Senior Quantitative LC-MS Scientist, Protein Bioanalysis
Amgen SA
Amgen is seeking a highly skilled scientist for the Pharmacokinetics & Drug Metabolism – Bioanalytical Sciences group to advance LC-MS based assays. You will develop and apply fit‑for‑purpose methods to quantify target proteins, evaluate target engagement and biomarker kinetics, and support discovery through regulatory submissions. You will work closely with cross‑functional teams to translate analytical results into mechanistic understanding of drug biology, contributing to Amgen’s mission to #J-18808-Ljbffr Amgen SA
$143.82k - $194.58k
...Amgen seeks a Senior Scientist to develop and optimize quantitative LC-MS bioanalytical assays for protein characterization and target engagement studies. The role supports drug... ...s degree with 4+ years of relevant LC-MS bioanalysis experience, or Bachelor's with 6+ years...Senior- ...innovative, fit‑for‑purpose LC-MS‑based bioanalytical... ...of endogenous proteins, including distinct proteoforms... ...programs. This scientist will be expected to identify... ...fit‑for‑purpose quantitative LC-MS assays to measure... ...development and quantitative bioanalysis in complex biological...Senior
- Amgen seeks a scientist in Pharmacokinetics & Drug Metabolism - Bioanalytical... ...(PKDM-BA) to develop and apply LC-MS-based bioanalytical assays for endogenous proteins, proteoforms, and target-drug... ...development and a strong quantitative mindset. The successful candidate...Senior
$167.4k - $310.8k
...Intelligence (AI) to assist our scientists in both pRED and gRED... ...a highly motivated Senior Machine Learning... ...machine learning models for protein and antibodies in zero... ....Who you areBS, MS, or PhD degree in the... ...Chemical Engineering) or quantitative field (e.g. Computer...SeniorFull timeLocal areaWorldwideRelocation packageShift work$140k - $210k
...Senior Scientist/Principal Scientist, Protein Sciences: Analytical & Biophysical Characterizations Department: Technology/Protein Sciences Work Location... ...analytical and biophysical methods (with emphasis on LC-MS, chromatography, thermal/structural assays, and...SeniorFull timeTemporary workFlexible hours- Amgen is seeking an Associate Scientist in Discovery Proteomics in South San Francisco to expand LC-MS/MS‑based proteomics capabilities. You will execute quantitative workflows, prepare samples from diverse biological matrices, and collaborate with biology, bioinformatics...
- Nurix Therapeutics seeks a Scientist to lead bioanalytical strategies for next-generation... ...conjugates (DACs). The role emphasizes LC-MS/MS and hybrid assays to analyze bioconjugates... ...interface of small and large molecule bioanalysis, contribute to assay development and...
- Amgen is seeking an Associate Scientist Discovery Proteomics in South San Francisco to expand expertise in LC-MS/MS-based proteomics and support early discovery programs. You will execute workflows for quantitative proteomics, including cell-surface target discovery, proximity...
$169.32k - $219.12k
...create possible, together. Job Description The Senior Scientist, Protein Therapeutics will help strengthen our Antibody Drug Conjugate... ...advanced analytical methods, including high-resolution LC-MS (intact and subunit mass analysis), peptide mapping, multidimensional...SeniorFull timeFor contractorsLocal area- IDEAYA is seeking a Senior Principal Research Scientist to lead the Protein Sciences group at our South San Francisco headquarters. The role focuses on solving protein production challenges, mentoring scientists, and coordinating CROs for expression and characterization...Senior
- ...South San Francisco, CA, seeks a Principal Scientist to lead formulation and drug product development for a growing portfolio of protein biologics. You will design studies,... ...therapeutics, strong analytical skills, and hands-on LC-MS, HPLC, and cIEF experience. Collaboration...
- ...assays and familiarity with quantitative bioanalysis to support development of... ...and induction assays, protein binding assays Track record... ...expertise in bioanalysis using LC-MS/MS Primary... ...candidate will work closely with senior scientists within the group to support...Immediate start
- ...assays and familiarity with quantitative bioanalysis to support development of... ...and induction assays, protein binding assays • Track record... ...expertise in bioanalysis using LC-MS/MS Primary... ...candidate will work closely with senior scientists within the group to support...
