Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Principal Scientist, Outcomes Research

$210.4k - $331.1k
Full-time

Merck Sharp & Dohme Corp

In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company’s renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health.

The Senior Principal Scientist leads a team of health economists to develop and implement health economics and modeling strategies that enable the Company to understand and communicate the full economic value of the Company’s oncology products to payers, health technology agencies, policy makers, and other decision-makers in order to optimize market access and patient outcomes.

Main Responsibilities:

Under the direction of an Executive Director within the Health Economic and Decision Sciences (HEDS) department of the BARDS) organization, the Senior Principal Scientist will:

  • Lead a team in the development and execution of health economic and modeling strategies to support the value of the Company’s oncology portfolio

  • Provide leadership, mentorship, and strategic direction to a team of 3–4 health economists

  • Oversee the prioritization and development of high-quality global health economic models and tools to support market access, pricing, reimbursement, HTA submissions, and formulary decision-making across U.S. and international markets

  • Collaborate with key countries and the regional team to adapt global models for local HTA, reimbursement, and formulary submissions

  • Generate and communicate early health economic insights to inform development and commercialization strategies

  • Build strong partnerships with internal stakeholders to ensure modeling strategies align and support the overall product development and value evidence strategy and implementation

  • Develop and maintain relationships with external thought leaders in health economics, decision sciences, and health policy to enhance scientific credibility, inform strategy, and position our company as a leader in the field

Qualifications:

Education

  • PhD (preferred) in Quantitative Sciences such as Health Economics, Mathematics, Predictive Modeling, Statistics, Operations Research, Physics, Engineering or closely related field with 7 or more years of relevant experience; or

  • Master’s degree with at least 9 years of relevant work experience

Required Experience and Skills

  • Demonstrated ability to lead and manage teams

  • Excellent written and verbal communication skills

  • Strong strategic thinking and problem-solving skills

  • Ability to work independently and interact effectively with a broad group of stakeholders

  • Ability to manage multiple priorities and deadlines

  • Ability to translate complex analyses into actionable insights

  • Experience in developing health economic models for decision-making

  • Strong expertise in oncology modeling

  • Experience with HTA and reimbursement submissions

BARDS2020

#eligibleforERP

Required Skills:

Commercialization, Data Management, Decision Models, Healthcare Technology, Health Economics, Market Access, Mathematics, Medical Economics, Mentorship, Prioritization, Product Development, Researching, Stakeholder Relationship Management, Strategic Planning, Strategic Planning Partnerships, Strategic Thinking

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

The salary range for this role is

$210,400.00 - $331,100.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at .

You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Vacancy posted 9 hours ago
Similar jobs that could be interesting for youBased on the Senior Principal Scientist, Outcomes Research in West Point, PA vacancy
  • $190.8k - $300.3k

     ...resides within the company's Value and Implementation (V&I), Outcomes Research organization, responsible for real‑world evidence generation...  ...and improve patient health outcomes. Under the guidance of a senior leader, this individual will support the V&I, Outcomes Research... 
    Principal
    For contractors
    Local area
    Worldwide

    Merck & Co. Inc

    North Wales, PA
    2 hours ago
  • $286.9k

     ...Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology Translational Medicine in our Research & Development Division is responsible for planning and managing an important inflection point in the drug development process, working closely... 
    Principal
    Senior
    Worldwide

    Merck

    West Point, PA
    1 day ago
  • $282.2k

     ...Senior Clinical Director (Senior Principal Scientist) The Senior Clinical Director (Senior Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed medicines in the Late Stage Oncology - Late Stage... 
    Principal
    Senior
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck

    North Wales, PA
    5 days ago
  • $282.2k

     ...JOB DESCRIPTION Job Description The Senior Clinical Director (Senior Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new medicines in the Oncology Asset therapeutic area. Our company's Oncology Asset... 
    Principal
    Senior
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck

    North Wales, PA
    2 days ago
  • $156.9k - $247k

    Job Description Title: Associate Principal Scientist/Associate Director, Outcomes Research Division / Area: Value and Implementation Workday Job Profile: Consult...  ...Resources Role Summary Under the guidance of a senior leader, an Associate Principal Scientist/Associate... 
    Principal
    Full time
    For contractors
    Local area
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    MSD

