Scientist R&D - Immunohistochemistry (IHC) & Histology
Natera
Natera seeks a scientist to develop and optimize immunohistochemistry and histology workflows for oncology product development. The role involves assay design, validation studies, and cross-functional collaboration to translate research methods into clinical laboratory processes.
Responsibilities
- Design and execute development, optimization, verification, and validation studies for IHC and tissue workflows
- Develop IHC assays including antibody selection, antigen retrieval, staining conditions, and performance assessment
- Evaluate and optimize histology and pre-analytical variables including tissue processing and slide preparation
- Troubleshoot automated staining platforms and investigate artifacts, reagent performance, and assay variability
- Author protocols, validation reports, SOPs, and provide technical guidance during method transfer to clinical operations
Requirements
- Ph.D. in Pathology, Cancer Biology, Molecular Biology, or related field with 2+ years industry experience
- Master's degree with 5+ years relevant industry experience, or Bachelor's with 6-8+ years
- Hands-on expertise in IHC assay development, optimization, and troubleshooting
- Solid knowledge of histology and FFPE tissue workflows
- Experience with antibody characterization, antigen retrieval, and staining optimization
- Experience with automated IHC/ISH platforms, particularly Roche BenchMark ULTRA
- Proficiency with data analysis tools such as Excel and JMP
Vacancy posted 7 days ago
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