from home up to 2x/week) The company’s product involves physical AI, spatial intelligence, and multimodal LLMs. It is making real world infrastructure (like airplanes...SuggestedWork from home- TRM Labs, an AI-powered intelligence company, seeks a Senior or Staff ML Systems Engineer - LLM to scale AI infrastructure and production-grade ML tooling. You will build modular stacks, embed models into real-time workflows, and evaluate state-of-the-art AI tools to ensure...Suggested
- ...transformers and spatial models run efficiently on both cloud and edge compute resources. Learn more at About the Role As an ML / DevOps Engineer, you will play a pivotal role in advancing our infrastructure, scaling enterprise deployment workflows, and refining...SuggestedWork at office
- Ginas Tech Jobs is seeking a Principal Machine Learning Engineer to set the technical standard for ML systems across training, inference, evaluation and deployment. This 100% remote role balances hands‑on engineering with architectural leadership, spanning data, models...PrincipalRemote job
- About the Role We are seeking a Principal / Distinguished AI/ML Researcher and/or Engineer with deep experience in reasoning, planning, and decision-making systems . This role is ideal for individuals who have architected post-training intelligence frameworks, integrated...PrincipalLocal area
- ...casual encounter or long‑term relationship. We’re doubling down on ML as the future of Grindr, and in these early days, you’ll drive... ...Provide technical leadership across teams, collaborating with engineering, data science and product teams to turn bold ideas into...PrincipalCasual workWork at officeImmediate startFlexible hours
- Icehouseventures is seeking an Infrastructure Engineer in San Francisco, CA, to build and maintain the foundational Kubernetes platform across... ...security controls, and collaborate closely with SRE and ML teams. Ideal candidates will thrive in a startup environment and...
- The Role: Why, What and the Who Infrastructure Engineers build the foundation for Ivo’s entire platform. Customers are cagey about their contracts... ...(dev → staging → prod). Design strategies to isolate ML vs API workloads while optimizing for cost, performance, and reliability...
$96.8k - $306.4k
...Job Description The Senior Principal AI Agent / ML Software Engineer is a Senior Staff-level, hands‑on technical leadership role responsible for defining, building, and operating next-generation AI systems on Oracle Cloud Infrastructure (OCI). This person will set architecture...PrincipalTemporary workFlexible hours- ...over outcomes. The scope is intentionally open-ended, and strong engineers have enormous leverage here. What You'll Do Set technical... ...8+ years of software engineering experience with significant AI/ML depth and a track record of technical leadership Demonstrated experience...Principal
$300k - $400k
About the Role Principal AI/ML Engineer - AdTech Drive the development of advanced machine‑learning models and AI‑driven features for Zeta’s advertising platform. Design, build, and deploy scalable, low‑latency ML solutions for campaign optimization, user personalization...Principal- ...toward a sustainable future. About the role: As a Senior MLOps Engineer within the Perception Deep Learning team, you will lead the design... ...machine learning models and drive best practices across the ML lifecycle. You will play a key role in shaping the architecture...
- ...most complex and bleeding‑edge part of our engine. You'll be working on making AI models run... ...works You think the current state of ML deployment could be way better What you'll... ...hierarchy, only categories: dev, arts, prod, ops, etc (and no, there is no one here with...
- ...seeking a Senior Manager, Machine Learning Engineering in the Applied Science organization. Lead... ...-class team to design, build, and deploy ML/AI services spanning generative AI,... ...You’ll drive end-to-end ML lifecycle, ML Ops, and responsible AI, with a strong emphasis...
- Senior ML Systems Engineer, Frameworks & Tooling at Cohere Our mission is to scale intelligence to serve humanity. We’re training and deploying... ..., distributed training libraries, or custom kernels/fused ops. Experience with multi-node cluster orchestration (Slurm, Ray...Full timeWork at officeRemote workFlexible hours
- ...learning systems that can reason over biological data and help design better biomolecules. We are seeking an ML Scientist Co‑Op to contribute to protein engineering research, including problems related to generative protein design, antibody engineering, developability,...
$190k - $260k
Role Description As a Senior ML Infrastructure Engineer, you will work directly in the Automation org with the core ML, Ops, and Analytics teams to help improve and build out the infrastructure around model deployment and monitoring. This role is essential to helping scale...$200k - $240k
...safer, more secure world for all. The AI Engineering Team is chartered with enabling next-generation... ...than the market. As a Senior or Staff ML Systems Engineer - LLM , you’ll be at the... ...) Understand and implement ML Ops best practices , including: Model versioning...Remote workWorldwide$170k - $200k
...for training robotics foundation models. The Instawork Robotics ML Engineer will help build and scale the technology powering physical AI... ...Functional Collaboration - work closely with robotics leadership, data ops, QA, and other engineering teams to ensure alignment from...Hourly payInternshipLocal areaFlexible hours$200k - $280k
...voice AI startup is seeking a Founding Senior Machine Learning Engineer to fine-tune and deploy human-like voice agents, handling millions... .... Candidates should have real-world experience in deploying ML models and work well in a fast-paced environment. #J-18808-Ljbffr...- An innovative company is seeking a Distributed Systems/ML Engineer to enhance the training throughput of its internal framework. This role involves collaborating with researchers to develop efficient video models and applying cutting-edge techniques to optimize training...
$145.4k - $261.15k
...needs and price sensitivities. Lead with Influence: Act as a change agent across a matrixed organization, aligning GTM, Product, Pricing Ops, Growth, Analytics, Finance, and more. Communicate Effectively: Regularly engage with VP‑level and executive leadership to deliver...PrincipalLocal area- An AI-focused technology company in San Francisco is seeking a Senior Machine Learning Engineer to take ownership of the full ML lifecycle. You will design, build, and operate ML systems that directly impact the product, emphasizing reliability and cost-efficiency. Aimed...
$164k - $312k
A leading technology company in San Francisco seeks a Senior ML Engineer to drive advanced prediction models for ad ranking systems. You will design and implement efficient systems that optimize engagement predictions. The ideal candidate holds an advanced degree and has...$138k - $289k
Indeed is seeking an experienced Machine Learning Engineer located in San Francisco, California. The role involves delivering impactful ML and AI projects, developing and implementing machine learning solutions, and mentoring team members. This position offers a competitive...- DoorDash is looking for a Senior Staff Machine Learning Engineer to set the personalization strategy for the consumer shopping journey. In this role, you will implement machine learning solutions that enhance the consumer search experience across various services. Your...
- A technology company in San Francisco is seeking an experienced Infrastructure Engineer to ensure 99.99% uptime while working with custom inference stacks and managing GPU loads. The ideal candidate will have deep infrastructure expertise and a passion for tackling complex...
$155.58k - $320.32k
Pinterest is seeking a talented engineer skilled in Python to write production code that powers real-time bidding and model training. Ideal... ...responsibility, including the training and deployment of ML models that drive ad decisions. Located in San Francisco, California...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal ML Ops Engineer. Be the first to apply!
- principal cloud engineer San Francisco, CA
- senior principal engineer San Francisco, CA
- assistant chief engineer San Francisco, CA
- principal infrastructure engineer San Francisco, CA
- general engineer San Francisco, CA
- principal safety engineer San Francisco, CA
- principal application developer San Francisco, CA
- principal engineer San Francisco, CA
- director of product engineering San Francisco, CA
- director data engineering San Francisco, CA