    North Wales, PA
    4 days ago
  • $137k - $235.75k

     ...patients every step of the way. We are searching for a Senior Principal Scientist, Computational Multiomics, Precision Measures , to be in...  ...Affairs, Data Science & Digital Health, Patient Reported Outcomes, Statistics to contribute to holistic measurement plans (across... 
    Principal
    Senior
    Full time
    Temporary work
    Work at office
    Local area
    Remote work
    2 days per week

    Johnson & Johnson

    Spring House, PA
    4 days ago
  •  ...Job Description We are a research‑driven biopharmaceutical company. Our mission is built on the...  ...innovative medicines and vaccines that improve outcomes globally. We have an exciting opportunity for an Associate Principal Scientist, Health Economics to join our team in... 
    Principal
    Local area

    Merck & Co. Inc

    Lansdale, PA
    3 hours ago
  • $142.4k - $224.1k

     ...Merck & Co. is seeking an Associate Principal Scientist, Drug/Device Combo Products in West Point, PA. You will lead design controls for medical devices, engaging with cross-functional teams to ensure compliance and successful product launches. The ideal candidate will... 
    Principal
    Senior

    Merck & Co. Inc

    Lansdale, PA
    2 hours ago
  •  ...Johnson & Johnson is seeking a Principal Scientist, Nonclinical Safety Lead in Spring House, PA. This hybrid role entails leading the nonclinical safety team, providing toxicology leadership across various therapeutic projects, and ensuring effective collaboration with... 
    Principal
    Senior

    Johnson & Johnson

    Spring House, PA
    2 hours ago
  • $173.2k - $272.6k

     ...Job Overview In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the-art scientific... 
    Principal
    For contractors
    Local area
    Flexible hours

    MSD Malaysia

    North Wales, PA
    1 day ago
  •  ...Principal Scientist, Nonclinical Safety Lead Job Function: Discovery & Pre-Clinical/Clinical Development...  ...interface between the project team and senior management. Lead the team of...  ...InvestigationsSafety-Oriented Scientific Research Johnson & Johnson is an Equal Opportunity... 
    Principal
    Local area

    Johnson & Johnson

    Spring House, PA
    5 days ago
  •  ...Overview The Associate Principal Scientist position will support our Live Virus Vaccines (LVV) franchise. This broad role includes working...  ..., effective collaboration with external contract providers, research laboratories, supply chain, site and global Quality, and CMC... 
    Principal
    Contract work
    Temporary work
    For contractors

    Merck & Co. Inc

    Lansdale, PA
    2 hours ago
  • $117k - $184.2k

    Merck & Co. is seeking a Senior Research Scientist in West Point, Pennsylvania, to lead efforts in biotransformation and metabolite identification. The role involves designing experiments to elucidate drug metabolites and collaborating with cross-functional teams to support... 
    Senior

    Merck & Co.

    West Point, PA
    3 days ago
  • $142.4k - $224.1k

     ...Job Description Associate Principal Scientist, Statistical Programming: Provide high quality statistical programming analysis and reporting...  ...field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at... 
    Principal
    For contractors
    Work at office
    Local area
    Remote work
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work
    3 days per week

    Dormont Manufacturing Company

    North Wales, PA
    3 hours ago
  • $260.3k - $409.7k

     ...Principal Scientist Translational Medicine Translational Medicine is responsible for early clinical development of novel therapeutics, working...  ...Discovery Sciences and late-stage Immunology Clinical Research. We work with all therapeutic areas within our Research Division... 
    Principal
    Worldwide

    Merck

    North Wales, PA
    3 days ago
  • $142.4k - $224.1k

     ...execution of clinical protocol(s). Serves as the lead clinical scientist on the clinical trial team. Collaborates with the Medical...  ...activities on clinical protocols. Apply strong knowledge of clinical research regulatory requirements (e.g., GCP and ICH). Manage multiple... 
    Principal
    Flexible hours
    Shift work

    Merck & Co.