- ...Role We are seeking a Senior or Principal Analytical Scientist with deep, hands‑on... ...to own our MS function end-to-end... ...for high-throughput protein profiling in neurons... ...with nano-/micro-flow LC and robotic sample introduction... ...Establish robust quantitative proteomics workflows...SeniorContract workShift work
- ...Senior Scientist role focused on developing and deploying automated computational pipelines for large-scale protein binder design. The position supports molecular discovery efforts by accelerating generation of design candidates and libraries across multiple therapeutic...Senior
$161.9k - $173.9k
...Senior Scientist - Degrader Antibody Conjugate Cellular Nurix Therapeutics... ...of targeted protein degradation medicines the next... ...screening through mechanistic and quantitative characterization. ~ Serve... ...oracademicresearch experience or MS with8or moreyears...SeniorFull time- Twist Bioscience seeks an exceptional R&D scientist in South San Francisco to lead protein sciences with antibody focus. You will be hands-on while shaping the technical roadmap, and later manage a team as the group grows. Expect to balance bench work with strategic design...Senior
$175k - $190k
Principal Scientist / Associate Director, Developability & Protein Sciences About Cartography Biosciences Cartography Biosciences is advancing a differentiated... ...degradation studies, PTM mapping (e.g. peptide mapping LC-MS), and early formulation development. Help define...$146.4k - $198.08k
...thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Scientist - Computational Protein Design What you will do Let's do this. Let's change the world. In this vital role you will develop and deploy...SeniorFull timeFlexible hours$167.4k - $310.8k
...Intelligence (AI) to assist our scientists in both pRED and gRED to... ...techniques. We are seeking a Senior or Principal Machine... ...Mathematics, Physics, or a related quantitative field.Experience: For Senior... ...molecular modalities (e.g., protein sequences, chemical graphs,...SeniorFull timeLocal areaWorldwideRelocation package$123.8k - $143.1k
...Scientist I Bioanalytical Drug Antibody Conjugates (DACs... ...commercialization of targeted protein degradation medicines... ...role will focus on LC-MS/MS and hybrid assay strategies for quantitative and qualitative... ...small and large molecule bioanalysis and will contribute to...Full timeContract work- ...commercialization of targeted protein degradation medicines,... ...is seeking a Scientist to lead bioanalytical strategies... ...role will focus on LC-MS/MS and hybrid assay strategies for quantitative and qualitative... ...small and large molecule bioanalysis, and will contribute to...
- Amgen in South San Francisco, CA, is seeking a Senior Scientist - PKDM-BA to design and execute biological and biophysical experiments to understand ADME properties of large molecule therapeutics in support of drug discovery and early development. This lab-based role emphasizes...Senior
- ...Senior Scientist position at Amgen focused on designing and executing biological and biophysical... ...5+ years related experience ~ PhD or MS in immunology, cell biology, biochemistry... ...biophysics, or equivalent field ~2+ years protein therapeutics drug discovery and...Senior
$159k - $207k
...and motivated Principal Scientist to provide strategic... ...development experience for protein therapeutics in the... ...biopharma industry; or BS/MS with a minimum of 14... ...capillary electrophoresis, LC/MS, peptide mapping,... ...tandem mass spectrometry, quantitative analysis, and host cell...Contract workLocal area$268k - $358k
...Life Sciences AI, the AI for Protein Engineering team develops... ...leads. We are looking for a senior individual contributor... ...collaborate with experimental scientists, AI researchers, and platform... ...Bioengineering, or a related quantitative field. • Strong track record...SeniorFull timeWork at officeLocal areaFlexible hours- ...patients while transforming your career. Senior Scientist - PKDM-BA What you will do Let's do this... ...Preferred Qualifications: PhD or MS in immunology, cell biology, biochemistry... ...biophysics, or equivalent. 2+ years of protein therapeutics drug discovery and development...SeniorFlexible hours
$101.4k - $154.7k
POSITION SUMMARY:The Senior Field Application Scientist, Protein XI (FAS) will play a critical role in supporting the launch and ongoing success of a new, cutting-edge proteomic technology platform. This individual will serve as a scientific expert for customers and internal...SeniorFull timeTemporary workFlexible hours- ...is looking for a hands-on, bench-driven scientist to perform IND-enabling developability assessments... ...materials. Develop highly sensitive protein characterization methods (qSEC, RP-HPLC,... ...: SEC, HIC, CE-SDS, DLS, DSF, ELISA, LC-MS. Track record of translating complex...SeniorFull timeContract work
- ...process development expertise in purification, process characterization, validation, and analytical methods (HPLC, ELISA, SDS-PAGE, DLS, LC/MS) familiarity with BLA authoring and working with CMOs experience with viral clearance studies and AKTA systems is preferred High-...Senior
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