Director, Enterprise Applications, IT (Commercial)

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Job Summary About IDEAYA Biosciences: IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications. Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer. When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward. For more information, please see Location: South San Francisco, CA. Position Summary: IDEAYA Biosciences is seeking a Director, Enterprise Applications, IT (Commercial Systems) to lead the strategy, delivery, and operations of the Commercial IT applications and data ecosystem. This role is responsible for enabling scalable, compliant, and insight-driven technology solutions supporting Commercial Operations, Sales, Marketing, Market Access, and Medical Affairs across the full commercialization lifecycle. The Director will serve as the primary IT Business partner to Commercial leadership, translating business strategy into enterprise technology roadmaps and delivering integrated systems including CRM, Commercial Data Warehouse, Master Data Management, and advanced analytics platforms. This role will ensure systems are designed for launch readiness, operational excellence, and long-term scalability to support IDEAYA’s transition and growth as a commercial-stage biotechnology company. This position is based in our South San Francisco headquarters and requires onsite presence four days per week per company policy. Reporting to: Sr. Director, Enterprise Applications and IT Compliance Job Description What you’ll do: Lead the end-to-end strategy, design, implementation, and operations of the Commercial IT application and data ecosystem, including CRM, Commercial Data Warehouse, Master Data Management, and analytics platforms. Translate Commercial and Medical Affairs business priorities into scalable, compliant, and actionable technology solutions aligned to commercialization strategy. Partner closely to define technology roadmaps aligned with business objectives, governance, KPIs, and success metrics. Own the delivery of integrated commercial systems supporting Sales, Marketing, Market Access, and Medical Affairs, ensuring launch readiness and post-launch scalability. Serve as the key interface between Commercial applications and enterprise data/analytics platforms to ensure consistent, trusted, and actionable insights. Drive end-to-end execution of system implementations, integrations, and enhancements across CRM, data warehouse, MDM, and reporting environments. Oversee vendor and service provider ecosystems, managing delivery performance, accountability, and financial outcomes across all Commercial IT initiatives. Develop and manage IT budgets, forecasts, and investment cases for Commercial IT initiatives. Provide executive-level communication on program status, risks, dependencies, and decisions. Build and lead high-performing teams, including internal staff and external partners/MSP’s. Continuously assess industry trends and emerging technologies across AI, data platforms, and digital commercial ecosystems to drive innovation and improve Commercial IT capabilities. Embed governance, compliance, and regulatory requirements (SOX, HIPAA, CFR 21 Part 11, Sunshine Act) into all system design and operations. Requirements: Bachelor’s degree in information systems, Computer Science, Engineering, or related field; advanced degree preferred. 12-15 years of progressive IT experience, including 10+ years in leadership roles. Strong experience in Commercial IT environments, preferably in pre-launch, launch, and post-launch phases. Proven expertise in CRM (e.g., Salesforce/Veeva), Commercial Data Warehouse, MDM, reporting, and analytics platforms. Deep understanding of Commercial pharmaceutical processes across Sales, Marketing, Market Access, and Medical Affairs. Management experience in Commercial IT and Data Warehouse/Reporting. Experience with integrated platforms leveraging Veeva CRM, Informatica, Snowflake, Databricks, along with advanced analytics and AI/ML capabilities. Strong knowledge of regulated environments including SOX, HIPAA, CFR 21 Part 11, and related compliance frameworks. Demonstrated success leading high performance IT teams, managing vendors, and delivering enterprise-scale programs. Strong understanding of cloud architecture, integration frameworks, and data platforms. Hands-on leadership style with strong analytical thinking, judgment, and execution capability. All employees are expected to act with integrity and in full compliance with applicable laws, regulations, and IDEAYA policies, including IDEAYA’s Code of Conduct. Employees must demonstrate good judgement and ethical behavior in all business activities, maintain patient and product safety as a top priority, and report any suspected violations of law or Company policy through appropriate channels Total Rewards Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs. The expected salary range for the role of Director, Enterprise Applications, IT (Commercial) is $209,000 - $258,000. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates’ experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process. The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite in the office at the Company’s facilities for training & meetings, with work-from-home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization. IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets. We are committed to providing reasonable accommodations to qualified individuals with disabilities. If you need assistance or an accommodation due to a disability, please get in touch with us at View email address on click.appcast.io. At IDEAYA we believe in the importance of on-site presence by all team members as an essential ingredient to effective collaboration. Our hybrid approach to work at IDEAYA includes all staff being on-site four days per week in the office, and one day per week working from home. IDEAYA Company Values: Passionate Commitment Fearless Innovation Courageous Integrity Respectful Teamwork Objective Decision-Making Empowered Accountability For more information, please see California Job Applicant Privacy Notice