    North Wales, PA
    4 days ago
  •  ...Pre-Clinical/Clinical Development Job Sub Function Biological Research Job Category Scientific/Technology All Job Posting...  .... Learn more at We are searching for the best talent for a Senior Scientist, Mass Spectrometry, to be located in Spring House, PA. Purpose... 
    Senior
    Local area

    Johnson & Johnson

    Spring House, PA
    4 days ago
  • $109k - $174.8k

    Job Title Senior Scientist, AI Applications, R&D Oncology Locations Spring House, PA (preferred) Cambridge, MA San Diego, CA (La Jolla area...  ...familiarity with biological data types, especially in oncology research. Strong grasp of statistics and methods to validate model... 
    Senior
    Local area

    6084-Janssen Research & Development, LLC Legal Entity

    Spring House, PA
    4 days ago
  • Senior Research Scientist (R3) - Biotransformation & Metabolite Identification Location: West Point, Pennsylvania (On-site). Position Overview The DMPK group at our company's Research Laboratories is seeking a highly skilled and driven Senior Research Scientist (R3) with... 
    Senior
    Relocation
    Visa sponsorship
    Flexible hours

    Merck & Co.

    West Point, PA
    4 days ago
  • $117k - $184.2k

    Job Description: Process Development Scientist At our company, we aspire to be the premier research-intensive biopharmaceutical company. We are at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in... 
    Senior
    Contract work
    For contractors

    MSD Malaysia

    West Point, PA
    4 days ago
  • $117k - $184.2k

    Job Overview We are seeking a Senior Scientist to join our Digital Insights team within the Development Sciences and Clinical Supply (DSCS)...  ...networks. Have a demonstrated ability to publish and present research, including an established track record of interaction with... 
    Senior
    For contractors
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    West Point, PA
    4 days ago
  •  .... This role focuses on accelerating transformational medicine development through computational strategies and collaboration with research teams. Applicants should possess a PhD in Computational Chemistry and experience in drug design, AI/ML, and coding in Python. The... 
    Principal
    Remote work

    GlaxoSmithKline

    Collegeville, PA
    1 day ago
  • $204k - $340k

     ...successful, there must be robust health outcomes data to support launch optimization,...  ...Real‑World Evidence & Health Outcomes Research Scientist is critical to achieving this ambition...  ...The role will report directly into the Senior Director, Global Real‑World Evidence &... 
    Local area

    GSK LLP

    Collegeville, PA
    2 hours ago
  • $142.4k - $224.1k

     ...to make a difference through innovative research, discovery, and development of life-...  ...exciting opportunity for an Associate Principal Scientist with significant experience in antiviral...  ...range of stakeholders, including peers, senior leaders, partner organizations and external... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    MSD

    Upper Gwynedd, PA
    4 days ago
  •  ...Job Summary GSK has an immediate opening for an NMR spectroscopist in research and development at our site in Collegeville, PA. The position is part of the NMR team accountable for all NMR applications in support of drug discovery and development from lead identification... 
    Principal
    Local area
    Immediate start

    GlaxoSmithKline

    Collegeville, PA
    2 hours ago
  •  ...GSK’s therapeutic requirements for clinically differentiable medicines. The successful applicant will collaborate with preclinical research and development business partners to impact the pipeline from target identification, modality selection, and molecule design to... 
    Principal
    Internship
    Local area
    2 days per week
    3 days per week

    GlaxoSmithKline

    Collegeville, PA
    1 day ago
  • $117k - $184.2k

    Job Description Senior Scientist, Hybrid Modeler, Digital Insights, DSCS Digital Technologies We are a global biopharmaceutical leader with...  ...humanity and continue to be one of the world’s biggest investors in Research & Development. We are seeking a Senior Scientist to join our... 
    Senior
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    MSD

    Upper Gwynedd, PA
    3 days ago
  •  ...Development Chemist III in Conshohocken, PA. This role involves developing and formulating metalworking fluids, conducting product research, and mentoring junior chemists. Candidates must have a Bachelor’s degree in Chemistry with significant experience or higher... 
    Senior

    Tribonet

    Conshohocken, PA
    2 hours ago
  •  ...An innovative firm is seeking an Associate Principal Scientist specializing in Clinical Outcome Assessment. This pivotal role involves coordinating global strategies for Patient-Reported Outcomes and ensuring alignment with regulatory requirements. You will collaborate... 
    Senior

    The Fountain Group

    Lansdale, PA
    4 days ago
  • Principal Data Scientist - Ontology Developer (TDS) Position Summary Design, build, and govern semantic frameworks that unify data across the development...  ...multiple projects simultaneously and deliver high‑quality outcomes. Preferred Experience with biopharmaceutical development,... 
    Principal
    Immediate start

    Scorpion Therapeutics

    Spring House, PA
    4 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Principal Scientist, Outcomes Research. Be the first to apply!