Senior Supply Chain Manager

DescriptionArdelyx is a commercial-stage biopharmaceutical company focused on redefining treatment approaches for patients with significant unmet medical needs. By combining scientific innovation with a collaborative, purpose-driven culture, we strive to create meaningful impact for patients. Team Ardelyx is united by a shared mission and guided by our core values: Passionate, Fearless, Dedicated, and Inclusive. We foster an inclusive environment where employees are respected, supported, and empowered to make an impact — both within our company and in the lives of patients we serve.This is a hybrid role (2-3 days in office) at our Waltham, MA headquarters. Position Summary:This role is responsible for leading and supporting Ardelyx's API external manufacturing, inventory management, and contract manufacturing organization (CMO) partners. The Senior Supply Chain Manager provides oversight of CMO partners to ensure the timely delivery of materials, effective cost management, supply continuity, and execution of change controls.Working closely with Supply Chain team, Technical Operations, Quality, CMOs, and other cross-functional partners, this role supports API production activities across the supply network. Key responsibilities include monitoring inventory accuracy, resolving supply chain issues, coordinating logistics activities, ensuring compliance with ex-US market requirements, and driving continuous improvement initiatives across the API supply network.The ideal candidate brings strong pharmaceutical supply chain experience, exceptional organizational and project management skills, and the ability to manage multiple priorities in a fast-paced, cross-functional environment. Responsibilities:Partner with third-party manufacturers to align production schedules, raw materials, quality requirements, and regulatory compliance for small molecule APIs Manage Ardelyx inventory across API-related CMO sites, ensuring accurate inventory control and efficient supply chain operationsManage purchase requisitions and purchase orders related to small-molecule API manufacturing and material movements. Monitor expenses against approved budgets and support accrual processes with Finance and AccountingWork cross-functionally with Quality Assurance, CMC, and Regulatory Affairs to support supply planning activities, identify potential risks, and develop proactive mitigation plansUse ERP systems and planning tools to model scenarios, track supply risks, and optimize logistics. Maintain supply chain policies, procedures, and documentation and support training activities as neededPrepare reports, metrics, and presentations for management and cross-functional stakeholdersComplete API and RSM related change control impact assessmentsWork with Supply Chain Director to ensure ex-US alliance orders are delivered timely and in accordance with contractual obligations and requirementsQualifications:BA/BS in a technical, scientific, engineering, supply chain, or related discipline with 6 -8 years of experience in pharmaceutical supply chain or CMC project management.Demonstrated experience in API project management or supply chain for a virtual supply chain networkExperienced in managing external manufacturing relationshipsStrong interpersonal skills and the ability to collaborate effectively with cross-functional teams and external partnersDetail oriented with strong analytical and computer skillsExcellent negotiating and problem-solving abilitiesStrong oral and written communication skillsDemonstrated ability to organize and prioritize multiple tasks, manage competing, and meet deadlines in a fast-paced environmentUp to 15% travel requiredThe anticipated annualized base pay range for this full-time position is $135,000 - $165,000. Ardelyx utilizes industry data to ensure that our compensation is competitive and aligned with our industry peers. Actual base pay will be determined based on a variety of factors, including years of relevant experience, training, qualifications, and internal equity. The compensation package may also include an annual bonus target and equity awards, subject to eligibility and other requirements. Ardelyx also offers a robust benefits package to employees, including a 401(k) plan with generous employer match, 12 weeks of paid parental leave, up to 12 weeks of living organ and bone marrow leave, equity incentive plans, health plans (medical, prescription drug, dental, and vision), life insurance and disability, flexible time off, annual Winter Holiday shut down, and at least 11 paid holidays. Ardelyx is an equal opportunity employer.We do not accept unsolicited resumes from search firms, or recruiters or similar vendors. Any such unsolicited resume submitted to any employee or through Company's career site without a valid, signed search agreement signed by Company's authorized representative will be deemed the property of the company, and no fees will be paid in the event of a hire. Company will have the right to hire any such candidate at its discretion without any financial obligation or fee owed to the vendor. Any verbal or written communication with a Company employee outside of this process will not be considered a binding agreement.