Director, Commercial Insights and Analytics

Director, Commercial Insights and Analytics Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Team Olema , with our transfor mation into a fully integrated oncology company well underway , t op-line data from our lead program expected later this year , and our first potential commercial launch on the horizon. Our leadproduct candidate,palazestrant, isa novel, orallyavailablecomplete estrogen receptor antagonist (CERAN)and selective estrogen receptor degrader (SERD)currently intwopivotalPhase 3clinicaltrials.We expect top-line data from OPERA-01,ourongoingPhase 3 trial ofpalazestrantas a monotherapy in patients withsecond- or third-lineER+/HER2-metastatic breast cancer (MBC), in the fallwhich, if successful, could lead to our first potentialapproval andcommercial launchin 2027. OPERA-02,ourPhase 3 trial ofpalazestrantin combination withribociblibin patients with frontlineER+/HER2- MBC, isenrolling patients.Togetherwith itsmechanism of action, pharmacokinetic properties,andthe potential todemonstrateactivity in bothESR1wild-type and mutant tumors,palazestranthas the potential totransform the metastatic breast cancer treatment paradigm andaccessa$15 billionglobal market opportunity. Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor withthepotential to generate further value and meaningfullyimpactthemetastatic breastcancertreatment landscape – particularly in combination withpalazestrant.We recently reportedencouragingPhase 1monotherapydata from this programacross multiple solid tumor types andareadvancingpatientenrollment in theongoingcombinationarmsin MBC. Aspiring to transform the metastatic treatment paradigmis an ambitious endeavor that requires aresolute approach todeveloping better therapies and apassionateteamdedicated tohelping the patients we serve feelbetter,longer.Wepossessadeepcommitment toour shared purpose,thesustained pursuit of excellence, cultivatingthecouragerequiredto advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day. Ifyou’rereadyto bepartof atenacious,courageous,agile, andgrowingteam,join us in makinga profound impact,together– for our patients, for your career, and for what’s beyond . About the Role>>>Director, Insights and Analytics Olema Oncology is seeking a Director, Commercial Insights and Analytics to build and lead an integrated insights capability supporting commercial strategy, launch readiness, and lifecycle planning. The role reports to the SVP, CommercialStrategyand Operations. The Director of Insights and Analytics will serve as a strategic thought partner to Commercial leadership and cross-functional stakeholders, bringing together primary market research, forecasting, and competitive intelligence, to address Olema’s most important business questions. This individual will develop a deep understanding of customers, patients, and competitors, and translate that understanding into clear implications and recommendations for the business. The role willbe responsible forensuring that Olema has the right insights at the right time to inform decisions ranging from product strategy and launch planning to customer engagement, market development, and investment prioritization. This is a highly visible, hands-on role for a leader who is comfortable framing ambiguous business questions, designing research and analytical approaches, pressure-testing assumptions, and translating disparate information into executive-ready recommendations. This role will be based out of either our San Francisco or Boston offices and will require approximately 20%travel. Your work will primarily encompass: Integrated Insights & Strategic Decision Support Serve as the lead insights thought partner to Commercial leadership,identifyingthe critical questions, risks, and opportunities that should inform strategy and execution. Lead an integrated insights planning process and synthesize primary research, secondary data, competitive intelligence, epidemiology, and market developments into a cohesive market perspective. Translate insights into clear implications and recommendations,identifyingpriority knowledge gaps and theappropriate approachto address them. Primary Market Research & Customer Insights Own the primary market research strategy and annual research plan supporting Olema’s portfolio and commercialization priorities. Design and execute qualitative and quantitative research to generate insights into unmet needs, treatment decisions, productperceptions, adoption barriers, and market opportunities. Forecasting & Market Assessment Lead the development, refinement, and governance of patient-based commercial forecasts for Olema’s late-stage portfolio,incorporating epidemiology, patient flow, market research, competitive dynamics, access assumptions, analogs, and clinical and regulatory events. Develop and communicate scenario-based forecasts to support long-range planning, portfolio prioritization, lifecycle strategy, and business development assessments. Lead commercial competitive intelligence for Olema’s priority disease areas,maintainingan integrated view of competitors, emerging mechanisms, and evolving treatment paradigms. Lead synthesis around major congresses, data readouts, regulatory events, and other high-impact milestones. Launch Readiness & Performance Insights Define the strategic measurement framework for launch, including KPIs and leading indicators spanning patient dynamics, customer engagement, access, adoption, and market evolution. Partner withanalyticalcolleagues to ensure required data, reporting, and measurement capabilities are in place. Lead interpretation of launch performance, integrating quantitative signals with primary research, field insights, and competitive context toidentifydrivers and recommended actions. A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. Allemployeeswithin our company play aunique andcrucial rolein our success, both inaccomplishingour mission and buildinga positivecompany culture. As such, we are looking forsomeone withthe right combination of knowledge, experience, and attributes for this role. Knowledge: Bachelor’s degreerequired; MBA,PhD, or another relevant advanced degree preferred. Strong understanding ofbiopharmaceutical commercializationin oncology markets, including patient journeys, customer behavior, treatment dynamics, market access, and launch performance. Deepexpertiseinanalytical methodologies sufficient to frame business questions, interpret outputs, challenge assumptions, and partner effectively with technical and analytical colleagues. Experience: 10+yearsof progressive responsibility in biopharmaceutical market research, insights, forecasting, competitive intelligence, commercial strategy, management consulting, or related disciplines . Forward-looking approach to insights generation, including the use of AI-enabled tools, automation, and other modern research methodologies to increase the speed, scale, and quality of market research and strategic insights. Track recordof successfullysupporting late-stage assets, launch planning, and in-market brands. Strong capability in patient-based commercial forecasting, scenario analysis, and market assessment. Proven ability to integrate primary research, competitive intelligence, secondary analyses, epidemiology, and other evidence into a coherent strategic perspective. Effective at presenting recommendations and influencing decisions with senior executives and cross-functional leadership teams. Successful management of agencies, consultants, and other external partners. Attributes: Strategic synthesizer: Connects disparate information andidentifiesthe insights that matter most to a business decision. Structured problem solver: Frames ambiguous questions into clear hypotheses, workstreams, and decision pathways and brings a consulting-style rigor to problem solving. Collaborative: Works effectively across disciplines and develops strong partnerships across Commercial,Analytics,DataScience, Market Access, Medical Affairs, Clinical Development, Finance, and other functions. Comfortable with ambiguity: Thrives in a fast-moving environment where information is incomplete and priorities evolve. High integrity: Brings rigor, objectivity, sound judgment, and appropriatechallengeto strategic decision-making. The base pay range for this position is expected to be $230,000 - $250,000 annually,howeverthe base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.

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We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated. We offer a competitive compensation and benefits package , seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. #J-18808-Ljbffr Olema Oncology